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MSGR Direxion mRNA ETF

Tracks therapeutics and medical devices

MSGR has not filed its holdings yet, so there is nothing to look through.

Direxion · Thematic ETFs · data as of

Key facts

not filedAlready in the S&P 500
not filedActive share vs the S&P 500
not publishedTop ten holdings
0.0%Total return, 1 year

Method

8th of 9 therapeutics and medical devices ETFs by net assets

Its price barely moved. MSGR closed unchanged on 89 of its 90 trading days. A price that does not move is a price nobody traded at, so the figures above describe the days somebody did trade rather than what the fund did, and ETFIQ does not rank it against funds that trade every day. That is why it carries no Off-Index Score score: a fund outside the set has no score rather than a low one.

Method

Period by period

MSGR over each window to Sep 11, 2026. Every figure is an ETFIQ calculation. Source: ETFIQ.
WindowTotal returnS&P 500Gap to S&P 500Gap to Nasdaq-100
3 months0.0%+3.3%−3.3 pts+0.8 pts
6 months0.0%+16.0%−16.0 pts−20.7 pts
1 year0.0%+17.5%−17.5 pts−23.0 pts
Since launch0.0%+21.3%−21.3 pts−26.4 pts

Method

In plain words

Over the year to Sep 11, 2026 the fund returned 0.0% with distributions reinvested against +17.5% for the S&P 500, so a holder was behind by 17.5 pts.

MSGR (Direxion mRNA ETF), thematic ETFs fields as of Sep 11, 2026. Source: ETFIQ.
Theme (ETFIQ, editorial)Therapeutics and medical devices
LaunchedJul 28, 2025
Below its all-time high (ETFIQ)0.0%

Holdings from the fund’s latest public SEC N-PORT filing; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. How these figures are computed

Questions people ask

Has MSGR beaten the S&P 500?
Over the year to Sep 11, 2026 MSGR returned 0.0% with distributions reinvested, against +17.5% for the S&P 500, so it finished behind the index by 17.5 points.

The words on this page

Active share
The part of the fund doing something the index is not, as a percentage. It is the part a fee is actually buying.
Weight overlap
The share of money two portfolios hold in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice.
Already in the index
The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at very different weights.
Top ten
What the ten largest positions add up to. The higher it is, the more the fund is a bet on a few companies rather than a theme.

Every term used here, defined in full on the thematic ETFs vocabulary page.

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

Funds near this one

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MSGR difference bar, ETFIQ

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<p><a href="https://etfiq.com/funds/MSGR">MSGR difference bar, updated daily by ETFIQ</a></p>

Where MSGR is written about

MSGR, Thematic ETFs, ETFIQ, data as of Sep 11, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. ETFIQ is an independent publisher, is not a fund issuer, broker-dealer or investment adviser, and makes no recommendations.
Use this data, or open the live card

Open MSGR live on ETFIQ, where the figures refresh with the data.

Cite this page. ETFIQ, MSGR, thematic ETFs, data as of Sep 11, 2026. https://etfiq.com/funds/MSGR Free to use with attribution; the underlying files are at Open data.

How these figures are computed · Standards and sources