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Ranked by active share against the S&P 500, latest holdings filing, as of . Rebuilt every trading night.

The thematic ETFs least like the S&P 500

Different is not better. It is how much of the fund a holder did not already own through the index.

The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500, as of Sep 4, 2026. Source: ETFIQ.
#TickerFundThemeActive shareIn the S&P 500Total return 1Yvs S&P 500
1DRAIDraco Evolution AI ETFArtificial intelligence100.0%0.0%+21.7%+1.7 pts
2DRGNThemes China Generative Artificial Intelligence ETFArtificial intelligence100.0%0.0%+12.3%−7.6 pts
3GXDWGlobal X Dorsey Wright Thematic ETFBroad innovation and megatrends100.0%0.0%−7.2%−27.2 pts
4LFSCF/m Emerald Life Sciences Innovation ETFBroad innovation and megatrends100.0%0.0%+61.7%+41.7 pts
5CNBSAmplify Seymour Cannabis ETFCannabis100.0%0.0%+3.3%−16.6 pts
6MSOSAdvisorShares Pure US Cannabis ETFCannabis100.0%0.0%+11.6%−8.4 pts
7WEEDRoundhill Cannabis ETFCannabis100.0%0.0%+14.2%−5.7 pts
8ICLNiShares Global Clean Energy ETFClean energy100.0%7.2%+25.3%+5.3 pts
9KGRNKraneShares MSCI China Clean Technology Index ETFClean energy100.0%0.0%−18.7%−38.6 pts
10RNRGGlobal X Renewable Energy Producers ETFClean energy100.0%0.0%+15.5%−4.4 pts
11TANInvesco Solar ETFClean energy100.0%11.7%+14.3%−5.6 pts
12EUADSelect STOXX Europe Aerospace & Defense ETFDefense100.0%0.0%+4.2%−15.8 pts
13KDEFPLUS Korea Defense Industry Index ETFDefense100.0%0.0%+1.2%−18.8 pts
14WDAFWisdomTree Asia Defense FundDefense100.0%0.0%not publishednot available
15WDEFWisdomTree Europe Defense FundDefense100.0%0.0%+0.8%−19.1 pts

Method

Active share is one hundred minus the weight overlap with the S&P 500 book, computed by ETFIQ from filed holdings. The ranking is the published field sorted, nothing else: no scoring, no weighting and no view on any fund. Every fund ETFIQ covers in this category is eligible, including funds that have closed, because leaving them out would flatter the category.

Where to next

A ranking is not a recommendation and no order on this site is an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources

Cite this page. ETFIQ, The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500, data as of Sep 4, 2026. https://etfiq.com/rankings/themes-least-index.html Free to use with attribution; the underlying files are at Open data.