Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
IBB vs XLRE: how they differ
IBB and XLRE hold 0% of their weight in the same names, and IBB returned more over the year.
iShares Biotechnology ETF and State Street(R) Real Estate Select Sector SPDR(R) ETF.
What they hold in common
By the books each fund has filed, IBB and XLRE hold 0% of their money in the same securities at the same weight.
| Only in IBB | Only in XLRE |
|---|---|
| Vertex Pharmaceuticals, Inc. 8.09% | Welltower Inc 11.07% |
| Amgen, Inc. 7.84% | Prologis Inc 8.72% |
| Gilead Sciences, Inc. 6.85% | Equinix Inc 7.10% |
| Regeneron Pharmaceuticals, Inc. 4.91% | American Tower Corp 5.26% |
| Argenx SE 3.76% | Simon Property Group Inc 5.01% |
| Alnylam Pharmaceuticals, Inc. 3.12% | Realty Income Corp 4.57% |
| Natera, Inc. 2.89% | Digital Realty Trust Inc 4.55% |
| Revolution Medicines, Inc. 2.78% | Public Storage 4.51% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026.
| IBB iShares Biotechnology ETF | XLRE State Street(R) Real Estate Select Sector SPDR(R) ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | iShares | State Street |
| What it is | Biotechnology | Real estate |
| Total return, 1 year | +41.5% | +5.6% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | +24.0 pts | −11.9 pts |
| Expense ratio | 0.44% | 0.08% |
| Already in the S&P 500 | 35.6% | 100.0% |
| Holdings | 248 | 31 |
IBB in plain words
IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Jun 30, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 248 positions, with the top ten at 44.8%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.
XLRE in plain words
XLRE is an index equity fund tracking the Real estate. Over the year to Sep 11, 2026 it returned +5.6% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.08% a year. By its holdings filed for Jun 30, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 31 positions, with the top ten at 59.4%. It sat 5.6% below its high of Jul 28, 2026 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, IBB or XLRE?
- In the year to Sep 12, 2026, with distributions reinvested, IBB returned +41.5% and XLRE returned +5.6%, so IBB returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, IBB or XLRE?
- IBB charges 0.44% a year and XLRE charges 0.08%, so XLRE is cheaper. Fees come from each fund's prospectus.
- How much do IBB and XLRE overlap with the S&P 500?
- By their latest filed holdings, 36% of IBB and 100% of XLRE by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBB against XLRE, data as of Sep 12, 2026. https://etfiq.com/compare/any/IBB-XLRE Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources