Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
USFR vs XBI: how they differ
USFR and XBI hold 0% of their weight in the same names, and XBI returned more over the year.
WisdomTree Floating Rate Treasury Fund and State Street(R) SPDR(R) S&P(R) Biotech ETF.
What they hold in common
By the books each fund has filed, USFR and XBI hold 0% of their money in the same securities at the same weight.
| Only in USFR | Only in XBI |
|---|---|
| UNITED STATES OF AMERICA - BUREAU OF THE 28.04% | Apogee Therapeutics Inc 1.49% |
| UNITED STATES OF AMERICA - BUREAU OF THE 28.01% | Moderna Inc 1.41% |
| UNITED STATES OF AMERICA - BUREAU OF THE 28.00% | Twist Bioscience Corp 1.41% |
| UNITED STATES OF AMERICA - BUREAU OF THE 15.95% | Oruka Therapeutics Inc 1.38% |
| Kymera Therapeutics Inc 1.36% | |
| Viking Therapeutics Inc 1.31% | |
| Praxis Precision Medicines Inc 1.29% | |
| Erasca Inc 1.27% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and May 31, 2026.
| USFR WisdomTree Floating Rate Treasury Fund | XBI State Street(R) SPDR(R) S&P(R) Biotech ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | WisdomTree | State Street |
| What it is | Floating Rate Treasury | SPDR S&P Biotech |
| Total return, 1 year | +4.1% | +64.0% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | −13.4 pts | +46.5 pts |
| Expense ratio | 0.15% | 0.35% |
| Holdings | 4 | 150 |
USFR in plain words
USFR is a bond fund tracking the Floating Rate Treasury. Over the year to Sep 11, 2026 it returned +4.1% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.15% a year.
XBI in plain words
XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Jun 30, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 150 positions, with the top ten at 13.3%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, USFR or XBI?
- In the year to Sep 12, 2026, with distributions reinvested, USFR returned +4.1% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, USFR or XBI?
- USFR charges 0.15% a year and XBI charges 0.35%, so USFR is cheaper. Fees come from each fund's prospectus.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, USFR against XBI, data as of Sep 12, 2026. https://etfiq.com/compare/any/USFR-XBI Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources