{"url":"https://etfiq.com/rankings/themes-off-index-innovation","section":"rankings","title":"The innovation ETFs least like the S&P 500 | ETFIQ","description":"GXDW leads the innovation ETFs least like the S&P 500 at 0.0% (weight in S&P 500 companies), as of Nov 4, 2026. A ranking is not a recommendation.","as_of":"Nov 4, 2026","structured_data":[{"@type":"ItemList","name":"The innovation ETFs least like the S&P 500","numberOfItems":15,"itemListOrder":"https://schema.org/ItemListOrderDescending","itemListElement":[{"@type":"ListItem","position":1,"name":"GXDW","url":"https://etfiq.com/funds/gxdw"},{"@type":"ListItem","position":2,"name":"LFSC","url":"https://etfiq.com/funds/lfsc"},{"@type":"ListItem","position":3,"name":"LENS","url":"https://etfiq.com/funds/lens"},{"@type":"ListItem","position":4,"name":"FMED","url":"https://etfiq.com/funds/fmed"},{"@type":"ListItem","position":5,"name":"FITE","url":"https://etfiq.com/funds/fite"},{"@type":"ListItem","position":6,"name":"INVN","url":"https://etfiq.com/funds/invn"},{"@type":"ListItem","position":7,"name":"HTEC","url":"https://etfiq.com/funds/htec"},{"@type":"ListItem","position":8,"name":"GTEK","url":"https://etfiq.com/funds/gtek"},{"@type":"ListItem","position":9,"name":"ARKK","url":"https://etfiq.com/funds/arkk"},{"@type":"ListItem","position":10,"name":"BULD","url":"https://etfiq.com/funds/buld"},{"@type":"ListItem","position":11,"name":"DTEC","url":"https://etfiq.com/funds/dtec"},{"@type":"ListItem","position":12,"name":"DTRE","url":"https://etfiq.com/funds/dtre"},{"@type":"ListItem","position":13,"name":"FDFF","url":"https://etfiq.com/funds/fdff"},{"@type":"ListItem","position":14,"name":"QQQJ","url":"https://etfiq.com/funds/qqqj"},{"@type":"ListItem","position":15,"name":"TMAT","url":"https://etfiq.com/funds/tmat"}]},{"@type":"Dataset","name":"The innovation ETFs least like the S&P 500","description":"GXDW leads the innovation ETFs least like the S&P 500 at 0.0% (weight in S&P 500 companies), as of Nov 4, 2026. A ranking is not a recommendation.","url":"https://etfiq.com/rankings/themes-off-index-innovation","dateModified":"2026-11-04","creator":{"@id":"https://etfiq.com/#org"},"license":"https://etfiq.com/license/","isAccessibleForFree":true,"creditText":"ETFIQ (etfiq.com)","publisher":{"@id":"https://etfiq.com/#org"},"inLanguage":"en","creativeWorkStatus":"Published","distribution":[{"@type":"DataDownload","encodingFormat":"application/json","contentUrl":"https://etfiq.com/data/thematic.json"}],"variableMeasured":["Weight overlap with the S&P 500","Active share","Holdings","Top ten share of the fund","Total return","Fee for the differing part","Expense ratio"],"keywords":["exchange-traded funds","ETF","Thematic ETFs","fund data","SEC filings"]},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"ETFIQ","item":"https://etfiq.com/"},{"@type":"ListItem","position":2,"name":"Rankings","item":"https://etfiq.com/rankings/"},{"@type":"ListItem","position":3,"name":"The innovation ETFs least like the S&P 500","item":"https://etfiq.com/rankings/themes-off-index-innovation"}]},{"@type":"WebPage","name":"The innovation ETFs least like the S&P 500","description":"GXDW leads the innovation ETFs least like the S&P 500 at 0.0% (weight in S&P 500 companies), as of Nov 4, 2026. A ranking is not a recommendation.","url":"https://etfiq.com/rankings/themes-off-index-innovation","dateModified":"2026-11-04","isPartOf":{"@type":"WebSite","name":"ETFIQ","url":"https://etfiq.com"},"speakable":{"@type":"SpeakableSpecification","cssSelector":[".lede"]},"publisher":{"@id":"https://etfiq.com/#org"}}],"characters":3579,"truncated":false,"content":"ETFIQ / Rankings / The innovation ETFs least like the S&P 500 \n \n As of Nov 4, 2026 . Rebuilt every trading night.