Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
IVV vs XBI: how they differ
IVV and XBI hold 2% of their weight in the same names, and XBI returned more over the year.
iShares Core S&P 500 ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.
What they hold in common
By the books each fund has filed, IVV and XBI hold 2% of their money in the same securities at the same weight.
| Holding | IVV | XBI |
|---|---|---|
| AbbVie, Inc. | 0.69% | 1.04% |
| Amgen, Inc. | 0.30% | 1.00% |
| Gilead Sciences, Inc. | 0.24% | 0.97% |
| Vertex Pharmaceuticals, Inc. | 0.20% | 1.06% |
| Regeneron Pharmaceuticals, Inc. | 0.10% | 0.96% |
| Biogen, Inc. | 0.05% | 1.03% |
| Moderna, Inc. | 0.04% | 1.41% |
| Incyte Corp. | 0.03% | 1.00% |
| Only in IVV | Only in XBI |
|---|---|
| NVIDIA Corp. 7.52% | Apogee Therapeutics Inc 1.49% |
| Apple, Inc. 6.59% | Twist Bioscience Corp 1.41% |
| Microsoft Corp. 4.30% | Oruka Therapeutics Inc 1.38% |
| Amazon.com, Inc. 3.62% | Kymera Therapeutics Inc 1.36% |
| Alphabet, Inc. 3.25% | Viking Therapeutics Inc 1.31% |
| Broadcom, Inc. 2.77% | Praxis Precision Medicines Inc 1.29% |
| Alphabet, Inc. 2.59% | Erasca Inc 1.27% |
| Micron Technology, Inc. 2.02% | Revolution Medicines Inc 1.21% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026.
| IVV iShares Core S&P 500 ETF | XBI State Street(R) SPDR(R) S&P(R) Biotech ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | iShares | State Street |
| What it is | S&P 500 | SPDR S&P Biotech |
| Total return, 1 year | +17.6% | +64.0% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | +0.1 pts | +46.5 pts |
| Expense ratio | 0.03% | 0.35% |
| Already in the S&P 500 | 100.0% | 8.5% |
| Holdings | 504 | 150 |
IVV in plain words
IVV is an index equity fund tracking the S&P 500. Over the year to Sep 11, 2026 it returned +17.6% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.03% a year. By its holdings filed for Jun 30, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 504 positions, with the top ten at 36.4%.
XBI in plain words
XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Jun 30, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 150 positions, with the top ten at 13.3%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, IVV or XBI?
- In the year to Sep 12, 2026, with distributions reinvested, IVV returned +17.6% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, IVV or XBI?
- IVV charges 0.03% a year and XBI charges 0.35%, so IVV is cheaper. Fees come from each fund's prospectus.
- How much do IVV and XBI overlap with the S&P 500?
- By their latest filed holdings, 100% of IVV and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 2% of their books are the same securities at the same weight.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IVV against XBI, data as of Sep 12, 2026. https://etfiq.com/compare/any/IVV-XBI Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources