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Data as of .

AIX vs HLTH: which is really different?

AIX and HLTH hold 0% of their weight in the same names.

Defiance US 100 Tech AI Moat ETF and Tema Healthcare AI ETF.

88.0%AIX in the S&P 500
19.2%HLTH in the S&P 500
−4.6%AIX total return, 1 year
+15.8%HLTH total return, 1 year

ETFIQ Off-Index Score: HLTH scores higher

How much of it is not the index it is sold as an alternative to?

AIX 2HLTH 65.80.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

AIX12% of its weight is outside the S&P 500 · since launch to Sep 18, 2026
88%12%of its weight in S&P 500 companiesoutsideactive share 64% · top ten 53% of the fund · 32 holdings filed Sep 21, 2026 · Nasdaq-100: 94% in88%12%of its weight in S&P 500 companies12% of its weight outside the S&P 500active share 64% · top ten 53% of the fund
HLTH81% of its weight is outside the S&P 500 · since launch to Sep 18, 2026
19%81%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 50% of the fund · 32 holdings filed Sep 18, 2026 · Nasdaq-100: 12% in19%81%inoutside the S&P 500active share 99% · top ten 50% of the fund

0% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, AIX and HLTH hold 0% of their money in the same securities at the same weight.

Only in each
Only in AIXOnly in HLTH
Palantir Technologies Inc 6.26%10X GENOMICS INC 7.67%
Microsoft Corp 5.73%TWIST BIOSCIENCE CORP 6.52%
Advanced Micro Devices Inc 5.69%ILLUMINA INC 5.44%
Meta Platforms Inc 5.38%NATERA INC 5.11%
Apple Inc 5.30%CYTOKINETICS INC 4.61%
Micron Technology Inc 5.27%INTUITIVE SURGICAL INC 4.36%
Nvidia Corp 5.07%REVOLUTION MEDICINES INC 4.28%
Amazon.com Inc 4.84%VERTEX PHARMACEUTICALS INC 4.08%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026 and Sep 21, 2026.

Performance, window by window

AIX and HLTH over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
AIXHLTHAIXHLTHAIXHLTH
Since launch−4.6%+15.8%−6.9 pts+13.7 pts−2.6 pts+14.0 pts
Open the live comparison on ETFIQ
AIX and HLTH on the same fields, as of Sep 18, 2026. Source: ETFIQ.
AIX
Defiance US 100 Tech AI Moat ETF
Holds 32 stocks in artificial intelligence, 88% of its weight in S&P 500 companies
HLTH
Tema Healthcare AI ETF
Holds 32 stocks in artificial intelligence, 19% of its weight in S&P 500 companies
IssuerDefianceTema
ThemeArtificial intelligenceArtificial intelligence
In the S&P 50088.0%19.2%
Active share vs the S&P 50064.0%99.2%
In the Nasdaq-10094.3%11.9%
Holdings3232
Top ten, share of the fund52.9%49.9%
Expense ratio0.65%0.75%
Fee for the differing part1.02%0.76%
Total return, 1 year−4.6% (since launch on Jun 30, 2026)+15.8% (since launch on Jul 21, 2026)
vs the S&P 500−6.9 pts+13.7 pts
vs the Nasdaq-100−2.6 pts+14.0 pts
Below its high−4.6%−2.1%
Net assets$482,327not published

AIX in plain words

By weight, 88% of AIX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 64%. The top ten holdings are 53% of the fund across 32 positions, as published by its issuer for Sep 21, 2026. Since it launched on Jun 30, 2026 the fund returned −4.6% with distributions reinvested against +2.3% for the S&P 500, so a holder was behind by 6.9 pts.

HLTH in plain words

By weight, 19% of HLTH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 32 positions, as published by its issuer for Sep 18, 2026. Since it launched on Jul 21, 2026 the fund returned +15.8% with distributions reinvested against +2.0% for the S&P 500, so a holder was ahead by 13.7 pts.

Questions people ask

Do AIX and HLTH hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, AIX or HLTH?
AIX has 88% of its weight in S&P 500 names and HLTH has 19%, so HLTH differs more from the index.
Which is cheaper, AIX or HLTH?
AIX charges 0.65% a year and HLTH charges 0.75%, so AIX is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

AIX against HLTH, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, AIX against HLTH, data as of Sep 18, 2026. https://etfiq.com/compare/themes/aix-vs-hlth Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources