Data as of Oct 28, 2026.

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IBB vs SPSB: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to SPSB's +2.2%, and SPSB charges 0.04% to IBB's 0.44%.

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Net assets on Oct 27, 2026: $11.0bn for iShares Biotechnology ETF and $11.3bn for State Street SPDR Portfolio Short Term Corporate Bond ETF.

At a glance
+37.5%
IBB total return, 1 year
+2.2%
SPSB total return, 1 year
0.44%
IBB expense ratio
0.04%
SPSB expense ratio

Pair scorecard

SPSB costs 0.40 points a year less; their one-year returns differ by 35.3 points.

IBB vs SPSB: Differences, Returns & Fees
MeasureIBBSPSB
Return
Total return, 1 year+37.5%+2.2%
Benchmark
What it tracksBiotechBloomberg U.S. 1-3 Year Corporate Bond Index
Cost and size
Expense ratio0.44%0.04%
Net assets, as of Oct 27, 2026$11.0bn$11.3bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
In the S&P 500, by weight40%
Top ten holdings, share of the fund50%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and SPSB hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB SPSB
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in SPSB
SALESFORCE INC SR UNSECURED 03/29 4.65 0.66%
AERCAP IRELAND CAP/GLOBA COMPANY GUAR 10/28 3 0.47%
PFIZER INVESTMENT ENTER COMPANY GUAR 05/28 4.45 0.45%
AMAZON.COM INC SR UNSECURED 03/29 4 0.45%
BANK OF AMERICA CORP SR UNSECURED 12/28 VAR 0.45%
NVIDIA CORP SR UNSECURED 06/29 4.35 0.43%
GOLDMAN SACHS GROUP INC SR UNSECURED 05/29 VAR 0.38%
ORACLE CORP SR UNSECURED 02/29 4.55 0.37%
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Side by side

IBB iShares Biotechnology ETF SPSB State Street SPDR Portfolio Short Term Corporate Bond ETF
Where it sits Thematic ETF Bond ETF
What it is Biotech Tracks an index of Short Term Corporate Bond
Total return, 1 year +37.5% +2.2%
Its benchmark over the same days not measured −1.4% (AGG)
Gap to its benchmark not measured +3.6 pts vs AGG
Expense ratio 0.44% 0.04%
Holdings 245 1684
Net assets, as of Oct 27, 2026 $11.0bn $11.3bn

IBB and SPSB on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

SPSB

SPSB tracks an index of Short Term Corporate Bond. Over the year to Oct 28, 2026 it returned +2.2% with distributions reinvested, against −1.4% for its benchmark, the Bloomberg U.S. Aggregate Bond Index. The prospectus expense ratio is 0.04% a year.

Questions people ask

Are IBB and SPSB in the same category?
IBB is a thematic ETF and SPSB is a bond ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or SPSB?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and SPSB +2.2%.
Which is cheaper, IBB or SPSB?
SPSB is cheaper, by 0.40 percentage points a year. That is about $40 on $10,000 held for a year. Fees come from each fund's prospectus.
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ETFIQ, IBB against SPSB, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-spsb

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