Data as of Oct 28, 2026.

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Across categories

IBB vs VTEB: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VTEB's −0.4%, and VTEB charges 0.03% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $49.6bn on Sep 30, 2026 for Vanguard Tax-Exempt Bond ETF.

At a glance
+37.5%
IBB total return, 1 year
−0.4%
VTEB total return, 1 year
0.44%
IBB expense ratio
0.03%
VTEB expense ratio

Pair scorecard

VTEB costs 0.41 points a year less; their one-year returns differ by 37.9 points; VTEB is 4.4 times larger.

IBB vs VTEB: Differences, Returns & Fees
MeasureIBBVTEB
Return
Total return, 1 year+37.5%−0.4%
Benchmark
What it tracksBiotechS&P National AMT-Free Municipal Bond Index
Cost and size
Expense ratio0.44%0.03%
Net assets, as of Sep 30, 2026$11.2bn$49.6bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
In the S&P 500, by weight40%
Top ten holdings, share of the fund50%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and VTEB hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB VTEB
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in VTEB
Vanguard Municipal Low Duration Fund 0.69%
State of California 0.15%
State of California 0.14%
New York State Dormitory Authority 0.13%
State of Illinois 0.12%
Ohio State University 0.12%
City of New York NY 0.10%
State of Wisconsin 0.10%
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Side by side

IBB iShares Biotechnology ETF VTEB Vanguard Tax-Exempt Bond ETF
Where it sits Thematic ETF Bond ETF
What it is Biotech Tracks an index of Tax-Exempt Bond
Total return, 1 year +37.5% −0.4%
Expense ratio 0.44% 0.03%
Holdings 245 11155
Net assets, IBB as of Oct 27, 2026 and VTEB as of Sep 30, 2026 $11.0bn $49.6bn

IBB and VTEB on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VTEB

VTEB tracks an index of Tax-Exempt Bond. Over the year to Oct 28, 2026 it returned −0.4% with distributions reinvested. The prospectus expense ratio is 0.03% a year.

Questions people ask

Are IBB and VTEB in the same category?
IBB is a thematic ETF and VTEB is a bond ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VTEB?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VTEB −0.4%.
Which is cheaper, IBB or VTEB?
VTEB is cheaper, by 0.41 percentage points a year. That is about $41 on $10,000 held for a year. Fees come from each fund's prospectus.
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ETFIQ, IBB against VTEB, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vteb

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