Data as of Oct 28, 2026.

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FTXH vs XLV: Differences, Returns & Fees

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Over the year to Oct 28, 2026, FTXH returned +47.9% to XLV's +25.6%; 45% of their weight is in the same names.

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Net assets on Oct 27, 2026: $1.2bn for First Trust Nasdaq Pharmaceuticals ETF and $47.0bn for State Street Health Care Select Sector SPDR ETF.

At a glance
+47.9%
FTXH total return, 1 year
+25.6%
XLV total return, 1 year
0.60%
FTXH expense ratio
0.08%
XLV expense ratio

Pair scorecard

XLV costs 0.52 points a year less; their one-year returns differ by 22.3 points; XLV is far larger, $47.0bn against $1.2bn.

FTXH vs XLV: Differences, Returns & Fees
MeasureFTXHXLV
Return
Total return, 1 year+47.9%+25.6%
Benchmark
What it tracksNasdaq US Smart Pharmaceuticals IndexHealth Care Select Sector Index
Cost and size
Expense ratio0.60%0.08%
Net assets, as of Oct 27, 2026$1.2bn$47.0bn
Holdings
Holdings in common45%
Top ten holdings, share of the fund54.8%60.6%

Holdings in common uses holdings dated Oct 27, 2026. Method

Risk and return

Sep 30, 2016 to Oct 23, 2026 · 525 weekly returns
FTXH XLV
Return
Total return edge XLV +145.2% +193.9%
Annualized edge XLV +9.3% +11.3%
Price return edge XLV +116.4% +148.6%
Risk
Volatility edge XLV (slight) 18.3% 17.0%
Max drawdown edge XLV −28.9% −24.3%
Risk-adjusted
Sharpe edge XLV 0.44 0.57
Sortino edge XLV 0.63 0.82
Calmar edge XLV 0.32 0.46
Reading

XLV returned more: +193.9% to +145.2%. XLV swung slightly less: 17.0% to 18.3%. XLV fell less at its worst: −24.3% to −28.9%.

Full scorecard

9 measures, with how each is measured
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Risk and return: FTXH vs XLV: Differences, Returns & Fees
MeasureFTXHXLVEdgeHow it is measured
Return
Total return+145.2%+193.9%XLVPrice change plus distributions, reinvested.
Annualized+9.3%+11.3%XLVTotal return as a yearly rate.
Price return+116.4%+148.6%XLVPrice change alone, distributions left out.
Risk
Volatility18.3%17.0%XLV (slight)Spread of weekly returns, annualized. Lower is steadier.
Downside deviation12.8%11.8%XLV (slight)Like volatility, counting only weeks below the Treasury bill rate.
Max drawdown−28.9%−24.3%XLVDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.440.57XLVReturn above Treasury bills per unit of volatility.
Sortino0.630.82XLVReturn above Treasury bills per unit of downside deviation.
Calmar0.320.46XLVAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 525 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

45%

By the books each fund has filed, FTXH and XLV hold 45% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

45% in common

Positions both hold · largest shared weight first FTXH XLV
AbbVie Inc. 7.68% 7.78%
Eli Lilly and Company 7.62% 15.77%
Johnson & Johnson 6.95% 9.96%
Merck & Co., Inc. 6.60% 5.38%
Amgen Inc. 3.58% 3.72%
Gilead Sciences, Inc. 3.74% 3.03%
Pfizer Inc. 7.20% 2.61%
Vertex Pharmaceuticals Incorporated 3.29% 2.03%
Bristol-Myers Squibb Company 3.17% 1.93%
Regeneron Pharmaceuticals, Inc. 3.51% 1.23%
Moderna, Inc. 0.71% 1.19%
Illumina, Inc. 2.22% 0.65%
Only in one fund ↓
Only in FTXH
United Therapeutics Corporation 3.54%
Exelixis, Inc. 2.50%
Jazz Pharmaceuticals Plc 2.26%
Halozyme Therapeutics, Inc. 1.77%
Medpace Holdings, Inc. 1.60%
Neurocrine Biosciences, Inc. 1.19%
Alnylam Pharmaceuticals, Inc. 1.12%
Elanco Animal Health Incorporated 1.12%
Only in XLV
UNITEDHEALTH GROUP INC 5.66%
THERMO FISHER SCIENTIFIC INC 3.94%
ABBOTT LABORATORIES 2.74%
INTUITIVE SURGICAL INC 2.42%
DANAHER CORP 2.23%
CVS HEALTH CORP 1.79%
MEDTRONIC PLC 1.77%
MCKESSON CORP 1.73%
Check overlap with more funds →

Side by side

FTXH First Trust Nasdaq Pharmaceuticals ETF XLV State Street Health Care Select Sector SPDR ETF
Where it sits Stock ETF Stock ETF
What it is Tracks an index Tracks an index of Health care
Total return, 1 year +47.9% +25.6%
Expense ratio 0.60% 0.08%
Already in the S&P 500 68.0% 99.7%
Holdings 50 62
Net assets, as of Oct 27, 2026 $1.2bn $47.0bn

FTXH and XLV on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-5DDA0FE84E

FTXH and XLV are built for the same job. How do they differ in cost, holdings and results?

  1. What each follows. FTXH follows Nasdaq US Smart Pharmaceuticals Index and XLV follows Health Care Select Sector Index.
  2. Holdings in common. 45% of the weight is in the same securities (holdings dated Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 FTXH returned +47.9% and XLV +25.6% with distributions reinvested, a gap of 22.3 points.

Data as of Oct 28, 2026.

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About each fund
FTXH

FTXH tracks an index. Over the year to Oct 28, 2026 it returned +47.9% with distributions reinvested. The prospectus expense ratio is 0.60% a year. By its holdings published by its issuer for Oct 27, 2026, 68% of the fund by weight is stocks the S&P 500 also holds, across 50 positions, with the top ten at 54.8%.

XLV

XLV tracks an index of Health care. Over the year to Oct 28, 2026 it returned +25.6% with distributions reinvested. The prospectus expense ratio is 0.08% a year. By its holdings published by its issuer for Oct 27, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 62 positions, with the top ten at 60.6%.

Questions people ask

Which returned more over the last year, FTXH or XLV?
In the year to Oct 28, 2026, with distributions reinvested, FTXH returned +47.9% and XLV +25.6%.
Which is cheaper, FTXH or XLV?
XLV is cheaper, by 0.52 percentage points a year. That is about $52 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do FTXH and XLV overlap with the S&P 500?
By their latest filed holdings, 68% of FTXH and 100% of XLV by weight is stocks the S&P 500 already holds.
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ETFIQ, FTXH against XLV, data as of Oct 28, 2026. https://etfiq.com/compare/any/ftxh-vs-xlv

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