# Health care sector ETFs: all 23, largest first > 23 Health care sector ETFs placed by ETFIQ from their own filings, each with one-year return, its gap to the S&P 500, fee and net assets, as of Oct 2 Data as of Oct 2, 2026. Rebuilt every trading night. Rebuilt every trading night. Figures as of Oct 2, 2026 . ## Health care sector ETFs: all 23 23 health care sector ETFs, placed by ETFIQ from each fund’s own filings. Concentrated in drug makers, biotechnology, medical devices and health services. Each is listed with its one-year return, its gap to the S&P 500, its fee and its net assets. ### On other desks ### The 10 largest health care sector ETFs ETFIQ covers 23 health care sector ETFs. The largest are XLV ( $42.7bn ), VHT ( $19.1bn ) and IXJ ( $4.3bn ); fees run 0.08% to 0.85% , as of Sep 30 to Oct 2, 2026 . - XLV State Street Health Care Select Sector SPDR ETF $42.7bn 0.08% - VHT Vanguard Health Care ETF $19.1bn 0.09% - IXJ iShares Global Healthcare ETF $4.3bn 0.38% - IYH iShares U.S. Healthcare ETF $3.9bn 0.37% - FHLC Fidelity MSCI Health Care Index ETF $3.5bn 0.08% - IHE iShares U.S. Pharmaceuticals ETF $1.6bn 0.37% - IHF iShares U.S. Healthcare Providers ETF $1.4bn 0.37% - FXH First Trust Health Care AlphaDEX Fund $1.1bn 0.61% - FTXH First Trust Nasdaq Pharmaceuticals ETF $1.0bn 0.60% - RSPH Invesco S&P 500 Equal Weight Health Care ETF $875m 0.40% ### Every health care sector ETF, largest first | Ticker | Fund | Tracks | Total return 1Y | vs S&P 500 1Y | Fee | Net assets | | --- | --- | --- | --- | --- | --- | --- | | XLV | State Street Health Care Select Sector SPDR ETF | Health care | +18.0% | +1.7 pts | 0.08% | $42.7bn | | VHT | Vanguard Health Care ETF | Health Care | +18.9% | +2.7 pts | 0.09% | $19.1bn | | IXJ | iShares Global Healthcare ETF | not read by ETFIQ | +11.8% | −4.4 pts | 0.38% | $4.3bn | | IYH | iShares U.S. Healthcare ETF | not read by ETFIQ | +17.9% | +1.7 pts | 0.37% | $3.9bn | | FHLC | Fidelity MSCI Health Care Index ETF | not read by ETFIQ | +19.1% | +2.8 pts | 0.08% | $3.5bn | | IHE | iShares U.S. Pharmaceuticals ETF | not read by ETFIQ | +34.4% | +18.1 pts | 0.37% | $1.6bn | | IHF | iShares U.S. Healthcare Providers ETF | not read by ETFIQ | +11.6% | −4.7 pts | 0.37% | $1.4bn | | FXH | First Trust Health Care AlphaDEX Fund | not read by ETFIQ | +15.8% | −0.4 pts | 0.61% | $1.1bn | | FTXH | First Trust Nasdaq Pharmaceuticals ETF | not read by ETFIQ | +39.1% | +22.9 pts | 0.60% | $1.0bn | | RSPH | Invesco S&P 500 Equal Weight Health Care ETF | not read by ETFIQ | +22.3% | +6.1 pts | 0.40% | $875m | | PJP | Invesco Pharmaceuticals ETF | not read by ETFIQ | +29.4% | +13.1 pts | 0.58% | $545m | | XPH | State Street SPDR S&P Pharmaceuticals ETF | not read by ETFIQ | +32.5% | +16.2 pts | 0.35% | $510m | | PINK | Simplify Health Care ETF | No index (active) | +17.6% | +1.3 pts | 0.51% | $342m | | PTH | Invesco Dorsey Wright Healthcare Momentum ETF | not read by ETFIQ | +38.8% | +22.5 pts | 0.60% | $292m | | XHS | State Street SPDR S&P Health Care Services ETF | not read by ETFIQ | +31.7% | +15.4 pts | 0.35% | $219m | | XHE | State Street SPDR S&P Health Care Equipment ETF | not read by ETFIQ | +12.1% | −4.2 pts | 0.35% | $181m | | PSCH | Invesco S&P SmallCap Health Care ETF | not read by ETFIQ | +22.3% | +6.1 pts | 0.29% | $175m | | SBIO | ALPS Medical Breakthroughs ETF | not read by ETFIQ | +43.9% | +27.7 pts | 0.50% | $162m | | HRTS | Tema Heart & Health ETF | No index (active) | +13.8% | −2.4 pts | 0.75% | $53m | | MEDI | Harbor Health Care ETF | No index (active) | +11.4% | −4.8 pts | 0.80% | $41m | | TMED | T. Rowe Price Health Care ETF | No index (active) | +21.4% | +5.2 pts | 0.44% | $23m | | MEDX | Horizon Kinetics Medical ETF | No index (active) | +11.3% | −5.0 pts | 0.85% | $19m | | JDOC | JPMorgan Healthcare Leaders ETF | No index (active) | +11.6% | −4.6 pts | 0.65% | $9m | ### Where to next Cite this page. ETFIQ, Health care sector ETFs: all 23, data as of Oct 2, 2026. https://etfiq.com/stocks/health/ Free to use with attribution ; the underlying files are at Open data . Other forms Plain ETFIQ, Health care sector ETFs: all 23, data as of Oct 2, 2026. https://etfiq.com/stocks/health/ APA ETFIQ. (Oct 2, 2026). Health care sector ETFs: all 23. Retrieved from https://etfiq.com/stocks/health/ Markdown [Health care sector ETFs: all 23 (ETFIQ, Oct 2, 2026)](https://etfiq.com/stocks/health/) --- Source: ETFIQ, independent ETF data. Recomputed nightly from public filings and prices. Cite: ETFIQ, as of Oct 2, 2026. https://etfiq.com/stocks/health License: https://etfiq.com/standards/ HTML: https://etfiq.com/stocks/health