{"url":"https://etfiq.com/rankings/themes-concentrated-biotech","section":"rankings","title":"Biotech ETFs: 9 Ranked by Top-10 Weight, Nov 2026 | ETFIQ","description":"9 biotech ETFs ranked by weight in their ten largest holdings, as of Nov 4, 2026. BBH leads at 73.5% in its ten largest. Rebuilt every trading night.","as_of":"Nov 4, 2026","structured_data":[{"@type":"ItemList","name":"The most concentrated biotech ETFs","numberOfItems":9,"itemListOrder":"https://schema.org/ItemListOrderDescending","itemListElement":[{"@type":"ListItem","position":1,"name":"BBH","url":"https://etfiq.com/funds/bbh"},{"@type":"ListItem","position":2,"name":"PBPH","url":"https://etfiq.com/funds/pbph"},{"@type":"ListItem","position":3,"name":"IBB","url":"https://etfiq.com/funds/ibb"},{"@type":"ListItem","position":4,"name":"PBE","url":"https://etfiq.com/funds/pbe"},{"@type":"ListItem","position":5,"name":"IBBQ","url":"https://etfiq.com/funds/ibbq"},{"@type":"ListItem","position":6,"name":"FBT","url":"https://etfiq.com/funds/fbt"},{"@type":"ListItem","position":7,"name":"BBP","url":"https://etfiq.com/funds/bbp"},{"@type":"ListItem","position":8,"name":"XBI","url":"https://etfiq.com/funds/xbi"},{"@type":"ListItem","position":9,"name":"BBC","url":"https://etfiq.com/funds/bbc"}]},{"@type":"Dataset","name":"The most concentrated biotech ETFs","description":"9 biotech ETFs ranked by weight in their ten largest holdings, as of Nov 4, 2026. BBH leads at 73.5% in its ten largest. Rebuilt every trading night.","url":"https://etfiq.com/rankings/themes-concentrated-biotech","dateModified":"2026-11-04","creator":{"@id":"https://etfiq.com/#org"},"license":"https://etfiq.com/license/","isAccessibleForFree":true,"creditText":"ETFIQ (etfiq.com)","publisher":{"@id":"https://etfiq.com/#org"},"inLanguage":"en","creativeWorkStatus":"Published","distribution":[{"@type":"DataDownload","encodingFormat":"application/json","contentUrl":"https://etfiq.com/data/thematic.json"}],"variableMeasured":["Weight overlap with the S&P 500","Active share","Holdings","Top ten share of the fund","Total return","Fee for the differing part","Expense ratio"],"keywords":["exchange-traded funds","ETF","Thematic ETFs","fund data","SEC filings"]},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"ETFIQ","item":"https://etfiq.com/"},{"@type":"ListItem","position":2,"name":"Rankings","item":"https://etfiq.com/rankings/"},{"@type":"ListItem","position":3,"name":"The most concentrated biotech ETFs","item":"https://etfiq.com/rankings/themes-concentrated-biotech"}]},{"@type":"WebPage","name":"Biotech ETFs: 9 Ranked by Top-10 Weight, Nov 2026","description":"9 biotech ETFs ranked by weight in their ten largest holdings, as of Nov 4, 2026. BBH leads at 73.5% in its ten largest. Rebuilt every trading night.","url":"https://etfiq.com/rankings/themes-concentrated-biotech","dateModified":"2026-11-04","isPartOf":{"@type":"WebSite","name":"ETFIQ","url":"https://etfiq.com"},"speakable":{"@type":"SpeakableSpecification","cssSelector":[".lede"]},"publisher":{"@id":"https://etfiq.com/#org"}}],"characters":2953,"truncated":false,"content":"ETFIQ / Rankings / The most concentrated biotech ETFs \n \n As of Nov 4, 2026 . Rebuilt every trading night.\n The most concentrated biotech ETFs\n See 9 funds ranked by the share of the fund held in its ten largest positions. Updated Nov 4, 2026. Two funds on one theme can hold ten names or two hundred. Fund names do not show which.\n The most concentrated biotech ETFs, ranked by the share of the fund held in its ten largest positions, as of Nov 4, 2026. Source: ETFIQ. # Ticker Fund Top ten weight Holdings Net assets Total return, 1Y \n 1 BBH VanEck Biotech ETF 73.5% 25 $525m +47.2% \n 2 PBPH Portfolio Building Block World Pharma an 61.9% 53 $952m too new \n 3 IBB iShares Biotechnology ETF 51.6% 245 $11.2bn +42.0% \n 4 PBE Invesco Biotechnology & Genome ETF 49.1% 32 $442m +44.2% \n 5 IBBQ Invesco Nasdaq Biotechnology ETF 48.1% 254 $121m +42.7% \n 6 FBT First Trust NYSE Arca Biotechnology Inde 38.2% 30 $3.1bn +47.0% \n 7 BBP Virtus Biotech ETF 19.6% 67 $99m +44.4% \n 8 XBI State Street SPDR S&P Biotech ETF 18.1% 165 $10.6bn +47.9% \n 9 BBC Virtus Biotech Clinical Trials ETF 11.8% 131 $46m +45.9% \n \n Method\n The 9 of 10 ETFs in the biotech theme with a filed book, most concentrated first. Across the funds listed here the weight in the ten largest runs from 11.8% to 73.5%. Concentration is not a fault. It shows how much rides on ten holdings. The list sorts one published number, with no scoring or weighting. Every fund ETFIQ covers in this category is eligible, closed funds included.\n Where to next\n Every biotech ETF and what it holds The largest biotech ETFs Sources\n Fund holdings from SEC Form N-PORT and from the issuers\u2019 own daily files SEC EDGAR, full-text search of fund filings SEC Form N-PORT, what a fund filed it holds Rule 19a-1, what a distribution notice must say Links are sources, not endorsements.\n A ranking is not a recommendation or an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources \n Cite this page. ETFIQ, The most concentrated biotech ETFs, ranked by the share of the fund held in its ten largest positions, data as of Nov 4, 2026. https://etfiq.com/rankings/themes-concentrated-biotech Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data .\n Other forms Plain ETFIQ, The most concentrated biotech ETFs, ranked by the share of the fund held in its ten largest positions, data as of Nov 4, 2026. https://etfiq.com/rankings/themes-concentrated-biotech APA ETFIQ. (Nov 4, 2026). The most concentrated biotech ETFs, ranked by the share of the fund held in its ten largest positions. Retrieved from https://etfiq.com/rankings/themes-concentrated-biotech Markdown [The most concentrated biotech ETFs, ranked by the share of the fund held in its ten largest positions (ETFIQ, Nov 4, 2026)](https://etfiq.com/rankings/themes-concentrated-biotech)","source":"ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.","publisher":{"@id":"https://etfiq.com/#org","name":"ETFIQ","url":"https://etfiq.com"},"license":"https://etfiq.com/license/","license_text":"Data ETFIQ computes is free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.","citation":"ETFIQ, The most concentrated biotech ETFs, ranked by the share of the fund held in its ten largest positions, data as of Nov 4, 2026. https://etfiq.com/rankings/themes-concentrated-biotech"}