Data as of Oct 28, 2026.

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Across categories

IBB vs SPYD: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to SPYD's +15.3%, and SPYD charges 0.07% to IBB's 0.44%.

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Net assets on Oct 27, 2026: $11.0bn for iShares Biotechnology ETF and $7.5bn for State Street SPDR Portfolio S&P 500 High Dividend ETF.

At a glance
+37.5%
IBB total return, 1 year
+15.3%
SPYD total return, 1 year
0.44%
IBB expense ratio
0.07%
SPYD expense ratio

Pair scorecard

SPYD costs 0.37 points a year less; their one-year returns differ by 22.2 points; IBB is 1.5 times larger.

IBB vs SPYD: Differences, Returns & Fees
MeasureIBBSPYD
Return
Total return, 1 year+37.5%+15.3%
Drawdown
Below its high4.1%, high on Aug 24, 2026
Benchmark
What it tracksBiotechS&P 500 High Dividend Index
Cost and size
Expense ratio0.44%0.07%
Net assets, as of Oct 27, 2026$11.0bn$7.5bn
Holdings
Holdings in common0%
Top ten holdings, share of the fund50%16.1%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and SPYD hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB SPYD
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in SPYD
ACCENTURE PLC CL A 2.18%
HP INC 1.74%
HASBRO INC 1.73%
PFIZER INC 1.56%
CHEVRON CORP 1.54%
MEDTRONIC PLC 1.49%
CROWN CASTLE INC 1.47%
BEST BUY CO INC 1.47%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF SPYD State Street SPDR Portfolio S&P 500 High Dividend ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the S&P 500 High Dividend
Total return, 1 year +37.5% +15.3%
Expense ratio 0.44% 0.07%
Already in the S&P 500 40.2% 99.3%
Holdings 245 79
Net assets, as of Oct 27, 2026 $11.0bn $7.5bn

IBB and SPYD on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

SPYD

SPYD tracks the S&P 500 High Dividend. Over the year to Oct 28, 2026 it returned +15.3% with distributions reinvested. The prospectus expense ratio is 0.07% a year. By its holdings published by its issuer for Oct 27, 2026, 99% of the fund by weight is stocks the S&P 500 also holds, across 79 positions, with the top ten at 16.1%. It sat 4.1% below its high of Aug 24, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and SPYD in the same category?
IBB is a thematic ETF and SPYD is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or SPYD?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and SPYD +15.3%.
Which is cheaper, IBB or SPYD?
SPYD is cheaper, by 0.37 percentage points a year. That is about $37 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and SPYD overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 99% of SPYD by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against SPYD, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-spyd

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