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EKG · First Trust Nasdaq Lux Digital Health Solutions ETF

EKG holds 39 stocks. 100% of it is not in the S&P 500, and its top ten are 62% of the fund.

First Trust · Themes desk · data as of

43.1%Already in the S&P 500
99.6%Active share vs the S&P 500
61.8%Top ten holdings
+25.7%Total return, 1 year

Its ten largest positions

EKG top ten, 61.8% of the fund, from the holdings filed for Sep 3, 2026. Source: the fund’s SEC filing.
HoldingTickerWeight
Veeva Systems Inc. (Class A)VEEV10.10%
IQVIA Holdings Inc.IQV9.82%
DexCom, Inc.DXCM7.90%
ResMed Inc.RMD5.78%
Guardant Health, Inc.GH5.55%
Illumina, Inc.ILMN5.33%
Natera, Inc.NTRA5.09%
Intuitive Surgical, Inc.ISRG4.75%
Oscar Health, Inc. (Class A)OSCR3.94%
Tempus AI, Inc. (Class A)TEM3.49%

Period by period

EKG over each window to Sep 4, 2026. Every figure is an ETFIQ calculation. Source: ETFIQ.
WindowTotal returnS&P 500Gap to S&P 500Gap to Nasdaq-100
3 months+26.6%+4.7%+21.9 pts+24.5 pts
6 months+26.9%+15.2%+11.8 pts+6.8 pts
1 year+25.7%+20.0%+5.8 pts+0.1 pts
3 years+37.3%+78.0%−40.6 pts−56.2 pts
Since launch+10.5%+83.9%−73.4 pts−99.3 pts

In plain words

The top ten holdings are 62% of the fund across 39 positions, as filed for Sep 3, 2026. Over the year to Sep 4, 2026 the fund returned +25.7% with distributions reinvested against +20.0% for the S&P 500, so a holder was ahead by 5.8 pts.

EKG (First Trust Nasdaq Lux Digital Health Solutions ETF), themes desk fields as of Sep 4, 2026. Source: ETFIQ.
Theme (ETFIQ, editorial)Healthcare innovation and GLP-1
LaunchedMar 23, 2022
Already in the S&P 500, by weight (ETFIQ)43.1%
Active share vs the S&P 500 (ETFIQ)99.6%
Already in the Nasdaq-100, by weight (ETFIQ)12.7%
Active share vs the Nasdaq-100 (ETFIQ)99.2%
Top ten holdings weight61.8%
Holdings39
Holdings as of (SEC N-PORT)Sep 3, 2026
Top holdingsVeeva Systems Inc. (Class A) 10.1%, IQVIA Holdings Inc. 9.8%, DexCom, Inc. 7.9%, ResMed Inc. 5.8%, Guardant Health, Inc. 5.5%, Illumina, Inc. 5.3%, Natera, Inc. 5.1%, Intuitive Surgical, Inc. 4.8%, Oscar Health, Inc. (Class A) 3.9%, Tempus AI, Inc. (Class A) 3.5%
Net assets (SEC filing, whole fund, as filed for Sep 3, 2026)$3m
Below its all-time high (ETFIQ)−2.3%
Expense ratio (prospectus XBRL)0.65%
Fee for the part that differs from the S&P 500, active expense ratio (ETFIQ)0.65%
Closest funds by holdings overlapHEAL 46%, GNOM 25%, HTEC 24%, ARKG 24%, FMED 22%

Holdings from the fund’s latest public SEC N-PORT filing; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. How this desk computes every figure

Questions people ask

How much of EKG is already in the S&P 500?
By its holdings filed for Sep 3, 2026, 43% of EKG by weight is stocks the S&P 500 already holds. Its active share against the index is 100%, so that share is the part doing something different.
What does EKG hold?
39 positions as filed for Sep 3, 2026, with the top ten at 62% of the fund. The largest are Veeva Systems Inc. (Class A) at 10.1%, IQVIA Holdings Inc. at 9.8%, DexCom, Inc. at 7.9%.
Has EKG beaten the S&P 500?
Over the year to Sep 4, 2026 EKG returned +25.7% with distributions reinvested, against +20.0% for the S&P 500, so it finished ahead of the index by 5.8 points.
What does EKG cost?
The prospectus expense ratio is 0.65% a year. Because 100% of the fund differs from the S&P 500, the fee on that differing part works out at 0.65%.

The words on this page

Active share
The part of the fund doing something the index is not, as a percentage. It is the part a fee is actually buying.
Weight overlap
The share of money two portfolios hold in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice.
Already in the index
The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at very different weights.
Top ten
What the ten largest positions add up to. The higher it is, the more the fund is a bet on a few companies rather than a theme.

Every term this desk uses, defined in full on the themes desk vocabulary page.

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

Funds near this one

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EKG difference bar, ETFIQ

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<p><a href="https://etfiq.com/funds/EKG.html">EKG difference bar, updated daily by ETFIQ</a></p>
EKG on the themes desk, ETFIQ, data as of Sep 4, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. ETFIQ is an independent publisher, is not a fund issuer, broker-dealer or investment adviser, and makes no recommendations.
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Cite this page. ETFIQ, EKG on the themes desk, data as of Sep 4, 2026. https://etfiq.com/funds/EKG.html Free to use with attribution; the underlying files are at Open data.

How this desk computes every figure · Standards and sources