Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
VBK vs XBI: how they differ
VBK and XBI hold 10% of their weight in the same names, and XBI returned more over the year.
Vanguard Small-Cap Growth Index Fund and State Street(R) SPDR(R) S&P(R) Biotech ETF.
What they hold in common
By the books each fund has filed, VBK and XBI hold 10% of their money in the same securities at the same weight.
| Holding | VBK | XBI |
|---|---|---|
| REVOLUTION Medicines Inc | 1.07% | 1.21% |
| Natera Inc | 1.04% | 1.17% |
| Incyte Corp | 0.54% | 1.00% |
| Neurocrine Biosciences Inc | 0.48% | 0.97% |
| Bridgebio Pharma Inc | 0.37% | 1.03% |
| Exelixis Inc | 0.37% | 0.96% |
| Ionis Pharmaceuticals Inc | 0.35% | 1.00% |
| Cytokinetics Inc | 0.33% | 1.18% |
| Insmed Inc | 0.33% | 1.08% |
| United Therapeutics Corp | 0.32% | 0.93% |
| BioMarin Pharmaceutical Inc | 0.31% | 0.95% |
| Arrowhead Pharmaceuticals Inc | 0.31% | 1.07% |
| Only in VBK | Only in XBI |
|---|---|
| Credo Technology Group Holding Ltd 1.27% | Apogee Therapeutics Inc 1.49% |
| Astera Labs Inc 1.05% | Moderna Inc 1.41% |
| Twilio Inc 0.88% | Oruka Therapeutics Inc 1.38% |
| Casey's General Stores Inc 0.83% | Praxis Precision Medicines Inc 1.29% |
| Carpenter Technology Corp 0.82% | Erasca Inc 1.27% |
| Curtiss-Wright Corp 0.79% | SELLAS Life Sciences Group Inc 1.19% |
| FTAI Aviation Ltd 0.78% | Dianthus Therapeutics Inc 1.19% |
| nVent Electric PLC 0.77% | Scholar Rock Holding Corp 1.16% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026.
| VBK Vanguard Small-Cap Growth Index Fund | XBI State Street(R) SPDR(R) S&P(R) Biotech ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | Vanguard | State Street |
| What it is | Small-Cap Growth | SPDR S&P Biotech |
| Total return, 1 year | +13.8% | +64.0% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | −3.7 pts | +46.5 pts |
| Expense ratio | 0.05% | 0.35% |
| Already in the S&P 500 | 10.2% | 8.5% |
| Holdings | 545 | 150 |
VBK in plain words
VBK is an index equity fund tracking the Small-Cap Growth. Over the year to Sep 11, 2026 it returned +13.8% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.05% a year. By its holdings filed for Jun 30, 2026, 10% of the fund by weight is stocks the S&P 500 also holds, across 545 positions, with the top ten at 9.3%. It sat 7.0% below its high of Aug 17, 2026 on Sep 11, 2026.
XBI in plain words
XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Jun 30, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 150 positions, with the top ten at 13.3%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, VBK or XBI?
- In the year to Sep 12, 2026, with distributions reinvested, VBK returned +13.8% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, VBK or XBI?
- VBK charges 0.05% a year and XBI charges 0.35%, so VBK is cheaper. Fees come from each fund's prospectus.
- How much do VBK and XBI overlap with the S&P 500?
- By their latest filed holdings, 10% of VBK and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 10% of their books are the same securities at the same weight.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, VBK against XBI, data as of Sep 12, 2026. https://etfiq.com/compare/any/VBK-XBI Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources