Data as of Oct 28, 2026.

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VO vs XLV: Differences, Returns & Fees

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Over the year to Oct 28, 2026, VO returned +12.8% to XLV's +25.6%; 9% of their weight is in the same names.

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Net assets: $103.4bn on Sep 30, 2026 for Vanguard Morningstar Mid-Cap ETF, and $47.0bn on Oct 27, 2026 for State Street Health Care Select Sector SPDR ETF.

At a glance
+12.8%
VO total return, 1 year
+25.6%
XLV total return, 1 year
0.03%
VO expense ratio
0.08%
XLV expense ratio

Pair scorecard

VO costs 0.05 points a year less; their one-year returns differ by 12.8 points; VO is 2.4 times larger.

VO vs XLV: Differences, Returns & Fees
MeasureVOXLV
Return
Total return, 1 year+12.8%+25.6%
Drawdown
Below its high3.1%, high on Aug 14, 2026
Benchmark
What it tracksMorningstar US Mid Cap Index (formerly CRSP US Mid Cap Index)Health Care Select Sector Index
Cost and size
Expense ratio0.03%0.08%
Net assets, as of Sep 30, 2026$103.4bn$43.4bn
Holdings
Holdings in common9%
Top ten holdings, share of the fund9.7%60.6%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

9%

By the books each fund has filed, VO and XLV hold 9% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

9% in common

Positions both hold · largest shared weight first VO XLV
Cencora Inc 0.54% 0.95%
Cardinal Health Inc 0.51% 0.88%
Edwards Lifesciences Corp 0.49% 0.81%
Becton Dickinson & Co 0.48% 0.82%
Agilent Technologies Inc 0.48% 0.77%
Humana Inc 0.45% 0.77%
IQVIA Holdings Inc 0.44% 0.69%
Waters Corp 0.43% 0.71%
Veeva Systems Inc 0.41% 0.72%
IDEXX Laboratories Inc 0.41% 0.68%
Regeneron Pharmaceuticals Inc 0.38% 1.23%
Moderna Inc 0.34% 1.19%
Only in one fund ↓
Only in VO
Cloudflare Inc 1.11%
Valero Energy Corp 1.10%
Marathon Petroleum Corp 1.10%
Phillips 66 1.01%
Quanta Services Inc 0.95%
Vertiv Holdings Co 0.92%
Datadog Inc 0.91%
Howmet Aerospace Inc 0.89%
Only in XLV
ELI LILLY + CO 15.77%
JOHNSON + JOHNSON 9.96%
ABBVIE INC 7.78%
UNITEDHEALTH GROUP INC 5.66%
MERCK + CO. INC. 5.38%
THERMO FISHER SCIENTIFIC INC 3.94%
AMGEN INC 3.72%
GILEAD SCIENCES INC 3.03%
Check overlap with more funds →

Side by side

VO Vanguard Morningstar Mid-Cap ETF XLV State Street Health Care Select Sector SPDR ETF
Where it sits Stock ETF Stock ETF
What it is Tracks an index of Mid-Cap Tracks an index of Health care
Total return, 1 year +12.8% +25.6%
Expense ratio 0.03% 0.08%
Already in the S&P 500 91.1% 99.7%
Holdings 273 62
Net assets, VO as of Sep 30, 2026 and XLV as of Oct 27, 2026 $103.4bn $47.0bn

VO and XLV on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
VO

VO tracks an index of Mid-Cap. Over the year to Oct 28, 2026 it returned +12.8% with distributions reinvested. The prospectus expense ratio is 0.03% a year. By its holdings published by its issuer as of Sep 30, 2026, 91% of the fund by weight is stocks the S&P 500 also holds, across 273 positions, with the top ten at 9.7%. It sat 3.1% below its high of Aug 14, 2026 on Oct 28, 2026.

XLV

XLV tracks an index of Health care. Over the year to Oct 28, 2026 it returned +25.6% with distributions reinvested. The prospectus expense ratio is 0.08% a year. By its holdings published by its issuer for Oct 27, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 62 positions, with the top ten at 60.6%.

Questions people ask

Which returned more over the last year, VO or XLV?
In the year to Oct 28, 2026, with distributions reinvested, VO returned +12.8% and XLV +25.6%.
Which is cheaper, VO or XLV?
VO is cheaper, by 0.05 percentage points a year. That is about $5 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do VO and XLV overlap with the S&P 500?
By their latest filed holdings, 91% of VO and 100% of XLV by weight is stocks the S&P 500 already holds.
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ETFIQ, VO against XLV, data as of Oct 28, 2026. https://etfiq.com/compare/any/vo-vs-xlv

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