Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
IBB vs VPL: how they differ
IBB and VPL hold 0% of their weight in the same names, and IBB returned more over the year.
iShares Biotechnology ETF and Vanguard Pacific Stock Index Fund.
What they hold in common
By the books each fund has filed, IBB and VPL hold 0% of their money in the same securities at the same weight.
| Only in IBB | Only in VPL |
|---|---|
| Vertex Pharmaceuticals, Inc. 8.09% | Samsung Electronics Co Ltd 6.06% |
| Amgen, Inc. 7.84% | SK hynix Inc 4.12% |
| Gilead Sciences, Inc. 6.85% | Commonwealth Bank of Australia 1.80% |
| Regeneron Pharmaceuticals, Inc. 4.91% | Toyota Motor Corp 1.74% |
| Argenx SE 3.76% | Mitsubishi UFJ Financial Group Inc 1.69% |
| Alnylam Pharmaceuticals, Inc. 3.12% | BHP Group Ltd 1.66% |
| Natera, Inc. 2.89% | Hitachi Ltd 1.18% |
| Revolution Medicines, Inc. 2.78% | Advantest Corp 1.16% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Apr 30, 2026 and Jun 30, 2026.
| IBB iShares Biotechnology ETF | VPL Vanguard Pacific Stock Index Fund | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | iShares | Vanguard |
| What it is | Biotechnology | Pacific Stock |
| Total return, 1 year | +41.5% | +36.9% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | +24.0 pts | +19.4 pts |
| Expense ratio | 0.44% | 0.07% |
| Already in the S&P 500 | 35.6% | 0.1% |
| Holdings | 248 | 2335 |
IBB in plain words
IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Jun 30, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 248 positions, with the top ten at 44.8%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.
VPL in plain words
VPL is an index equity fund tracking the Pacific Stock. Over the year to Sep 11, 2026 it returned +36.9% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.07% a year. By its holdings filed for Apr 30, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 2335 positions, with the top ten at 21.6%.
Questions people ask
- Which returned more over the last year, IBB or VPL?
- In the year to Sep 12, 2026, with distributions reinvested, IBB returned +41.5% and VPL returned +36.9%, so IBB returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, IBB or VPL?
- IBB charges 0.44% a year and VPL charges 0.07%, so VPL is cheaper. Fees come from each fund's prospectus.
- How much do IBB and VPL overlap with the S&P 500?
- By their latest filed holdings, 36% of IBB and 0% of VPL by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBB against VPL, data as of Sep 12, 2026. https://etfiq.com/compare/any/IBB-VPL Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources