# The cheapest healthcare innovation ETFs

> The cheapest healthcare innovation ETFs, ranked by the annual fee the fund charges, as of Oct 20, 2026. 8 funds from ETFIQ’s own published figures.

Data as of Oct 20, 2026. Rebuilt every trading night.

As of Oct 20, 2026 . Rebuilt every trading night.

## The cheapest healthcare innovation ETFs

See 8 funds ranked by the annual fee the fund charges. Updated Oct 20, 2026. A fee is one fact, not a verdict. Funds on one theme can hold different companies, and the holdings are on the theme page.

| # | Ticker | Fund | Fee | Net assets | Weight in S&P 500 companies | Total return, 1Y |
| --- | --- | --- | --- | --- | --- | --- |
| 1 | WDNA | WisdomTree BioRevolution Fund | 0.45% | $3m | 25.9% | +36.0% |
| 2 | HEAL | Global X HealthTech ETF | 0.50% | $31m | 28.8% | −6.1% |
| 3 | HELX | Franklin Genomic Advancements ETF | 0.50% | $34m | 14.9% | +25.1% |
| 4 | BMED | iShares Health Innovation Active ETF | 0.55% | $14m | 58.4% | +25.4% |
| 5 | OZEM | Roundhill GLP-1 & Weight Loss ETF | 0.59% | $56m | 29.3% | +8.8% |
| 6 | THNR | Amplify Weight Loss Drug & Treatment ETF | 0.59% | $6m | 44.8% | +7.8% |
| 7 | EKG | First Trust Nasdaq Lux Digital Health So | 0.65% | $10m | 41.4% | +31.2% |
| 8 | LGHT | Langar Global HealthTech ETF | 0.85% | $2m | 57.9% | +10.1% |

### Method

The 8 of 8 ETFs in the healthcare innovation and glp-1 theme that publish an expense ratio, cheapest first. Across the funds listed here the annual fee runs from 0.5% to 0.8%. A fee is the one number a fund controls and the one a holder always pays. The list sorts one published figure, with no scoring or weighting. Every fund ETFIQ covers in this category is eligible, closed funds included.

### Where to next

### Where these figures came from

ETFIQ links to the documents behind every figure; a link is not an endorsement.

A ranking is not a recommendation or an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources

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Source: ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.
Cite: ETFIQ, The cheapest healthcare innovation ETFs, ranked by the annual fee the fund charges, data as of Oct 20, 2026. https://etfiq.com/rankings/themes-cheapest-health-innovation
Licence: https://etfiq.com/license/ Figures ETFIQ computes are free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.
HTML: https://etfiq.com/rankings/themes-cheapest-health-innovation