Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.
IBB vs VGSH: how they differ
IBB and VGSH hold 0% of their weight in the same names, and IBB returned more over the year.
iShares Biotechnology ETF and Vanguard Short-Term Treasury Index Fund.
What they hold in common
By the books each fund has filed, IBB and VGSH hold 0% of their money in the same securities at the same weight.
| Only in IBB | Only in VGSH |
|---|---|
| Vertex Pharmaceuticals, Inc. 8.09% | United States Treasury Note/Bond 2.26% |
| Amgen, Inc. 7.84% | United States Treasury Note/Bond 1.41% |
| Gilead Sciences, Inc. 6.85% | United States Treasury Note/Bond 1.36% |
| Regeneron Pharmaceuticals, Inc. 4.91% | United States Treasury Note/Bond 1.32% |
| Argenx SE 3.76% | United States Treasury Note/Bond 1.31% |
| Alnylam Pharmaceuticals, Inc. 3.12% | United States Treasury Note/Bond 1.30% |
| Natera, Inc. 2.89% | United States Treasury Note/Bond 1.27% |
| Revolution Medicines, Inc. 2.78% | United States Treasury Note/Bond 1.27% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and May 31, 2026.
| IBB iShares Biotechnology ETF | VGSH Vanguard Short-Term Treasury Index Fund | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | iShares | Vanguard |
| What it is | Biotechnology | Short-Term Treasury |
| Total return, 1 year | +41.5% | +1.8% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | +24.0 pts | −15.7 pts |
| Expense ratio | 0.44% | 0.03% |
| Holdings | 248 | 91 |
IBB in plain words
IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Jun 30, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 248 positions, with the top ten at 44.8%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.
VGSH in plain words
VGSH is a bond fund tracking the Short-Term Treasury. Over the year to Sep 11, 2026 it returned +1.8% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.03% a year.
Questions people ask
- Which returned more over the last year, IBB or VGSH?
- In the year to Sep 12, 2026, with distributions reinvested, IBB returned +41.5% and VGSH returned +1.8%, so IBB returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, IBB or VGSH?
- IBB charges 0.44% a year and VGSH charges 0.03%, so VGSH is cheaper. Fees come from each fund's prospectus.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBB against VGSH, data as of Sep 12, 2026. https://etfiq.com/compare/any/IBB-VGSH Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources