Data as of .
Healthcare innovation and GLP-1 ETFs: what each one actually holds
5 funds, measured by holdings rather than by name. The typical fund carries 29% of its weight in S&P 500 names.
| Ticker | Fund | Issuer | In the S&P 500 | Active share | Total return 1Y | vs S&P 500 | Fee |
|---|---|---|---|---|---|---|---|
| OZEM | Roundhill GLP-1 & Weight Loss ETF | Roundhill | 24.8% | 97.8% | +28.9% | +9.0 pts | 0.59% |
| HELX | Franklin Genomic Advancements ETF | Franklin | 15.1% | 97.2% | +39.0% | +19.0 pts | 0.50% |
| HEAL | Global X HealthTech ETF | Global X | 28.9% | 99.5% | −6.5% | −26.4 pts | 0.50% |
| EKG | First Trust Nasdaq Lux Digital Health Solutions ETF | First Trust | 43.1% | 99.6% | +25.7% | +5.8 pts | 0.65% |
| THNR | Amplify Weight Loss Drug & Treatment ETF | Amplify | not published | not published | +18.1% | −1.9 pts | not published |
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Cite this page. ETFIQ, Healthcare innovation and GLP-1 ETFs: what each one actually holds, data as of Sep 4, 2026. https://etfiq.com/themes/health-innovation.html Free to use with attribution; the underlying files are at Open data.