# ETFs that hold Ligand Pharmaceuticals Inc

> 85 US listed ETFs hold Ligand Pharmaceuticals Inc, most of all HELX at 4.68% of the fund. Weights and filing dates for every holder.

Data as of Oct 4, 2026. Rebuilt every trading night.

## ETFs that hold Ligand Pharmaceuticals Inc

85 US listed ETFs hold Ligand Pharmaceuticals Inc. HELX holds the most, at 4.68% of the fund.

### Every fund that holds it

| Fund | Name | Share of the fund | Holdings filed |
| --- | --- | --- | --- |
| HELX | Franklin Genomic Advancements ETF | 4.68% | Jun 30, 2026 |
| PJP | Invesco Pharmaceuticals ETF | 3.52% | Oct 3, 2026 |
| PSCH | Invesco S&P SmallCap Health Care ETF | 3.28% | Oct 3, 2026 |
| CSMD | Congress SMid Growth ETF | 2.66% | Jul 31, 2026 |
| AFSC | abrdn Focused U.S. Small Cap Active ETF | 2.23% | Jul 31, 2026 |
| ALIL | Argent Focused Small Cap ETF | 2.16% | May 29, 2026 |
| XPH | State Street SPDR S&P Pharmaceuticals ETF | 2.13% | Oct 1, 2026 |
| XSMO | Invesco S&P SmallCap Momentum ETF | 1.91% | Oct 3, 2026 |
| BBP | Virtus Biotech ETF | 1.55% | Jul 31, 2026 |
| IHE | iShares U.S. Pharmaceuticals ETF | 1.37% | Oct 1, 2026 |
| RZG | Invesco S&P SmallCap 600 Pure Growth ETF | 1.28% | Oct 3, 2026 |
| SGRW | Harbor Active Small Cap Growth ETF | 1.21% | Jul 31, 2026 |
| MMSC | First Trust Multi-Manager Small Cap Opportunities ETF | 1.07% | Oct 2, 2026 |
| GSC | Goldman Sachs Small Cap Equity ETF | 1.04% | May 31, 2026 |
| FPX | First Trust US Equity Opportunities ETF | 0.99% | Oct 2, 2026 |
| CAFG | Pacer US Small Cap Cash Cows Growth Leaders ETF | 0.96% | Jul 31, 2026 |
| SLYG | State Street SPDR S & P 600 Small Cap Growth ETF | 0.74% | Oct 1, 2026 |
| IJT | iShares S&P Small-Cap 600 Growth ETF | 0.73% | Oct 1, 2026 |
| RUSC | Russell Investments U.S. Small Cap Equity ETF | 0.70% | Jun 30, 2026 |
| FYC | First Trust Small Cap Growth AlphaDEX Fund | 0.67% | Oct 2, 2026 |
| VIOG | Vanguard S&P Small-Cap 600 Growth ETF | 0.65% | Aug 31, 2026 |
| JSML | Janus Henderson Small Cap Growth Alpha ETF | 0.62% | Jul 31, 2026 |
| QSML | WisdomTree U.S. SmallCap Quality Growth Fund | 0.61% | Jun 30, 2026 |
| FTXH | First Trust Nasdaq Pharmaceuticals ETF | 0.54% | Oct 2, 2026 |
| DWAS | Invesco Dorsey Wright SmallCap Momentum ETF | 0.46% | Oct 3, 2026 |
| SAWS | AAM SAWGRASS U.S. SMALL CAP QUALITY GROWTH ETF | 0.41% | Jul 31, 2026 |
| IBBQ | Invesco Nasdaq Biotechnology ETF | 0.41% | Oct 3, 2026 |
| IWO | iShares Russell 2000 Growth ETF | 0.40% | Oct 1, 2026 |
| XJR | iShares ESG Select Screened S&P Small-Cap ETF | 0.38% | Oct 1, 2026 |
| QVMS | Invesco S&P SmallCap 600 QVM Multi-factor ETF | 0.38% | Oct 3, 2026 |
| VTWG | Vanguard Russell 2000 Growth ETF | 0.35% | Aug 31, 2026 |
| JPSE | JPMorgan Diversified Return U.S. Small Cap Equity ETF | 0.35% | Jul 31, 2026 |
| SPSM | State Street SPDR Portfolio S&P 600 Small Cap ETF | 0.35% | Oct 1, 2026 |
| IJR | iShares Core S&P Small-Cap ETF | 0.35% | Oct 1, 2026 |
| FYX | First Trust Small Cap Core AlphaDEX Fund | 0.32% | Oct 2, 2026 |
| VIOO | Vanguard S&P Small-Cap 600 ETF | 0.32% | Aug 31, 2026 |
| BFOR | Barron's 400 ETF | 0.26% | May 31, 2026 |
| BKSE | BNY Mellon US Small Cap Core Equity ETF | 0.25% | Jul 31, 2026 |
| STXK | Strive Small-Cap ETF | 0.25% | Jun 30, 2026 |
| BBSC | JPMorgan BetaBuilders U.S. Small Cap Equity ETF | 0.22% | Jul 31, 2026 |
| SMLF | iShares U.S. Small-Cap Equity Factor ETF | 0.21% | Oct 1, 2026 |
| RFLR | Innovator U.S. Small Cap Managed Floor ETF | 0.20% | Jul 31, 2026 |
| KBFR | Innovator U.S. Small Cap Managed 10 Buffer ETF | 0.20% | Jul 31, 2026 |
| IWM | iShares Russell 2000 ETF | 0.20% | Oct 1, 2026 |
| RSSL | Global X Russell 2000 ETF | 0.20% | Oct 2, 2026 |
| GSSC | GS ActiveBeta U.S. Small Cap Equity ETF | 0.19% | May 31, 2026 |
| JMEE | JPMorgan Small & Mid Cap Enhanced Equity ETF | 0.18% | Jun 30, 2026 |
| FSMD | Fidelity Small-Mid Multifactor ETF | 0.18% | Jul 31, 2026 |
| AFSM | First Trust Active Factor Small Cap ETF | 0.18% | Oct 2, 2026 |
| VTWO | Vanguard Russell 2000 ETF | 0.18% | Aug 31, 2026 |
| SMLV | State Street SPDR US Small Cap Low Volatility Index ETF | 0.16% | Oct 1, 2026 |
| SCHA | Schwab U.S. Small-Cap ETF | 0.15% | Oct 1, 2026 |
| ITWO | ProShares Russell 2000 High Income ETF | 0.13% | May 31, 2026 |
| FAD | First Trust Multi Cap Growth AlphaDEX Fund | 0.13% | Oct 2, 2026 |
| EZM | WisdomTree U.S. MidCap Fund | 0.12% | Jun 30, 2026 |
| ISCG | iShares Morningstar Small-Cap Growth ETF | 0.12% | Oct 1, 2026 |
| VBR | Vanguard Morningstar Small-Cap Value ETF | 0.12% | Aug 31, 2026 |
| SMMV | iShares MSCI USA Small-Cap Min Vol Factor ETF | 0.10% | Oct 1, 2026 |
| ISCB | iShares Morningstar Small-Cap ETF | 0.10% | Oct 1, 2026 |
| PRFZ | Invesco RAFI US 1500 Small-Mid ETF | 0.09% | Oct 3, 2026 |
| FHLC | Fidelity MSCI Health Care Index ETF | 0.08% | Jul 31, 2026 |
| VHT | Vanguard Health Care ETF | 0.08% | Aug 31, 2026 |
| ISCV | iShares Morningstar Small-Cap Value ETF | 0.07% | Oct 1, 2026 |
| VXF | Vanguard Extended Market ETF | 0.07% | Aug 31, 2026 |
| VB | Vanguard Morningstar Small-Cap ETF | 0.07% | Aug 31, 2026 |
| WSML | iShares MSCI World Small-Cap ETF | 0.06% | Oct 1, 2026 |
| AVIE | Avantis Inflation Focused Equity ETF | 0.05% | Oct 1, 2026 |
| VFMO | Vanguard U.S. Momentum Factor ETF | 0.05% | May 31, 2026 |
| OMFS | Invesco Russell 2000 Dynamic Multifactor ETF | 0.03% | Oct 3, 2026 |
| MSSM | Morgan Stanley Pathway Small-Mid Cap Equity ETF | 0.02% | May 31, 2026 |
| RWJ | Invesco S&P SmallCap 600 Revenue ETF | 0.02% | Oct 3, 2026 |
| MMTM | State Street SPDR S&P 1500 Momentum Tilt ETF | 0.02% | Oct 1, 2026 |
| GTPE | Goldman Sachs MSCI World Private Equity Return Tracker ETF | 0.01% | May 31, 2026 |
| ONEQ | Fidelity Nasdaq Composite Index ETF | 0.01% | May 31, 2026 |
| ITOT | iShares Core S&P Total U.S. Stock Market ETF | 0.01% | Oct 1, 2026 |
| IWV | iShares Russell 3000 ETF | 0.01% | Oct 1, 2026 |
| ESGV | Vanguard ESG U.S. Stock ETF | 0.01% | Aug 31, 2026 |
| SCHK | Schwab 1000 Index ETF | 0.01% | Oct 1, 2026 |
| SCHB | Schwab U.S. Broad Market ETF | 0.01% | Oct 1, 2026 |
| VTHR | Vanguard Russell 3000 ETF | 0.01% | Aug 31, 2026 |
| TILT | Northern Trust Morningstar US Market Factor Tilt ETF | 0.01% | Jul 31, 2026 |
| SPTM | State Street SPDR Portfolio S&P 1500 Composite Stock Market ETF | 0.01% | Oct 1, 2026 |
| VTI | Vanguard Morningstar Total Stock Market ETF | 0.01% | Aug 31, 2026 |
| VT | Vanguard Total World Stock Index ETF | 0.01% | Aug 31, 2026 |
| VLU | State Street SPDR S&P 1500 Value Tilt ETF | 0.00% | Oct 1, 2026 |

### What this counts

Ligand Pharmaceuticals Inc (ticker LGND, listed in US) is matched across every holdings book ETFIQ publishes, by its ticker together with its name. A share of the fund is the weight the issuer itself published, as of the date in the last column. Option contracts, swaps, futures, cash and money market holdings are not counted as holding a company: a fund holding a call option on a share does not hold the share. Funds whose published book is gross exposure rather than a portfolio are left out entirely, because a weight in such a book is not a share of anything.

Holdings change. Each row carries the date the fund last filed, and a fund that files quarterly can have traded since.

Look up another company .

Cite this page. ETFIQ, ETFs holding Ligand Pharmaceuticals Inc, data as of Oct 4, 2026. https://etfiq.com/holdings/lgnd/ Free to use with attribution ; the underlying files are at Open data .

Other forms Plain ETFIQ, ETFs holding Ligand Pharmaceuticals Inc, data as of Oct 4, 2026. https://etfiq.com/holdings/lgnd/ APA ETFIQ. (Oct 4, 2026). ETFs holding Ligand Pharmaceuticals Inc. Retrieved from https://etfiq.com/holdings/lgnd/ Markdown [ETFs holding Ligand Pharmaceuticals Inc (ETFIQ, Oct 4, 2026)](https://etfiq.com/holdings/lgnd/)

---

Source: ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.
Cite: ETFIQ, as of Oct 4, 2026. https://etfiq.com/holdings/lgnd
License: https://etfiq.com/standards/
HTML: https://etfiq.com/holdings/lgnd