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Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.

ETFIQetfiq.com · independent ETF data

USFR vs XBI: how they differ

USFR and XBI hold 0% of their weight in the same names, and XBI returned more over the year.

WisdomTree Floating Rate Treasury Fund and State Street(R) SPDR(R) S&P(R) Biotech ETF.

What they hold in common

By the books each fund has filed, USFR and XBI hold 0% of their money in the same securities at the same weight.

Largest positions each one holds and the other does not
Only in USFROnly in XBI
UNITED STATES OF AMERICA - BUREAU OF THE 28.04%Apogee Therapeutics Inc 1.49%
UNITED STATES OF AMERICA - BUREAU OF THE 28.01%Moderna Inc 1.41%
UNITED STATES OF AMERICA - BUREAU OF THE 28.00%Twist Bioscience Corp 1.41%
UNITED STATES OF AMERICA - BUREAU OF THE 15.95%Oruka Therapeutics Inc 1.38%
Kymera Therapeutics Inc 1.36%
Viking Therapeutics Inc 1.31%
Praxis Precision Medicines Inc 1.29%
Erasca Inc 1.27%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and May 31, 2026.

USFR and XBI on the fields both publish, as of Sep 12, 2026. Source: ETFIQ.
USFR
WisdomTree Floating Rate Treasury Fund
XBI
State Street(R) SPDR(R) S&P(R) Biotech ETF
Where it sitsCore index fundCore index fund
IssuerWisdomTreeState Street
What it isFloating Rate TreasurySPDR S&P Biotech
Total return, 1 year+4.1%+64.0%
S&P 500 over the same days+17.5%+17.5%
Gap to the S&P 500−13.4 pts+46.5 pts
Expense ratio0.15%0.35%
Holdings4150

USFR in plain words

USFR is a bond fund tracking the Floating Rate Treasury. Over the year to Sep 11, 2026 it returned +4.1% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.15% a year.

XBI in plain words

XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Jun 30, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 150 positions, with the top ten at 13.3%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.

Questions people ask

Which returned more over the last year, USFR or XBI?
In the year to Sep 12, 2026, with distributions reinvested, USFR returned +4.1% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
Which is cheaper, USFR or XBI?
USFR charges 0.15% a year and XBI charges 0.35%, so USFR is cheaper. Fees come from each fund's prospectus.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

USFR against XBI, ETFIQ, data as of Sep 12, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, USFR against XBI, data as of Sep 12, 2026. https://etfiq.com/compare/any/USFR-XBI Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources