IDNA · iShares Genomics Immunology and Healthcare ETF
IDNA holds 60 stocks. 99% of it is not in the S&P 500, and its top ten are 48% of the fund.
Its ten largest positions
| Holding | Ticker | Weight | |
|---|---|---|---|
| REVOLUTION MEDICINES, INC. | 6.91% | ||
| MODERNA, INC. | 6.33% | ||
| IPSEN SA | 5.28% | ||
| Bayer Aktiengesellschaft | 4.41% | ||
| Takeda Pharmaceutical Company Limited | 4.25% | ||
| MERCK & CO., INC. | 4.18% | ||
| GSK PLC | 4.15% | ||
| BioNTech SE | 4.10% | ||
| Roche Holding AG | 4.02% | ||
| EXELIXIS, INC. | 3.82% |
Period by period
| Window | Total return | S&P 500 | Gap to S&P 500 | Gap to Nasdaq-100 |
|---|---|---|---|---|
| 3 months | +37.0% | +4.7% | +32.4 pts | +35.0 pts |
| 6 months | +35.0% | +15.2% | +19.9 pts | +14.8 pts |
| 1 year | +78.0% | +20.0% | +58.0 pts | +52.4 pts |
| 3 years | +82.9% | +78.0% | +4.9 pts | −10.6 pts |
| Since launch | +69.5% | +196.2% | −126.7 pts | −240.8 pts |
In plain words
The top ten holdings are 48% of the fund across 60 positions, as filed for Apr 30, 2026. Over the year to Sep 4, 2026 the fund returned +78.0% with distributions reinvested against +20.0% for the S&P 500, so a holder was ahead by 58.0 pts. It sits 24.8% below its all-time high of Sep 2, 2021.
| Theme (ETFIQ, editorial) | Genomics and biotech innovation |
|---|---|
| Launched | Jun 13, 2019 |
| Already in the S&P 500, by weight (ETFIQ) | 21.4% |
| Active share vs the S&P 500 (ETFIQ) | 99.1% |
| Already in the Nasdaq-100, by weight (ETFIQ) | 7.3% |
| Active share vs the Nasdaq-100 (ETFIQ) | 99.2% |
| Top ten holdings weight | 47.5% |
| Holdings | 60 |
| Holdings as of (SEC N-PORT) | Apr 30, 2026 |
| Top holdings | REVOLUTION MEDICINES, INC. 6.9%, MODERNA, INC. 6.3%, IPSEN SA 5.3%, Bayer Aktiengesellschaft 4.4%, Takeda Pharmaceutical Company Limited 4.2%, MERCK & CO., INC. 4.2%, GSK PLC 4.2%, BioNTech SE 4.1%, Roche Holding AG 4.0%, EXELIXIS, INC. 3.8% |
| Net assets (SEC filing, whole fund, as filed for Apr 30, 2026) | $160m |
| Below its all-time high (ETFIQ) | −24.8% |
| Expense ratio (prospectus XBRL) | 0.47% |
| Fee for the part that differs from the S&P 500, active expense ratio (ETFIQ) | 0.47% |
| Closest funds by holdings overlap | GNOM 20%, AGNG 12%, HTEC 11%, HELX 10% |
Holdings from the fund’s latest public SEC N-PORT filing; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. How this desk computes every figure
Questions people ask
- How much of IDNA is already in the S&P 500?
- By its holdings filed for Apr 30, 2026, 21% of IDNA by weight is stocks the S&P 500 already holds. Its active share against the index is 99%, so that share is the part doing something different.
- What does IDNA hold?
- 60 positions as filed for Apr 30, 2026, with the top ten at 48% of the fund. The largest are REVOLUTION MEDICINES, INC. at 6.9%, MODERNA, INC. at 6.3%, IPSEN SA at 5.3%.
- Has IDNA beaten the S&P 500?
- Over the year to Sep 4, 2026 IDNA returned +78.0% with distributions reinvested, against +20.0% for the S&P 500, so it finished ahead of the index by 58.0 points.
- What does IDNA cost?
- The prospectus expense ratio is 0.47% a year. Because 99% of the fund differs from the S&P 500, the fee on that differing part works out at 0.47%.
The words on this page
- Active share
- The part of the fund doing something the index is not, as a percentage. It is the part a fee is actually buying.
- Weight overlap
- The share of money two portfolios hold in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice.
- Already in the index
- The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at very different weights.
- Top ten
- What the ten largest positions add up to. The higher it is, the more the fund is a bet on a few companies rather than a theme.
Every term this desk uses, defined in full on the themes desk vocabulary page.
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Funds near this one
Put this on your own page
The difference bar for IDNA, redrawn every trading night. Free to use with the credit link; paste these two lines into any page or newsletter.
<a href="https://etfiq.com/funds/IDNA.html"><img src="https://etfiq.com/embed/themes/IDNA.svg" alt="IDNA difference bar, ETFIQ" width="640"></a>
<p><a href="https://etfiq.com/funds/IDNA.html">IDNA difference bar, updated daily by ETFIQ</a></p>Use this data, or open the live card
Open IDNA on the live ETFIQ desk, where the figures update as the desk refreshes.
Cite this page. ETFIQ, IDNA on the themes desk, data as of Sep 4, 2026. https://etfiq.com/funds/IDNA.html Free to use with attribution; the underlying files are at Open data.