Data as of Oct 28, 2026.

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IBB vs IEFA: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to IEFA's +12.3%, and IEFA charges 0.07% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $190.4bn on Oct 28, 2026 for iShares Core MSCI EAFE ETF.

At a glance
+37.5%
IBB total return, 1 year
+12.3%
IEFA total return, 1 year
0.44%
IBB expense ratio
0.07%
IEFA expense ratio

Pair scorecard

IEFA costs 0.37 points a year less; their one-year returns differ by 25.2 points; IEFA is 17.3 times larger.

IBB vs IEFA: Differences, Returns & Fees
MeasureIBBIEFA
Return
Total return, 1 year+37.5%+12.3%
Drawdown
Below its high4.7%, high on Aug 25, 2026
Benchmark
What it tracksBiotechMSCI EAFE IMI Index
Cost and size
Expense ratio0.44%0.07%
Net assets, as of Oct 27, 2026$11.0bn$190.1bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
Top ten holdings, share of the fund50%12.3%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and IEFA hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB IEFA
ARGENX SE ADR 3.42% 0.22%
GENMAB SPONSORED ADR 1.72% 0.11%
ABIVAX AMERICAN DEPOSITARY SHARES 0.44% 0.02%
EMERGENT BIOSOLUTIONS 0.02% 0.15%
LAKEFRONT BIOTHERAPEUTICS ADR NV 0.10% 0.01%
ACADIA PHARMACEUTICALS 0.24% 0.00%
AKERO THERAPEUTICS CVR 0.00% 0.01%
AURA BIOSCIENCES 0.03% 0.00%
CARIS LIFE SCIENCES 0.30% 0.00%
CHARLES RIVER LABORATORIES INTERNA 1.18% 0.00%
PHARVARIS N V 0.07% 0.00%
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ILLUMINA INC 2.93%
BIOGEN 2.58%
Only in IEFA
ASML HOLDING 2.55%
ROCHE PS PAR AG 1.36%
SHELL 1.21%
HSBC HOLDINGS PLC 1.18%
NOVARTIS AG 1.14%
ASTRAZENECA PLC 1.04%
NESTLE SA 1.04%
SAP 0.97%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF IEFA iShares Core MSCI EAFE ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the MSCI EAFE
Total return, 1 year +37.5% +12.3%
Its benchmark over the same days not measured +14.3% (ACWX)
Gap to its benchmark not measured −2.0 pts vs ACWX
Expense ratio 0.44% 0.07%
Already in the S&P 500 40.2% 0.0%
Holdings 245 2629
Net assets, IBB as of Oct 27, 2026 and IEFA as of Oct 28, 2026 $11.0bn $190.4bn

IBB and IEFA on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

IEFA

IEFA tracks the MSCI EAFE. Over the year to Oct 28, 2026 it returned +12.3% with distributions reinvested, against +14.3% for its benchmark, the MSCI ACWI ex USA Index. The prospectus expense ratio is 0.07% a year. By its holdings published by its issuer for Oct 27, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 2,629 positions, with the top ten at 12.3%. It sat 4.7% below its high of Aug 25, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and IEFA in the same category?
IBB is a thematic ETF and IEFA is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or IEFA?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and IEFA +12.3%.
Which is cheaper, IBB or IEFA?
IEFA is cheaper, by 0.37 percentage points a year. That is about $37 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and IEFA overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 0% of IEFA by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, IBB against IEFA, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-iefa

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