{"url":"https://etfiq.com/rankings/themes-least-index","section":"rankings","title":"The thematic ETFs least like the S&P 500 | ETFIQ","description":"PDBA leads the thematic ETFs least like the S&P 500 at 100.0% (active share, latest holdings filing), as of Oct 27, 2026.","as_of":"Oct 27, 2026","structured_data":[{"@type":"ItemList","name":"The thematic ETFs least like the S&P 500","numberOfItems":15,"itemListOrder":"https://schema.org/ItemListOrderDescending","itemListElement":[{"@type":"ListItem","position":1,"name":"PDBA","url":"https://etfiq.com/funds/pdba"},{"@type":"ListItem","position":2,"name":"DRAI","url":"https://etfiq.com/funds/drai"},{"@type":"ListItem","position":3,"name":"DRGN","url":"https://etfiq.com/funds/drgn"},{"@type":"ListItem","position":4,"name":"KAIT","url":"https://etfiq.com/funds/kait"},{"@type":"ListItem","position":5,"name":"BBC","url":"https://etfiq.com/funds/bbc"},{"@type":"ListItem","position":6,"name":"GXDW","url":"https://etfiq.com/funds/gxdw"},{"@type":"ListItem","position":7,"name":"LFSC","url":"https://etfiq.com/funds/lfsc"},{"@type":"ListItem","position":8,"name":"MJ","url":"https://etfiq.com/funds/mj"},{"@type":"ListItem","position":9,"name":"MSOS","url":"https://etfiq.com/funds/msos"},{"@type":"ListItem","position":10,"name":"WEED","url":"https://etfiq.com/funds/weed"},{"@type":"ListItem","position":11,"name":"YOLO","url":"https://etfiq.com/funds/yolo"},{"@type":"ListItem","position":12,"name":"CTEC","url":"https://etfiq.com/funds/ctec"},{"@type":"ListItem","position":13,"name":"ICLN","url":"https://etfiq.com/funds/icln"},{"@type":"ListItem","position":14,"name":"KGRN","url":"https://etfiq.com/funds/kgrn"},{"@type":"ListItem","position":15,"name":"RNRG","url":"https://etfiq.com/funds/rnrg"}]},{"@type":"Dataset","name":"The thematic ETFs least like the S&P 500","description":"PDBA leads the thematic ETFs least like the S&P 500 at 100.0% (active share, latest holdings filing), as of Oct 27, 2026.","url":"https://etfiq.com/rankings/themes-least-index","dateModified":"2026-10-27","creator":{"@id":"https://etfiq.com/#org"},"license":"https://etfiq.com/license/","isAccessibleForFree":true,"creditText":"ETFIQ (etfiq.com)","publisher":{"@id":"https://etfiq.com/#org"},"inLanguage":"en","creativeWorkStatus":"Published","distribution":[{"@type":"DataDownload","encodingFormat":"application/json","contentUrl":"https://etfiq.com/data/thematic.json"}],"variableMeasured":["Weight overlap with the S&P 500","Active share","Holdings","Top ten share of the fund","Total return","Fee for the differing part","Expense ratio"],"keywords":["exchange-traded funds","ETF","Thematic ETFs","fund data","SEC filings"]},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"ETFIQ","item":"https://etfiq.com/"},{"@type":"ListItem","position":2,"name":"Rankings","item":"https://etfiq.com/rankings/"},{"@type":"ListItem","position":3,"name":"The thematic ETFs least like the S&P 500","item":"https://etfiq.com/rankings/themes-least-index"}]},{"@type":"WebPage","name":"The thematic ETFs least like the S&P 500","description":"PDBA leads the thematic ETFs least like the S&P 500 at 100.0% (active share, latest holdings filing), as of Oct 27, 2026.","url":"https://etfiq.com/rankings/themes-least-index","dateModified":"2026-10-27","isPartOf":{"@type":"WebSite","name":"ETFIQ","url":"https://etfiq.com"},"speakable":{"@type":"SpeakableSpecification","cssSelector":[".lede"]},"publisher":{"@id":"https://etfiq.com/#org"}}],"characters":3743,"truncated":false,"content":"ETFIQ / Rankings / The thematic ETFs least like the S&P 500 \n \n As of Oct 27, 2026 . Rebuilt every trading night.