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Data as of Nov 4, 2026.

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Thematic ETFs

HLTH vs WISE: Holdings Overlap & Returns

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HLTH and WISE hold 0% of their weight in the same names.

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Net assets: $12m on Nov 3, 2026 for Tema Healthcare AI ETF, and $22m on Nov 4, 2026 for Themes Generative Artificial Intelligence ETF.

HLTH on its own →WISE on its own →
At a glance
23.9%
HLTH in the S&P 500
30.1%
WISE in the S&P 500
+13.6%
HLTH total return, since launch, Jul 21, 2026
−29.1%
WISE total return, 1 year
HLTH · 3 months to Nov 4, 2026 76% of its weight is outside the S&P 500
76% of its weight is outside the S&P 50024% of HLTH's weight is in S&P 500 companies and 76% is outside the index. Holdings as of Nov 3, 2026.24%76%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 50% of the fund · 32 holdings as published by its issuer for Nov 3, 2026 · Nasdaq-100: 15% in76% of its weight is outside the S&P 50024% of HLTH's weight is in S&P 500 companies and 76% is outside the index. Holdings as of Nov 3, 2026.24%76%inoutside the S&P 500active share 99% · Nasdaq-100: 15% in

24% of HLTH's weight is in S&P 500 companies and 76% is outside the index. Holdings as of Nov 3, 2026.

WISE · 1 year to Nov 4, 2026 70% of its weight is outside the S&P 500
70% of its weight is outside the S&P 50030% of WISE's weight is in S&P 500 companies and 70% is outside the index. Holdings as of Nov 4, 2026.30%70%in the S&P 500of its weight outside the S&P 500active share 83% · top ten 49% of the fund · 41 holdings as published by its issuer for Nov 4, 2026 · Nasdaq-100: 28% in70% of its weight is outside the S&P 50030% of WISE's weight is in S&P 500 companies and 70% is outside the index. Holdings as of Nov 4, 2026.30%70%inoutside the S&P 500active share 83% · Nasdaq-100: 28% in

30% of WISE's weight is in S&P 500 companies and 70% is outside the index. Holdings as of Nov 4, 2026.

Pair scorecard

WISE costs 0.40 points a year less; WISE is 1.8 times larger.

Points (pts) are percentage points.

HLTH vs WISE: Holdings Overlap & Returns
MeasureHLTHWISE
Return
Total return, 1 yearnot published−29.1%
Drawdown
Below its all-time high5.9%, high on Oct 5, 202634.2%, high on Oct 15, 2025
Against its benchmark
What it tracksArtificial intelligenceArtificial intelligence
Its benchmark, total return, 1 year+15.0%
Against its benchmark, 1 yearbehind by 44.1 pts
Cost and size
Expense ratio0.75%0.35%
Net assets, as of Nov 3, 2026$12m$22m
Holdings
Holdings in common0%

Method

What they share

0%

By the books each fund has filed, HLTH and WISE hold 0% of their money in the same securities at the same weight. Holdings dated Nov 3, 2026 and Nov 4, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first HLTH WISE
Only in one fund ↓
Only in HLTH
10X GENOMICS INC 5.87%
INTUITIVE SURGICAL INC 5.82%
REVOLUTION MEDICINES INC 5.06%
NATERA INC 4.98%
THERMO FISHER SCIENTIFIC INC 4.92%
TWIST BIOSCIENCE CORP 4.86%
CYTOKINETICS INC 4.84%
VERTEX PHARMACEUTICALS INC 4.70%
Only in WISE
Information Services Group Inc 6.06%
NVIDIA Corp 5.47%
Caris Life Sciences Inc 5.24%
Advanced Micro Devices Inc 5.21%
C3.ai Inc 5.12%
Snowflake Inc 5.01%
Palantir Technologies Inc 4.59%
Alphabet Inc 4.26%
Check overlap with more funds →

Window by window

Window by window: HLTH vs WISE: Holdings Overlap & Returns
Total returnvs its benchmark
WindowHLTHWISEHLTHWISE
3 months+7.7%−18.0%not measured−16.7 pts vs ACWI
6 months–−23.6%–−26.2 pts vs ACWI
1 year–−29.1%–−44.1 pts vs ACWI
Since launchNot the same days: HLTH Jul 2026 · WISE Dec 2023+13.6%+23.6%not measured−45.1 pts vs ACWI

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Side by side

HLTH Tema Healthcare AI ETF · Holds 32 stocks in artificial intelligence, 24% of its weight in S&P 500 companies WISE Themes Generative Artificial Intelligence ETF · Holds 41 stocks in artificial intelligence, 30% of its weight in S&P 500 companies
Issuer Tema Themes
Theme Artificial intelligence Artificial intelligence
In the S&P 500 23.9% 30.1%
Active share vs the S&P 500 99.2% 83.3%
In the Nasdaq-100 14.6% 27.8%
Holdings 32 41
Top ten, share of the fund 50.1% 49.2%
Expense ratio 0.75% 0.35%
Fee for the differing part 0.76% 0.42%
Total return, 1 year +13.6% (since launch, Jul 21, 2026) −29.1%
vs its benchmark not measured −44.1 pts vs ACWI
Below its high −5.9% −34.2%
Net assets, HLTH as of Nov 3, 2026 and WISE as of Nov 4, 2026 $12m $22m

As of Nov 4, 2026. Source: ETFIQ.

0% of the two portfolios are the same securities at the same weight.

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About each fund
HLTH

By weight, 24% of HLTH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 32 positions, as published by its issuer for Nov 3, 2026. Since it first traded on Jul 21, 2026 the fund returned +13.6% with distributions reinvested. It sits 5.9% below its all-time high of Oct 5, 2026.

WISE

By weight, 30% of WISE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 83%. The top ten holdings are 49% of the fund across 41 positions, as published by its issuer for Nov 4, 2026. Over the year to Nov 4, 2026 the fund returned −29.1% with distributions reinvested against +15.0% for its benchmark, the MSCI ACWI Index, so a holder was behind by 44.1 pts. It sits 34.2% below its all-time high of Oct 15, 2025.

Questions people ask

Do HLTH and WISE hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, HLTH or WISE?
HLTH has 24% of its weight in S&P 500 names and WISE has 30%, so HLTH differs more from the index.
Which is cheaper, HLTH or WISE?
HLTH charges 0.75% a year and WISE charges 0.35%, so WISE is cheaper. Fees come from each fund's prospectus.
Other comparisons
HLTH vs WDRNHLTH vs AIEQHLTH vs KAITHLTH vs AIUPWISE vs AGIQWISE vs XAWISE vs AINTWISE vs AIUP
Where to next
All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →HLTH on its own →WISE on its own →HLTH holdings →WISE dividend history →WISE holdings →Method →Standards and sources →
Sources and dates
HLTH filings on SEC EDGAR ↗
HLTH prospectus with the expense ratio (SEC) ↗
Tema page for HLTH ↗
WISE filings on SEC EDGAR ↗
WISE prospectus with the expense ratio (SEC) ↗
Themes page for WISE ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

Cite this pageCitation, APA and Markdown

ETFIQ, HLTH against WISE, data as of Nov 4, 2026. https://etfiq.com/compare/themes/hlth-vs-wise

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.