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Data as of Sep 21, 2026.

ETFIQetfiq.com · independent ETF data

ETHA vs XBI: how they differ

ETHA and XBI hold 0% of their weight in the same names, and XBI returned more over the year.

iShares Ethereum Trust ETF and State Street SPDR S&P Biotech ETF.

What they hold in common

By the books each fund has filed, ETHA and XBI hold 0% of their money in the same securities at the same weight.

Only in each
Only in ETHAOnly in XBI
ETHER 100.00%TWIST BIOSCIENCE CORP 1.92%
USD CASH 0.00%MODERNA INC 1.64%
NATERA INC 1.61%
ABBVIE INC 1.51%
HALOZYME THERAPEUTICS INC 1.51%
TG THERAPEUTICS INC 1.50%
CRISPR THERAPEUTICS AG 1.50%
ORUKA THERAPEUTICS INC 1.49%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026.

ETHA and XBI on the fields both publish, as of Sep 21, 2026. Source: ETFIQ.
ETHA
iShares Ethereum Trust ETF
XBI
State Street SPDR S&P Biotech ETF
Where it sitsCore fundCore fund
IssueriSharesState Street
What it isHolds etherTracks the S&P Biotech
Total return, 1 year−42.6%+62.8%
S&P 500 over the same days+16.6%+16.6%
Gap to the S&P 500−59.2 pts+46.3 pts
Expense ratio0.25%0.35%
Holdings2167
Net assets$9.2bn$10.3bn

ETHA in plain words

ETHA holds ether. Over the year to Sep 18, 2026 it returned −42.6% with distributions reinvested, against +16.6% for the S&P 500 and +21.8% for the Nasdaq-100. The prospectus expense ratio is 0.25% a year. It sat 45.6% below its high of Aug 22, 2025 on Sep 18, 2026.

XBI in plain words

XBI tracks the S&P Biotech. Over the year to Sep 18, 2026 it returned +62.8% with distributions reinvested, against +16.6% for the S&P 500 and +21.8% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings published by its issuer for Sep 18, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 167 positions, with the top ten at 15.6%. It sat 9.3% below its high of Feb 8, 2021 on Sep 18, 2026.

Questions people ask

Which returned more over the last year, ETHA or XBI?
In the year to Sep 21, 2026, with distributions reinvested, ETHA returned −42.6% and XBI returned +62.8%, so XBI returned more.
Which is cheaper, ETHA or XBI?
ETHA charges 0.25% a year and XBI charges 0.35%, so ETHA is cheaper. Fees come from each fund's prospectus.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

ETHA against XBI, ETFIQ, data as of Sep 21, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, ETHA against XBI, data as of Sep 21, 2026. https://etfiq.com/compare/any/etha-vs-xbi Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources