Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
IBB vs IXUS: how they differ
IBB and IXUS hold 0% of their weight in the same names, and IBB returned more over the year.
iShares Biotechnology ETF and iShares Core MSCI Total International Stock ETF.
What they hold in common
By the books each fund has filed, IBB and IXUS hold 0% of their money in the same securities at the same weight.
| Holding | IBB | IXUS |
|---|---|---|
| Legend Biotech Corp. | 0.34% | 0.01% |
| Only in IBB | Only in IXUS |
|---|---|
| Vertex Pharmaceuticals, Inc. 8.09% | Taiwan Semiconductor Manufacturing Compa 4.04% |
| Amgen, Inc. 7.84% | ASML Holding N.V. 1.32% |
| Gilead Sciences, Inc. 6.85% | SK hynix Inc. 1.15% |
| Regeneron Pharmaceuticals, Inc. 4.91% | Tencent Holdings Limited 0.91% |
| Argenx SE 3.76% | HSBC HOLDINGS PLC 0.75% |
| Alnylam Pharmaceuticals, Inc. 3.12% | ASTRAZENECA PLC 0.69% |
| Natera, Inc. 2.89% | Alibaba Group Holding Limited 0.67% |
| Revolution Medicines, Inc. 2.78% | Novartis AG 0.66% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Apr 30, 2026 and Jun 30, 2026.
| IBB iShares Biotechnology ETF | IXUS iShares Core MSCI Total International Stock ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | iShares | iShares |
| What it is | Biotechnology | Core MSCI Total International Stock |
| Total return, 1 year | +41.5% | +22.2% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | +24.0 pts | +4.7 pts |
| Expense ratio | 0.44% | 0.07% |
| Already in the S&P 500 | 35.6% | 0.0% |
| Holdings | 248 | 4185 |
IBB in plain words
IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Jun 30, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 248 positions, with the top ten at 44.8%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.
IXUS in plain words
IXUS is an index equity fund tracking the Core MSCI Total International Stock. Over the year to Sep 11, 2026 it returned +22.2% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.07% a year. By its holdings filed for Apr 30, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 4185 positions, with the top ten at 12.6%.
Questions people ask
- Which returned more over the last year, IBB or IXUS?
- In the year to Sep 12, 2026, with distributions reinvested, IBB returned +41.5% and IXUS returned +22.2%, so IBB returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, IBB or IXUS?
- IBB charges 0.44% a year and IXUS charges 0.07%, so IXUS is cheaper. Fees come from each fund's prospectus.
- How much do IBB and IXUS overlap with the S&P 500?
- By their latest filed holdings, 36% of IBB and 0% of IXUS by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBB against IXUS, data as of Sep 12, 2026. https://etfiq.com/compare/any/IBB-IXUS Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources