Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
VNQ vs XBI: how they differ
VNQ and XBI hold 0% of their weight in the same names, and XBI returned more over the year.
Vanguard Real Estate Index Fund and State Street(R) SPDR(R) S&P(R) Biotech ETF.
What they hold in common
By the books each fund has filed, VNQ and XBI hold 0% of their money in the same securities at the same weight.
| Only in VNQ | Only in XBI |
|---|---|
| Vanguard Real Estate II Index Fund 14.67% | Apogee Therapeutics Inc 1.49% |
| Welltower Inc 7.86% | Moderna Inc 1.41% |
| Prologis Inc 7.02% | Twist Bioscience Corp 1.41% |
| Equinix Inc 5.66% | Oruka Therapeutics Inc 1.38% |
| American Tower Corp 4.55% | Kymera Therapeutics Inc 1.36% |
| Digital Realty Trust Inc 3.67% | Viking Therapeutics Inc 1.31% |
| Simon Property Group Inc 3.54% | Praxis Precision Medicines Inc 1.29% |
| Realty Income Corp 3.12% | Erasca Inc 1.27% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Apr 30, 2026 and Jun 30, 2026.
| VNQ Vanguard Real Estate Index Fund | XBI State Street(R) SPDR(R) S&P(R) Biotech ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | Vanguard | State Street |
| What it is | US real estate | SPDR S&P Biotech |
| Total return, 1 year | +5.6% | +64.0% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | −11.9 pts | +46.5 pts |
| Expense ratio | 0.13% | 0.35% |
| Already in the S&P 500 | 63.3% | 8.5% |
| Holdings | 146 | 150 |
VNQ in plain words
VNQ is an index equity fund tracking the US real estate. Over the year to Sep 11, 2026 it returned +5.6% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.13% a year. By its holdings filed for Apr 30, 2026, 63% of the fund by weight is stocks the S&P 500 also holds, across 146 positions, with the top ten at 54.9%. It sat 6.1% below its high of Jul 28, 2026 on Sep 11, 2026.
XBI in plain words
XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Jun 30, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 150 positions, with the top ten at 13.3%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, VNQ or XBI?
- In the year to Sep 12, 2026, with distributions reinvested, VNQ returned +5.6% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, VNQ or XBI?
- VNQ charges 0.13% a year and XBI charges 0.35%, so VNQ is cheaper. Fees come from each fund's prospectus.
- How much do VNQ and XBI overlap with the S&P 500?
- By their latest filed holdings, 63% of VNQ and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, VNQ against XBI, data as of Sep 12, 2026. https://etfiq.com/compare/any/VNQ-XBI Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources