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Data as of Sep 12, 2026. Both funds on the fields they both publish, from the same sources.

ETFIQetfiq.com · independent ETF data

IBB vs MBB: how they differ

IBB and MBB hold 0% of their weight in the same names, and IBB returned more over the year.

iShares Biotechnology ETF and iShares MBS ETF.

What they hold in common

By the books each fund has filed, IBB and MBB hold 0% of their money in the same securities at the same weight.

Largest positions each one holds and the other does not
Only in IBBOnly in MBB
Vertex Pharmaceuticals, Inc. 8.09%Freddie Mac 1.07%
Amgen, Inc. 7.84%Government National Mortgage Association 0.97%
Gilead Sciences, Inc. 6.85%UMBS, TBA 0.85%
Regeneron Pharmaceuticals, Inc. 4.91%Government National Mortgage Association 0.69%
Argenx SE 3.76%UMBS, TBA 0.66%
Alnylam Pharmaceuticals, Inc. 3.12%Government National Mortgage Association 0.56%
Natera, Inc. 2.89%Government National Mortgage Association 0.55%
Revolution Medicines, Inc. 2.78%Government National Mortgage Association 0.54%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and May 31, 2026.

IBB and MBB on the fields both publish, as of Sep 12, 2026. Source: ETFIQ.
IBB
iShares Biotechnology ETF
MBB
iShares MBS ETF
Where it sitsCore index fundCore index fund
IssueriSharesiShares
What it isBiotechnologyMbs
Total return, 1 year+41.5%−0.1%
S&P 500 over the same days+17.5%+17.5%
Gap to the S&P 500+24.0 pts−17.6 pts
Expense ratio0.44%0.04%
Holdings24811144

IBB in plain words

IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Jun 30, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 248 positions, with the top ten at 44.8%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.

MBB in plain words

MBB is a bond fund tracking the Mbs. Over the year to Sep 11, 2026 it returned −0.1% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.04% a year. It sat 3.3% below its high of Feb 27, 2026 on Sep 11, 2026.

Questions people ask

Which returned more over the last year, IBB or MBB?
In the year to Sep 12, 2026, with distributions reinvested, IBB returned +41.5% and MBB returned −0.1%, so IBB returned more. One year is one year; the longer windows are in the table.
Which is cheaper, IBB or MBB?
IBB charges 0.44% a year and MBB charges 0.04%, so MBB is cheaper. Fees come from each fund's prospectus.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

IBB against MBB, ETFIQ, data as of Sep 12, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, IBB against MBB, data as of Sep 12, 2026. https://etfiq.com/compare/any/IBB-MBB Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources