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Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.

ETFIQetfiq.com · independent ETF data

KRE vs XBI: how they differ

KRE and XBI hold 0% of their weight in the same names, and XBI returned more over the year.

State Street(R) SPDR(R) S&P(R) Regional Banking ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.

What they hold in common

By the books each fund has filed, KRE and XBI hold 0% of their money in the same securities at the same weight.

Largest positions each one holds and the other does not
Only in KREOnly in XBI
Pinnacle Financial Partners Inc 1.37%Apogee Therapeutics Inc 1.49%
Atlantic Union Bankshares Corp 1.37%Moderna Inc 1.41%
UMB Financial Corp 1.37%Twist Bioscience Corp 1.41%
Citizens Financial Group Inc 1.37%Oruka Therapeutics Inc 1.38%
Glacier Bancorp Inc 1.36%Kymera Therapeutics Inc 1.36%
Associated Banc-Corp 1.36%Viking Therapeutics Inc 1.31%
Cullen/Frost Bankers Inc 1.35%Praxis Precision Medicines Inc 1.29%
First Interstate BancSystem Inc 1.35%Erasca Inc 1.27%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026.

KRE and XBI on the fields both publish, as of Sep 12, 2026. Source: ETFIQ.
KRE
State Street(R) SPDR(R) S&P(R) Regional Banking ETF
XBI
State Street(R) SPDR(R) S&P(R) Biotech ETF
Where it sitsCore index fundCore index fund
IssuerState StreetState Street
What it isSPDR S&P Regional BankingSPDR S&P Biotech
Total return, 1 year+16.1%+64.0%
S&P 500 over the same days+17.5%+17.5%
Gap to the S&P 500−1.4 pts+46.5 pts
Expense ratio0.35%0.35%
Already in the S&P 5006.7%8.5%
Holdings161150

KRE in plain words

KRE is an index equity fund tracking the SPDR S&P Regional Banking. Over the year to Sep 11, 2026 it returned +16.1% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Jun 30, 2026, 7% of the fund by weight is stocks the S&P 500 also holds, across 161 positions, with the top ten at 13.6%. It sat 5.2% below its high of Aug 14, 2026 on Sep 11, 2026.

XBI in plain words

XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. By its holdings filed for Jun 30, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 150 positions, with the top ten at 13.3%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.

Questions people ask

Which returned more over the last year, KRE or XBI?
In the year to Sep 12, 2026, with distributions reinvested, KRE returned +16.1% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
Which is cheaper, KRE or XBI?
KRE charges 0.35% a year and XBI charges 0.35%, so KRE is cheaper. Fees come from each fund's prospectus.
How much do KRE and XBI overlap with the S&P 500?
By their latest filed holdings, 7% of KRE and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

KRE against XBI, ETFIQ, data as of Sep 12, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, KRE against XBI, data as of Sep 12, 2026. https://etfiq.com/compare/any/KRE-XBI Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources