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Data as of Sep 19, 2026.

ETFIQetfiq.com · independent ETF data

QIS vs VOO: how they differ

Over the year VOO returned more, +16.6% to QIS's −37.0%, and VOO charges 0.03% to QIS's 1.21%.

Simplify Multi-QIS Alternative ETF and Vanguard S&P 500 ETF.

QIS and VOO on the fields both publish, as of Sep 19, 2026. Source: ETFIQ.
QIS
Simplify Multi-QIS Alternative ETF
VOO
Vanguard S&P 500 ETF
Where it sitsAlternatives ETFCore fund
IssuerSimplifyVanguard
What it isMulti-strategyTracks the S&P 500
Total return, 1 year−37.0%+16.6%
S&P 500 over the same days+16.6%+16.6%
Gap to the S&P 500−53.5 pts0.0 pts
Expense ratio1.21%0.03%
Holdingsnot filed508
Net assets$46m$1000.0bn

QIS in plain words

QIS is a multi-strategy fund. ETFIQ measures what every alternatives fund is sold on: whether it moves differently from the stock market. Over the year to Sep 18, 2026, its weekly returns had a correlation of −0.15 with the S&P 500’s and a beta of −0.49, so for each 1% the index moved it moved about 0.49% the other way. The S&P 500 fell in 22 of those 52 weeks, by 1.24% on average. In the same weeks QIS fell 0.74% on average, a down-week capture of 59.6%. Over the same 52 weeks QIS returned −37.8% and a Treasury bill fund +3.6%, so it finished 41.5 percentage points behind cash.

VOO in plain words

VOO tracks the S&P 500. Over the year to Sep 18, 2026 it returned +16.6% with distributions reinvested, against +16.6% for the S&P 500 and +21.8% for the Nasdaq-100. The prospectus expense ratio is 0.03% a year. By its holdings published by its issuer as of Aug 31, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 508 positions, with the top ten at 37.8%.

Questions people ask

Which returned more over the last year, QIS or VOO?
In the year to Sep 19, 2026, with distributions reinvested, QIS returned −37.0% and VOO returned +16.6%, so VOO returned more.
Which is cheaper, QIS or VOO?
QIS charges 1.21% a year and VOO charges 0.03%, so VOO is cheaper. Fees come from each fund's prospectus.
Are QIS and VOO the same kind of fund?
No. QIS is an alternatives ETF and VOO is an index ETF, so they are built for different jobs. The table compares what both publish: return, cost and what each actually holds.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

QIS against VOO, ETFIQ, data as of Sep 19, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, QIS against VOO, data as of Sep 19, 2026. https://etfiq.com/compare/any/qis-vs-voo Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources