Which returned more over the last year, IBB or VUSB?

In the year to Sep 12, 2026, with distributions reinvested, IBB returned +41.5% and VUSB returned +3.7%, so IBB returned more. One year is one year; the longer windows are in the table.

Which is cheaper, IBB or VUSB?

IBB charges 0.44% a year and VUSB charges 0.10%, so VUSB is cheaper. Fees come from each fund's prospectus.

Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.

ETFIQetfiq.com · independent ETF data

IBB vs VUSB: how they differ

IBB and VUSB hold 0% of their weight in the same names, and IBB returned more over the year.

iShares Biotechnology ETF and Vanguard Ultra-Short Bond ETF.

What they hold in common

By the books each fund has filed, IBB and VUSB hold 0% of their money in the same securities at the same weight.

Largest positions each one holds and the other does not
Only in IBB	Only in VUSB
Vertex Pharmaceuticals, Inc. 8.09%	United States Treasury Bill 4.24%
Amgen, Inc. 7.84%	United States Treasury Note/Bond 0.68%
Gilead Sciences, Inc. 6.85%	PNC Financial Services Group Inc/The 0.59%
Regeneron Pharmaceuticals, Inc. 4.91%	United States Treasury Note/Bond 0.53%
Argenx SE 3.76%	Regions Bank/Birmingham AL 0.52%
Alnylam Pharmaceuticals, Inc. 3.12%	US Bancorp 0.51%
Natera, Inc. 2.89%	Charles Schwab Corp/The 0.50%
Revolution Medicines, Inc. 2.78%	Truist Bank 0.45%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026.

IBB and VUSB on the fields both publish, as of Sep 12, 2026. Source: ETFIQ.
	IBB iShares Biotechnology ETF	VUSB Vanguard Ultra-Short Bond ETF
Where it sits	Core index fund	Core index fund
Issuer	iShares	Vanguard
What it is	Biotechnology	Ultra-Short Bond
Total return, 1 year	+41.5%	+3.7%
S&P 500 over the same days	+17.5%	+17.5%
Gap to the S&P 500	+24.0 pts	−13.8 pts
Expense ratio	0.44%	0.10%
Holdings	248	1281

IBB in plain words

IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Jun 30, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 248 positions, with the top ten at 44.8%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.

VUSB in plain words

VUSB is a cash and treasury bills tracking the Ultra-Short Bond. Over the year to Sep 11, 2026 it returned +3.7% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.10% a year.

Questions people ask

Which returned more over the last year, IBB or VUSB?: In the year to Sep 12, 2026, with distributions reinvested, IBB returned +41.5% and VUSB returned +3.7%, so IBB returned more. One year is one year; the longer windows are in the table.
Which is cheaper, IBB or VUSB?: IBB charges 0.44% a year and VUSB charges 0.10%, so VUSB is cheaper. Fees come from each fund's prospectus.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

IBB against VUSB, ETFIQ, data as of Sep 12, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, IBB against VUSB, data as of Sep 12, 2026. https://etfiq.com/compare/any/IBB-VUSB Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources