{"url":"https://etfiq.com/rankings/themes-largest-therapeutics","section":"rankings","title":"The largest therapeutics and medical devices ETFs | ETFIQ","description":"The largest therapeutics and medical devices ETFs, ranked by net assets, as of Oct 20, 2026. 5 funds from ETFIQ\u2019s own published figures.","as_of":"Oct 20, 2026","structured_data":[{"@type":"ItemList","name":"The largest therapeutics and medical devices ETFs","numberOfItems":5,"itemListOrder":"https://schema.org/ItemListOrderDescending","itemListElement":[{"@type":"ListItem","position":1,"name":"IHI","url":"https://etfiq.com/funds/ihi"},{"@type":"ListItem","position":2,"name":"CANC","url":"https://etfiq.com/funds/canc"},{"@type":"ListItem","position":3,"name":"PSIL","url":"https://etfiq.com/funds/psil"},{"@type":"ListItem","position":4,"name":"IBRN","url":"https://etfiq.com/funds/ibrn"},{"@type":"ListItem","position":5,"name":"MDEV","url":"https://etfiq.com/funds/mdev"}]},{"@type":"Dataset","name":"The largest therapeutics and medical devices ETFs","description":"The largest therapeutics and medical devices ETFs, ranked by net assets, as of Oct 20, 2026. 5 funds from ETFIQ\u2019s own published figures.","url":"https://etfiq.com/rankings/themes-largest-therapeutics","dateModified":"2026-10-20","creator":{"@id":"https://etfiq.com/#org"},"license":"https://etfiq.com/license/","isAccessibleForFree":true,"creditText":"ETFIQ (etfiq.com)","publisher":{"@id":"https://etfiq.com/#org"},"inLanguage":"en","creativeWorkStatus":"Published","distribution":[{"@type":"DataDownload","encodingFormat":"application/json","contentUrl":"https://etfiq.com/data/thematic.json"}],"variableMeasured":["Weight overlap with the S&P 500","Active share","Holdings","Top ten share of the fund","Total return","Fee for the differing part","Expense ratio"],"keywords":["exchange-traded funds","ETF","Thematic ETFs","fund data","SEC filings"]},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"ETFIQ","item":"https://etfiq.com/"},{"@type":"ListItem","position":2,"name":"Rankings","item":"https://etfiq.com/rankings/"},{"@type":"ListItem","position":3,"name":"The largest therapeutics and medical devic...","item":"https://etfiq.com/rankings/themes-largest-therapeutics"}]},{"@type":"WebPage","name":"The largest therapeutics and medical devices ETFs","description":"The largest therapeutics and medical devices ETFs, ranked by net assets, as of Oct 20, 2026. 5 funds from ETFIQ\u2019s own published figures.","url":"https://etfiq.com/rankings/themes-largest-therapeutics","dateModified":"2026-10-20","isPartOf":{"@type":"WebSite","name":"ETFIQ","url":"https://etfiq.com"},"speakable":{"@type":"SpeakableSpecification","cssSelector":[".lede"]},"publisher":{"@id":"https://etfiq.com/#org"}}],"characters":2854,"truncated":false,"content":"ETFIQ / Rankings / The largest therapeutics and medical devic... \n \n As of Oct 20, 2026 . Rebuilt every trading night.\n The largest therapeutics and medical devices ETFs\n See 5 funds ranked by net assets. Updated Oct 20, 2026. Every fund here is sold on therapeutics and medical devices. What each one holds, and how much of it the S&P 500 already holds for you, is the column beside the size.\n The largest therapeutics and medical devices ETFs, ranked by net assets, as of Oct 20, 2026. Source: ETFIQ. # Ticker Fund Net assets Weight in S&P 500 companies Total return, 1Y Fee Source \n 1 IHI iShares U.S. Medical Devices ETF $3.5bn 88.5% \u221210.1% 0.37% Issuer daily, Oct 20, 2026 \n 2 CANC Tema Oncology ETF $204m 21.9% +36.5% 0.75% Issuer page, Oct 19, 2026 \n 3 PSIL AdvisorShares Psychedelics ETF $46m 7.8% +7.0% 1.00% Issuer page, Oct 20, 2026 \n 4 IBRN iShares Neuroscience and Healthcare ETF $6m 5.3% +9.3% 0.47% Issuer daily, Oct 20, 2026 \n 5 MDEV First Trust Indxx Medical Devices ETF $3m 47.4% +4.4% 0.70% Issuer page, Oct 20, 2026 \n \n Method\n The 5 ETFs in the therapeutics and medical devices theme, of which 5 publish net assets, ranked on the most recent figure for each. Across the funds listed here the weight held in S&P 500 companies runs from 5.3% to 88.5%. Size shows where the money is, not what a fund did. The list sorts one published figure, with no scoring or weighting. Every fund ETFIQ covers in this category is eligible, closed funds included.\n Where to next\n Every therapeutics and medical devices ETF and what it holds The thematic ETFs least like the S&P 500 Where these figures came from\n Fund holdings from SEC Form N-PORT and from the issuers own daily files SEC EDGAR, full-text search of fund filings SEC Form N-PORT, what a fund filed it holds Rule 19a-1, what a distribution notice must say ETFIQ links to the documents behind every figure; a link is not an endorsement.\n A ranking is not a recommendation or an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources \n Cite this page. ETFIQ, The largest therapeutics and medical devices ETFs, ranked by net assets, data as of Oct 20, 2026. https://etfiq.com/rankings/themes-largest-therapeutics Free to use with attribution for figures ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data .\n Other forms Plain ETFIQ, The largest therapeutics and medical devices ETFs, ranked by net assets, data as of Oct 20, 2026. https://etfiq.com/rankings/themes-largest-therapeutics APA ETFIQ. (Oct 20, 2026). The largest therapeutics and medical devices ETFs, ranked by net assets. Retrieved from https://etfiq.com/rankings/themes-largest-therapeutics Markdown [The largest therapeutics and medical devices ETFs, ranked by net assets (ETFIQ, Oct 20, 2026)](https://etfiq.com/rankings/themes-largest-therapeutics)","source":"ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.","publisher":{"@id":"https://etfiq.com/#org","name":"ETFIQ","url":"https://etfiq.com"},"license":"https://etfiq.com/license/","license_text":"Figures ETFIQ computes are free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.","citation":"ETFIQ, The largest therapeutics and medical devices ETFs, ranked by net assets, data as of Oct 20, 2026. https://etfiq.com/rankings/themes-largest-therapeutics"}