Data as of .
ANEW vs FMED: which is really different?
ANEW and FMED hold 10% of their weight in the same names, and FMED returned more over the year.
ETFIQ Off-Index Score: FMED scores higher
How much of it is not the index it is sold as an alternative to?
A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed
10% of the two portfolios are the same securities at the same weight.
What they hold in common
By the books each fund has filed, ANEW and FMED hold 10% of their money in the same securities at the same weight.
| Holding | ANEW | FMED |
|---|---|---|
| DANAHER CORP | 2.39% | 3.43% |
| EDWARDS LIFESCIENCES CORP | 1.87% | 2.12% |
| MODERNA INC | 1.87% | 2.11% |
| INTUITIVE SURGICAL INC | 1.68% | 2.93% |
| BOSTON SCIENTIFIC CORP | 1.44% | 1.44% |
| GUARDANT HEALTH INC | 0.78% | 1.39% |
| COGENT BIOSCIENCES INC | 0.24% | 2.86% |
| Only in ANEW | Only in FMED |
|---|---|
| DOORDASH INC - A 2.35% | UCB SA 4.75% |
| ABBVIE INC 2.33% | LIFESTANCE HEALTH GROUP INC 4.29% |
| DEERE & CO 2.31% | 10X GENOMICS INC 3.12% |
| MICROSOFT CORP 2.23% | ALNYLAM PHARMACEUTICALS INC 2.80% |
| ABBOTT LABORATORIES 2.18% | ARGENX SE 2.79% |
| SYMRISE AG 2.18% | LEGEND BIOTECH CORP 2.30% |
| INTL FLAVORS & FRAGRANCES 2.17% | UNITEDHEALTH GROUP INC 2.26% |
| APPLE INC 2.12% | BIO TECHNE CORP 2.25% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 18, 2026.
Performance, window by window
| Window | Total return | vs the S&P 500 | vs the Nasdaq-100 | |||
|---|---|---|---|---|---|---|
| ANEW | FMED | ANEW | FMED | ANEW | FMED | |
| 3 months | +6.5% | +21.3% | +4.2 pts | +19.0 pts | +8.9 pts | +23.7 pts |
| 6 months | +19.1% | +32.3% | +1.1 pts | +14.3 pts | −5.1 pts | +8.0 pts |
| 1 year | +3.9% | +28.3% | −12.7 pts | +11.7 pts | −17.9 pts | +6.5 pts |
| 3 years | +56.3% | +39.6% | −22.1 pts | −38.8 pts | −41.9 pts | −58.5 pts |
| Since launch | +40.4% | +25.8% | −97.4 pts | −57.6 pts | −118.3 pts | −78.1 pts |
| ANEW ProShares MSCI Transformational Changes ETF Holds 146 stocks in broad innovation and megatrends, 51% of its weight in S&P 500 companies | FMED Fidelity Disruptive Medicine ETF Holds 68 stocks in broad innovation and megatrends, 25% of its weight in S&P 500 companies | |
|---|---|---|
| Issuer | ProShares | Fidelity |
| Theme | Broad innovation and megatrends | Broad innovation and megatrends |
| In the S&P 500 | 51.0% | 25.4% |
| Active share vs the S&P 500 | 76.2% | 97.1% |
| In the Nasdaq-100 | 25.2% | 8.7% |
| Holdings | 146 | 68 |
| Top ten, share of the fund | 22.4% | 31.5% |
| Expense ratio | 0.45% | 0.50% |
| Fee for the differing part | 0.59% | 0.51% |
| Total return, 1 year | +3.9% | +28.3% |
| vs the S&P 500 | −12.7 pts | +11.7 pts |
| vs the Nasdaq-100 | −17.9 pts | +6.5 pts |
| Below its high | −2.0% | −3.8% |
| Net assets | $8m | $52m |
ANEW in plain words
By weight, 51% of ANEW's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 76%. The top ten holdings are 22% of the fund across 146 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +3.9% with distributions reinvested against +16.6% for the S&P 500, so a holder was behind by 12.7 pts.
FMED in plain words
By weight, 25% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 32% of the fund across 68 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +28.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 11.7 pts.
Questions people ask
- Do ANEW and FMED hold the same stocks?
- By their latest filings, 10% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
- Which is more different from the S&P 500, ANEW or FMED?
- ANEW has 51% of its weight in S&P 500 names and FMED has 25%, so FMED differs more from the index.
- Which is cheaper, ANEW or FMED?
- ANEW charges 0.45% a year and FMED charges 0.50%, so ANEW is cheaper. Fees come from each fund's prospectus.
Other comparisons
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, ANEW against FMED, data as of Sep 18, 2026. https://etfiq.com/compare/themes/anew-vs-fmed Free to use with attribution; the underlying files are at Open data.