Data as of .
AIPO vs HLTH: which is really different?
AIPO and HLTH hold 0% of their weight in the same names.
ETFIQ Off-Index Score: HLTH scores higher
How much of it is not the index it is sold as an alternative to?
A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed
0% of the two portfolios are the same securities at the same weight.
What they hold in common
By the books each fund has filed, AIPO and HLTH hold 0% of their money in the same securities at the same weight.
| Only in AIPO | Only in HLTH |
|---|---|
| Eaton Corp Plc 8.31% | 10X GENOMICS INC 7.67% |
| Quanta Services Inc 8.25% | TWIST BIOSCIENCE CORP 6.52% |
| Ge Vernova Inc 8.03% | ILLUMINA INC 5.44% |
| Vertiv Holdings Co 6.56% | NATERA INC 5.11% |
| Bloom Energy Corp 5.10% | CYTOKINETICS INC 4.61% |
| Alphabet Inc 4.30% | INTUITIVE SURGICAL INC 4.36% |
| Nvidia Corp 4.04% | REVOLUTION MEDICINES INC 4.28% |
| Broadcom Inc 3.97% | VERTEX PHARMACEUTICALS INC 4.08% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026 and Sep 21, 2026.
Performance, window by window
| Window | Total return | vs the S&P 500 | vs the Nasdaq-100 | |||
|---|---|---|---|---|---|---|
| AIPO | HLTH | AIPO | HLTH | AIPO | HLTH | |
| 3 months | −16.1% | not published | −18.4 pts | not published | −13.7 pts | not published |
| 6 months | +15.1% | not published | −2.9 pts | not published | −9.1 pts | not published |
| 1 year | +29.3% | not published | +12.7 pts | not published | +7.5 pts | not published |
| Since launch | +40.1% | +15.8% | +18.9 pts | +13.7 pts | +12.1 pts | +14.0 pts |
| AIPO Defiance AI & Power Infrastructure ETF Holds 89 stocks in aI infrastructure and chips, 62% of its weight in S&P 500 companies | HLTH Tema Healthcare AI ETF Holds 32 stocks in artificial intelligence, 19% of its weight in S&P 500 companies | |
|---|---|---|
| Issuer | Defiance | Tema |
| Theme | AI infrastructure and chips | Artificial intelligence |
| In the S&P 500 | 61.8% | 19.2% |
| Active share vs the S&P 500 | 86.1% | 99.2% |
| In the Nasdaq-100 | 20.6% | 11.9% |
| Holdings | 89 | 32 |
| Top ten, share of the fund | 55.1% | 49.9% |
| Expense ratio | 0.69% | 0.75% |
| Fee for the differing part | 0.80% | 0.76% |
| Total return, 1 year | +29.3% | +15.8% (since launch on Jul 21, 2026) |
| vs the S&P 500 | +12.7 pts | +13.7 pts |
| vs the Nasdaq-100 | +7.5 pts | +14.0 pts |
| Below its high | −18.0% | −2.1% |
| Net assets | $915m | not published |
AIPO in plain words
By weight, 62% of AIPO's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 86%. The top ten holdings are 55% of the fund across 89 positions, as published by its issuer for Sep 21, 2026. Over the year to Sep 18, 2026 the fund returned +29.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 12.7 pts. It sits 18.0% below its all-time high of Jun 22, 2026.
HLTH in plain words
By weight, 19% of HLTH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 32 positions, as published by its issuer for Sep 18, 2026. Since it launched on Jul 21, 2026 the fund returned +15.8% with distributions reinvested against +2.0% for the S&P 500, so a holder was ahead by 13.7 pts.
Questions people ask
- Do AIPO and HLTH hold the same stocks?
- By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
- Which is more different from the S&P 500, AIPO or HLTH?
- AIPO has 62% of its weight in S&P 500 names and HLTH has 19%, so HLTH differs more from the index.
- Which is cheaper, AIPO or HLTH?
- AIPO charges 0.69% a year and HLTH charges 0.75%, so AIPO is cheaper. Fees come from each fund's prospectus.
Other comparisons
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, AIPO against HLTH, data as of Sep 18, 2026. https://etfiq.com/compare/themes/aipo-vs-hlth Free to use with attribution; the underlying files are at Open data.