Data as of Oct 27, 2026.
XBI leveraged and inverse ETFs
As of Oct 27, 2026, 3 ETFs aim to return −3x to 3x the daily move in biotech (XBI).
IQ · Oct 27, 2026More about this list
2 issuers sell them. Over three months they finished from −10.1 to −5.9 percentage points against what their stated multiples implied.
All 3 leveraged and inverse ETFs on XBI
| Ticker | Fund | Issuer | 1M vs multiple | 3M vs multiple | 1Y vs multiple | Net assets ↓ | Net assets as of | Fee | Total return 1M | Total return 3M | Total return YTD | Total return 1Y | Total return 3Y | Total return since launch | Multiple |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LABU | Direxion Daily S&P Biotech Bull 3X ETF | Direxion | −3.7 pts | −10.1 pts | −26.7 pts | $586m | Oct 26, 2026 | 0.96% | −4.0% | +0.1% | +52.0% | +91.2% | +396.4% | −92.1% | +3x |
| LABD | Direxion Daily S&P Biotech Bear 3X ETF | Direxion | −4.1 pts | −8.8 pts | not comparable | $66m | Oct 26, 2026 | 1.07% | −3.8% | −19.0% | −65.3% | −74.4% | −97.3% | −100.0% | −3x |
| XBIX | Corgi U.S. Biotech 2x Daily ETF | Corgi | −2.3 pts | −5.9 pts | – | $338,071 | Oct 27, 2026 | 0.45% | −2.5% | +0.9% | – | – | – | +30.9% since Jun 2026 | +2x |
More about this table
Each fund’s return minus what its stated multiple would have produced over the same days, in percentage points, to Oct 27, 2026; largest first. What XBI itself did over the same days: −0.1% over one month, +3.4% over three months, +39.3% over one year.
Questions people ask
- Which 3x XBI ETFs are there?
- As of Oct 27, 2026, 1 ETF sets out to return 3x the daily move in biotech (XBI): LABU.
- Which 2x XBI ETFs are there?
- As of Oct 27, 2026, 1 ETF sets out to return 2x the daily move in biotech (XBI): XBIX.
- Which inverse XBI ETFs are there?
- As of Oct 27, 2026, 1 ETF sets out to return the opposite of the daily move in biotech (XBI), at −3x: LABD.
- Which XBI leveraged ETF is largest?
- LABU, Direxion Daily S&P Biotech Bull 3X ETF, at $586m in net assets on Oct 26, 2026, the largest of the 3 on XBI with a published size.
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ETFIQ, XBI leveraged and inverse ETFs, data as of Oct 27, 2026. https://etfiq.com/leverage/xbi-leveraged-etfs
ETFIQ. (Oct 27, 2026). XBI leveraged and inverse ETFs. Retrieved from https://etfiq.com/leverage/xbi-leveraged-etfs
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Every number dated. Not investment advice.