\n The innovation ETFs least like the S&P 500\n See 15 funds ranked by the share of each fund held in S&P 500 companies. Updated Nov 4, 2026. Every fund here is sold on innovation. The one at the top holds the least of the S&P 500, so it adds the most you do not already own.\n The innovation ETFs least like the S&P 500, ranked by the share of each fund held in S&P 500 companies, as of Nov 4, 2026. Source: ETFIQ. # Ticker Fund Weight in S&P 500 companies Active share Net assets Fee \n 1 GXDW Global X Dorsey Wright Thematic ETF 0.0% 100.0% $6.0m 0.50% \n 2 LFSC F/m Emerald Life Sciences Innovation ETF 0.0% 100.0% $126m 0.54% \n 3 LENS Sarmaya Thematic ETF 16.0% 98.9% $67m 0.79% \n 4 FMED Fidelity Disruptive Medicine ETF 21.8% 97.5% $52m 0.50% \n 5 FITE State Street SPDR S&P Kensho Future Secu 26.9% 95.3% $153m 0.45% \n 6 INVN Alger Russell Innovation ETF 32.5% 98.5% $9.6m 0.55% \n 7 HTEC ROBO Global Healthcare Technology and In 32.7% 97.9% $69m 0.68% \n 8 GTEK Goldman Sachs Future Tech Leaders Equity 33.0% 96.5% $209m 0.75% \n 9 ARKK ARK Innovation ETF 36.2% 85.7% $5.9bn 0.75% \n 10 BULD Pacer BlueStar Engineering the Future ET 36.4% 97.3% $8.6m 0.49% \n 11 DTEC ALPS Disruptive Technologies ETF 41.3% 93.5% $78m 0.50% \n 12 DTRE First Trust Alerian Disruptive Technolog 43.0% 99.4% $14m 0.60% \n 13 FDFF Fidelity Disruptive Finance ETF 43.4% 97.5% $43m 0.50% \n 14 QQQJ Invesco NASDAQ Next Gen 100 ETF 46.7% 98.6% $1.2bn 0.15% \n 15 TMAT Main Thematic Innovation ETF 50.3% 91.6% $237m 0.79% \n \n Method\n The 29 of 30 ETFs in the broad innovation and megatrends theme with a filed book, least overlap first, each measured against the S&P 500 holdings ETFIQ reads for the same date. Across the funds listed here the weight held in S&P 500 companies runs from 0.0% to 50.3%. A thematic fund is worth its fee only for the part of it you do not already own. The list sorts one published number, with no scoring or weighting. Every fund ETFIQ covers in this category is eligible, closed funds included.\n Where to next\n Every innovation ETF and what it holds The largest innovation ETFs Sources\n Fund holdings from SEC Form N-PORT and from the issuers\u2019 own daily files SEC EDGAR, full-text search of fund filings SEC Form N-PORT, what a fund filed it holds Rule 19a-1, what a distribution notice must say Links are sources, not endorsements.\n A ranking is not a recommendation or an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources \n Cite this page. ETFIQ, The innovation ETFs least like the S&P 500, ranked by the share of each fund held in S&P 500 companies, data as of Nov 4, 2026. https://etfiq.com/rankings/themes-off-index-innovation Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data .\n Other forms Plain ETFIQ, The innovation ETFs least like the S&P 500, ranked by the share of each fund held in S&P 500 companies, data as of Nov 4, 2026. https://etfiq.com/rankings/themes-off-index-innovation APA ETFIQ. (Nov 4, 2026). The innovation ETFs least like the S&P 500, ranked by the share of each fund held in S&P 500 companies. Retrieved from https://etfiq.com/rankings/themes-off-index-innovation Markdown [The innovation ETFs least like the S&P 500, ranked by the share of each fund held in S&P 500 companies (ETFIQ, Nov 4, 2026)](https://etfiq.com/rankings/themes-off-index-innovation)","source":"ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.","publisher":{"@id":"https://etfiq.com/#org","name":"ETFIQ","url":"https://etfiq.com"},"license":"https://etfiq.com/license/","license_text":"Data ETFIQ computes is free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.","citation":"ETFIQ, The innovation ETFs least like the S&P 500, ranked by the share of each fund held in S&P 500 companies, data as of Nov 4, 2026. https://etfiq.com/rankings/themes-off-index-innovation"}