Data as of Oct 28, 2026.
IBB vs VXUS: Differences, Returns & Fees
Over the year to Oct 28, 2026, IBB returned +37.5% to VXUS's +13.8%, and VXUS charges 0.05% to IBB's 0.44%.
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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $163.2bn on Sep 30, 2026 for Vanguard Total International Stock ETF.
Pair scorecard
VXUS costs 0.39 points a year less; their one-year returns differ by 23.7 points; VXUS is 14.6 times larger.
| Measure | IBB | VXUS |
|---|---|---|
| Return | ||
| Total return, 1 year | +37.5% | +13.8% |
| Drawdown | ||
| Below its high | 5.1%, high on Sep 4, 2026 | |
| Benchmark | ||
| What it tracks | Biotech | FTSE Global All Cap ex US Index |
| Cost and size | ||
| Expense ratio | 0.44% | 0.05% |
| Net assets, as of Sep 30, 2026 | $11.2bn | $163.2bn |
| Active share vs the S&P 500 | 99% | |
| Holdings | ||
| Holdings in common | 0% | |
| Top ten holdings, share of the fund | 50% | 14.6% |
Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method
What they share
By the books each fund has filed, IBB and VXUS hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.
half
0% in common
Only in one fund ↓
Side by side
IBB and VXUS on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.
IBB
By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.
VXUS
VXUS tracks an index of Total International Stock. Over the year to Oct 28, 2026 it returned +13.8% with distributions reinvested. The prospectus expense ratio is 0.05% a year. By its holdings published by its issuer as of Sep 30, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 8,913 positions, with the top ten at 14.6%. It sat 5.1% below its high of Sep 4, 2026 on Oct 28, 2026.
Questions people ask
- Are IBB and VXUS in the same category?
- IBB is a thematic ETF and VXUS is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
- Which returned more over the last year, IBB or VXUS?
- In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VXUS +13.8%.
- Which is cheaper, IBB or VXUS?
- VXUS is cheaper, by 0.39 percentage points a year. That is about $39 on $10,000 held for a year. Fees come from each fund's prospectus.
Links are sources, not endorsements. A comparison is not a recommendation.
How this is computed
Overlap adds up the smaller of the two weights for each security both funds hold.
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ETFIQ, IBB against VXUS, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vxus
ETFIQ. (Oct 28, 2026). IBB against VXUS. Retrieved from https://etfiq.com/compare/any/ibb-vs-vxus
[IBB against VXUS (ETFIQ, Oct 28, 2026)](https://etfiq.com/compare/any/ibb-vs-vxus)
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