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LFSC · F/m Emerald Life Sciences Innovation ETF

LFSC holds 39 stocks. 100% of it is not in the S&P 500, and its top ten are 55% of the fund.

not published · Themes desk · data as of

0.0%Already in the S&P 500
100.0%Active share vs the S&P 500
54.7%Top ten holdings
+61.7%Total return, 1 year

Its ten largest positions

LFSC top ten, 54.7% of the fund, from the holdings filed for May 31, 2026. Source: the fund’s SEC filing.
HoldingTickerWeight
Travere Therapeutics IncTVTX7.66%
Cogent Biosciences IncCOGT7.52%
LivaNova PLCLIVN7.11%
Spyre Therapeutics IncSYRE6.40%
Guardant Health IncGH5.52%
Mirum Pharmaceuticals IncMIRM4.92%
Corcept Therapeutics IncCORT4.79%
United Therapeutics CorpUTHR4.15%
VeraDermics IncMANE3.41%
Savara IncSVRA3.22%

Period by period

LFSC over each window to Sep 4, 2026. Every figure is an ETFIQ calculation. Source: ETFIQ.
WindowTotal returnS&P 500Gap to S&P 500Gap to Nasdaq-100
3 months+21.8%+4.7%+17.1 pts+19.7 pts
6 months+33.6%+15.2%+18.5 pts+13.5 pts
1 year+61.7%+20.0%+41.7 pts+36.1 pts
Since launch+85.3%+38.2%+47.1 pts+35.4 pts

In plain words

The top ten holdings are 55% of the fund across 39 positions, as filed for May 31, 2026. Over the year to Sep 4, 2026 the fund returned +61.7% with distributions reinvested against +20.0% for the S&P 500, so a holder was ahead by 41.7 pts.

LFSC (F/m Emerald Life Sciences Innovation ETF), themes desk fields as of Sep 4, 2026. Source: ETFIQ.
Theme (ETFIQ, editorial)Broad innovation and megatrends
LaunchedOct 31, 2024
Already in the S&P 500, by weight (ETFIQ)0.0%
Active share vs the S&P 500 (ETFIQ)100.0%
Already in the Nasdaq-100, by weight (ETFIQ)0.6%
Active share vs the Nasdaq-100 (ETFIQ)99.9%
Top ten holdings weight54.7%
Holdings39
Holdings as of (SEC N-PORT)May 31, 2026
Top holdingsTravere Therapeutics Inc 7.7%, Cogent Biosciences Inc 7.5%, LivaNova PLC 7.1%, Spyre Therapeutics Inc 6.4%, Guardant Health Inc 5.5%, Mirum Pharmaceuticals Inc 4.9%, Corcept Therapeutics Inc 4.8%, United Therapeutics Corp 4.2%, VeraDermics Inc 3.4%, Savara Inc 3.2%
Net assets (SEC filing, whole fund, as filed for May 31, 2026)$105m
Below its all-time high (ETFIQ)−4.8%
Expense ratio (prospectus XBRL)0.54%
Fee for the part that differs from the S&P 500, active expense ratio (ETFIQ)0.54%
Closest funds by holdings overlapHELX 16%, EKG 12%, FMED 11%, GNOM 10%

Holdings from the fund’s latest public SEC N-PORT filing; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. How this desk computes every figure

Questions people ask

How much of LFSC is already in the S&P 500?
By its holdings filed for May 31, 2026, 0% of LFSC by weight is stocks the S&P 500 already holds. Its active share against the index is 100%, so that share is the part doing something different.
What does LFSC hold?
39 positions as filed for May 31, 2026, with the top ten at 55% of the fund. The largest are Travere Therapeutics Inc at 7.7%, Cogent Biosciences Inc at 7.5%, LivaNova PLC at 7.1%.
Has LFSC beaten the S&P 500?
Over the year to Sep 4, 2026 LFSC returned +61.7% with distributions reinvested, against +20.0% for the S&P 500, so it finished ahead of the index by 41.7 points.
What does LFSC cost?
The prospectus expense ratio is 0.54% a year. Because 100% of the fund differs from the S&P 500, the fee on that differing part works out at 0.54%.

The words on this page

Active share
The part of the fund doing something the index is not, as a percentage. It is the part a fee is actually buying.
Weight overlap
The share of money two portfolios hold in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice.
Already in the index
The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at very different weights.
Top ten
What the ten largest positions add up to. The higher it is, the more the fund is a bet on a few companies rather than a theme.

Every term this desk uses, defined in full on the themes desk vocabulary page.

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

Funds near this one

Put this on your own page

The difference bar for LFSC, redrawn every trading night. Free to use with the credit link; paste these two lines into any page or newsletter.

LFSC difference bar, ETFIQ

<a href="https://etfiq.com/funds/LFSC.html"><img src="https://etfiq.com/embed/themes/LFSC.svg" alt="LFSC difference bar, ETFIQ" width="640"></a>
<p><a href="https://etfiq.com/funds/LFSC.html">LFSC difference bar, updated daily by ETFIQ</a></p>
LFSC on the themes desk, ETFIQ, data as of Sep 4, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. ETFIQ is an independent publisher, is not a fund issuer, broker-dealer or investment adviser, and makes no recommendations.
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Open LFSC on the live ETFIQ desk, where the figures update as the desk refreshes.

Cite this page. ETFIQ, LFSC on the themes desk, data as of Sep 4, 2026. https://etfiq.com/funds/LFSC.html Free to use with attribution; the underlying files are at Open data.

How this desk computes every figure · Standards and sources