Data as of Oct 28, 2026.

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FXH vs IHE: Differences, Returns & Fees

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Over the year to Oct 28, 2026, FXH returned +21.5% to IHE's +41.9%; 13% of their weight is in the same names.

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Net assets on Oct 27, 2026: $1.1bn for First Trust Health Care AlphaDEX Fund and $1.6bn for iShares U.S. Pharmaceuticals ETF.

At a glance
+21.5%
FXH total return, 1 year
+41.9%
IHE total return, 1 year
0.61%
FXH expense ratio
0.37%
IHE expense ratio

Pair scorecard

IHE costs 0.24 points a year less; their one-year returns differ by 20.4 points; IHE is 1.5 times larger.

FXH vs IHE: Differences, Returns & Fees
MeasureFXHIHE
Return
Total return, 1 year+21.5%+41.9%
Drawdown
Below its high3.9%, high on Aug 19, 2026
Benchmark
What it tracksStrataQuant Health Care IndexDow Jones U.S. Select Pharmaceuticals Index
Cost and size
Expense ratio0.61%0.37%
Net assets, as of Oct 27, 2026$1.1bn$1.6bn
Holdings
Holdings in common13%
Top ten holdings, share of the fund24.7%80.4%

Holdings in common uses holdings dated Oct 27, 2026. Method

Risk and return

May 18, 2007 to Oct 23, 2026 · 1,014 weekly returns
FXH IHE
Return
Total return edge Tie +601.0% +603.4%
Annualized edge Tie +10.5% +10.5%
Price return edge FXH +581.6% +426.0%
Risk
Volatility edge Tie 18.5% 18.6%
Max drawdown edge IHE −41.9% −36.6%
Risk-adjusted
Sharpe edge Tie 0.55 0.55
Sortino edge Tie 0.77 0.79
Calmar edge IHE 0.25 0.29
Reading

FXH and IHE returned about the same: +601.0% and +603.4%. FXH and IHE swung about the same: 18.5% and 18.6%. IHE fell less at its worst: −36.6% to −41.9%.

Full scorecard

9 measures, with how each is measured
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Risk and return: FXH vs IHE: Differences, Returns & Fees
MeasureFXHIHEEdgeHow it is measured
Return
Total return+601.0%+603.4%TiePrice change plus distributions, reinvested.
Annualized+10.5%+10.5%TieTotal return as a yearly rate.
Price return+581.6%+426.0%FXHPrice change alone, distributions left out.
Risk
Volatility18.5%18.6%TieSpread of weekly returns, annualized. Lower is steadier.
Downside deviation13.2%13.0%TieLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−41.9%−36.6%IHEDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.550.55TieReturn above Treasury bills per unit of volatility.
Sortino0.770.79TieReturn above Treasury bills per unit of downside deviation.
Calmar0.250.29IHEAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,014 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

13%

By the books each fund has filed, FXH and IHE hold 13% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

13% in common

Positions both hold · largest shared weight first FXH IHE
Zoetis Inc. 2.06% 4.73%
Eli Lilly and Company 2.04% 25.28%
Bristol-Myers Squibb Company 1.82% 4.24%
Corcept Therapeutics Inc. 1.75% 1.81%
Jazz Pharmaceuticals Plc 1.64% 2.91%
Viatris Inc. 1.36% 4.67%
Pfizer Inc. 0.96% 4.76%
Axsome Therapeutics, Inc. 0.71% 1.37%
Johnson & Johnson 0.44% 22.31%
Elanco Animal Health Incorporated 0.43% 2.46%
Only in one fund ↓
Only in FXH
Halozyme Therapeutics, Inc. 2.68%
Centene Corporation 2.55%
Caris Life Sciences, Inc. 2.53%
The Cigna Group 2.53%
Globus Medical, Inc. (Class A) 2.49%
Zimmer Biomet Holdings, Inc. 2.49%
Medpace Holdings, Inc. 2.48%
Universal Health Services, Inc. (Class B) 2.34%
Only in IHE
ROYALTY PHARMA PLC CLASS A 4.78%
MERCK & CO INC 4.26%
LIGAND PHARMACEUTICALS 1.35%
DEFINIUM THERAPEUTICS INC 1.08%
VERADERMICS 0.96%
INDIVIOR PHARMACEUTICALS INC 0.89%
AMNEAL PHARMACEUTICALS INC CLASS A 0.86%
ORGANON 0.78%
Check overlap with more funds →

Side by side

FXH First Trust Health Care AlphaDEX Fund IHE iShares U.S. Pharmaceuticals ETF
Where it sits Stock ETF Stock ETF
What it is Tracks an index Tracks an index
Total return, 1 year +21.5% +41.9%
Expense ratio 0.61% 0.37%
Already in the S&P 500 59.2% 65.5%
Holdings 72 54
Net assets, as of Oct 27, 2026 $1.1bn $1.6bn

FXH and IHE on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-6F111B9361

FXH and IHE are built for the same job. How do they differ in cost, holdings and results?

  1. What each follows. FXH follows StrataQuant Health Care Index and IHE follows Dow Jones U.S. Select Pharmaceuticals Index.
  2. Holdings in common. 13% of the weight is in the same securities (holdings dated Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 FXH returned +21.5% and IHE +41.9% with distributions reinvested, a gap of 20.4 points.

Data as of Oct 28, 2026.

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About each fund
FXH

FXH tracks an index. Over the year to Oct 28, 2026 it returned +21.5% with distributions reinvested. The prospectus expense ratio is 0.61% a year. By its holdings published by its issuer for Oct 27, 2026, 59% of the fund by weight is stocks the S&P 500 also holds, across 72 positions, with the top ten at 24.7%.

IHE

IHE tracks an index. Over the year to Oct 28, 2026 it returned +41.9% with distributions reinvested. The prospectus expense ratio is 0.37% a year. By its holdings published by its issuer for Oct 27, 2026, 66% of the fund by weight is stocks the S&P 500 also holds, across 54 positions, with the top ten at 80.4%. It sat 3.9% below its high of Aug 19, 2026 on Oct 28, 2026.

Questions people ask

Which returned more over the last year, FXH or IHE?
In the year to Oct 28, 2026, with distributions reinvested, FXH returned +21.5% and IHE +41.9%.
Which is cheaper, FXH or IHE?
IHE is cheaper, by 0.24 percentage points a year. That is about $24 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do FXH and IHE overlap with the S&P 500?
By their latest filed holdings, 59% of FXH and 66% of IHE by weight is stocks the S&P 500 already holds.
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ETFIQ, FXH against IHE, data as of Oct 28, 2026. https://etfiq.com/compare/any/fxh-vs-ihe

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