\n The thematic ETFs least like the S&P 500\n See 15 funds ranked by active share against the S&P 500, latest holdings filing. Updated Oct 27, 2026. Different is not better. It is how much of the fund a holder did not already own through the index. The top 15 are level at 100.0%, so their order is not a ranking. None of them holds anything the S&P 500 holds.\n The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500, as of Oct 27, 2026. Source: ETFIQ. # Ticker Fund Theme Active share In the S&P 500 Total return 1Y vs its benchmark 1Y \n 1 PDBA Invesco Agriculture Commodity Strategy No K-1 ETF Agriculture 100.0% 0.0% +8.2% not measured \n 2 DRAI Draco Evolution AI ETF Artificial intelligence 100.0% 0.0% +7.5% \u22125.4 pts vs GUSA \n 3 DRGN Themes China Generative Artificial Intelligence ETF Artificial intelligence 100.0% 0.0% \u221220.7% \u221233.8 pts vs ACWI \n 4 KAIT KraneShares Asia AI Technology ETF Artificial intelligence 100.0% 0.0% not published not available \n 5 BBC Virtus Biotech Clinical Trials ETF Biotech 100.0% 0.0% +36.6% not measured \n 6 GXDW Global X Dorsey Wright Thematic ETF Broad innovation and megatrends 100.0% 0.0% \u221210.8% not measured \n 7 LFSC F/m Emerald Life Sciences Innovation ETF Broad innovation and megatrends 100.0% 0.0% +35.8% +22.7 pts vs IWV \n 8 MJ Amplify Alternative Harvest ETF Cannabis 100.0% 0.0% \u221232.6% not measured \n 9 MSOS AdvisorShares Pure US Cannabis ETF Cannabis 100.0% 0.0% \u221212.0% not measured \n 10 WEED Roundhill Cannabis ETF Cannabis 100.0% 0.0% \u22121.5% not measured \n 11 YOLO AdvisorShares Pure Cannabis ETF Cannabis 100.0% 0.0% \u221221.1% not measured \n 12 CTEC Global X ClimateTech ETF Clean energy 100.0% 7.1% \u221210.0% not measured \n 13 ICLN iShares Global Clean Energy ETF Clean energy 100.0% 8.2% \u22124.3% not measured \n 14 KGRN KraneShares MSCI China Clean Technology Index ETF Clean energy 100.0% 0.0% \u221230.9% not measured \n 15 RNRG Global X Renewable Energy Producers ETF Clean energy 100.0% 0.0% \u22125.1% \u221218.2 pts vs ACWI \n \n Method\n Active share is one hundred minus the weight overlap with the S&P 500 book, computed by ETFIQ from filed holdings. The list sorts one published number, with no scoring or weighting. Every fund ETFIQ covers in this category is eligible, closed funds included.\n Where to next\n Every thematic ETF The thematic ETFs that are mostly the index already Sources\n Fund holdings from SEC Form N-PORT and from the issuers\u2019 own daily files SEC EDGAR, full-text search of fund filings SEC Form N-PORT, what a fund filed it holds Rule 19a-1, what a distribution notice must say Links are sources, not endorsements.\n A ranking is not a recommendation or an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources \n Cite this page. ETFIQ, The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500, data as of Oct 27, 2026. https://etfiq.com/rankings/themes-least-index Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data .\n Other forms Plain ETFIQ, The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500, data as of Oct 27, 2026. https://etfiq.com/rankings/themes-least-index APA ETFIQ. (Oct 27, 2026). The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500. Retrieved from https://etfiq.com/rankings/themes-least-index Markdown [The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500 (ETFIQ, Oct 27, 2026)](https://etfiq.com/rankings/themes-least-index)","source":"ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.","publisher":{"@id":"https://etfiq.com/#org","name":"ETFIQ","url":"https://etfiq.com"},"license":"https://etfiq.com/license/","license_text":"Data ETFIQ computes is free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.","citation":"ETFIQ, The thematic ETFs least like the S&P 500, ranked by active share against the S&P 500, data as of Oct 27, 2026. https://etfiq.com/rankings/themes-least-index"}