# XBI Leveraged ETFs: 2x, 3x & Inverse, Compared

> 3 leveraged and inverse ETFs on XBI: multiple, issuer, fee and net assets. Each against its stated multiple, as of Oct 27, 2026.

Data as of Oct 27, 2026. Rebuilt every trading night.

Data as of Oct 27, 2026 .

## XBI leveraged and inverse ETFs

As of Oct 27, 2026, 3 ETFs aim to return −3x to 3x the daily move in biotech (XBI). 2 issuers sell them. Over three months they finished from −10.1 to −5.9 percentage points against what their stated multiples implied.

### Browse leveraged ETFs

### All 3 leveraged and inverse ETFs on XBI

| Ticker | Fund | Issuer | 1M vs multiple | 3M vs multiple | 1Y vs multiple | Net assets | Net assets as of | Fee | Total return 1M | Total return 3M | Total return YTD | Total return 1Y | Total return 3Y | Total return since launch | Multiple |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| LABU | Direxion Daily S&P Biotech Bull 3X ETF | Direxion | −3.7 pts | −10.1 pts | −26.7 pts | $586m | Oct 26, 2026 | 0.96% | −4.0% | +0.1% | +52.0% | +91.2% | +396.4% | −92.1% | +3x |
| LABD | Direxion Daily S&P Biotech Bear 3X ETF | Direxion | −4.1 pts | −8.8 pts | not comparable | $66m | Oct 26, 2026 | 1.07% | −3.8% | −19.0% | −65.3% | −74.4% | −97.3% | −100.0% | -3x |
| XBIX | Corgi U.S. Biotech 2x Daily ETF | Corgi | −2.3 pts | −5.9 pts | not available | $338,071 | Oct 27, 2026 | 0.45% | −2.5% | +0.9% | not available | not available | not available | +30.9% since Jun 2026 | +2x |

What XBI itself did over the same days: −0.1% over one month, +3.4% over three months, +39.3% over one year.

### Questions people ask

Which 3x XBI ETFs are there? As of Oct 27, 2026, 1 ETF sets out to return 3x the daily move in biotech ( XBI ): LABU. Which 2x XBI ETFs are there? As of Oct 27, 2026, 1 ETF sets out to return 2x the daily move in biotech ( XBI ): XBIX. Which inverse XBI ETFs are there? As of Oct 27, 2026, 1 ETF sets out to return the opposite of the daily move in biotech ( XBI ), at −3x: LABD. Which XBI leveraged ETF is largest? LABU , Direxion Daily S&P Biotech Bull 3X ETF, at $586m in net assets on Oct 26, 2026, the largest of the 3 on XBI with a published size.

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Source: ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.
Cite: ETFIQ, XBI leveraged and inverse ETFs, data as of Oct 27, 2026. https://etfiq.com/leverage/xbi-leveraged-etfs
Licence: https://etfiq.com/license/ Data ETFIQ computes is free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.
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