# KRYS ETFs: 120 Funds That Hold Krystal Biotech Inc

> 120 thematic and core ETFs hold Krystal Biotech Inc (KRYS). HELX holds the most, at 6.33% of the fund on Jun 30, 2026. Weights and dates for every holder.

Data as of Nov 5, 2026. Rebuilt every trading night.

## ETFs that hold Krystal Biotech Inc

120 thematic and core ETFs hold Krystal Biotech Inc , by holdings dated Jun 30, 2026 to Nov 4, 2026 . HELX holds the most, at 6.33% of the fund on Jun 30, 2026 . The next largest are FFTY (2.06%) and WDNA (1.96%).

2 income and other funds on it are listed below.

### Thematic and core funds that hold it

| Fund | Name | Share of the fund | Holdings filed | Asset |
| --- | --- | --- | --- | --- |
| HELX | Franklin Genomic Advancements ETF | 6.33% | Jun 30, 2026 | Equity |
| FFTY | CapForce IBD 50 ETF | 2.06% | Jul 31, 2026 | Equity |
| WDNA | WisdomTree BioRevolution Fund | 1.96% | Jun 30, 2026 | Equity |
| SAWS | AAM SAWGRASS U.S. SMALL CAP QUALITY GROWTH ETF | 1.89% | Jul 31, 2026 | Equity |
| GNMX | Corgi Genomics & Precision Medicine ETF | 1.63% | Nov 4, 2026 | Equity |
| CAFG | Pacer US Small Cap Cash Cows Growth Leaders ETF | 1.48% | Jul 31, 2026 | Equity |
| BBP | Virtus Biotech ETF | 1.48% | Jul 31, 2026 | Equity |
| RFG | Invesco S&P MidCap 400 Pure Growth ETF | 1.29% | Nov 3, 2026 | Equity |
| XBI | State Street SPDR S&P Biotech ETF | 1.28% | Nov 3, 2026 | Equity |
| GURU | Global X Guru Index ETF | 1.27% | Jul 31, 2026 | Equity |
| XMMO | Invesco S&P MidCap Momentum ETF | 1.25% | Nov 3, 2026 | Equity |
| GSC | Goldman Sachs Small Cap Equity ETF | 1.21% | Aug 31, 2026 | Equity |
| JSML | Janus Henderson Small Cap Growth Alpha ETF | 1.20% | Jul 31, 2026 | Equity |
| CSMD | Congress SMid Growth ETF | 1.14% | Jul 31, 2026 | Equity |
| ACSG | American Century Small Cap Growth Insights ETF | 1.10% | Aug 31, 2026 | Equity |
| JSMD | Janus Henderson Small/Mid Cap Growth Alpha ETF | 0.93% | Jul 31, 2026 | Equity |
| OMFS | Invesco Russell 2000 Dynamic Multifactor ETF | 0.93% | Nov 3, 2026 | Equity |
| QMID | WisdomTree U.S. MidCap Quality Growth Fund | 0.88% | Jun 30, 2026 | Equity |
| SSMG | VIRTUS SILVANT SMALL/MID GROWTH ETF | 0.85% | Jul 31, 2026 | Equity |
| IBBQ | Invesco Nasdaq Biotechnology ETF | 0.58% | Nov 3, 2026 | Equity |
| VTWG | Vanguard Russell 2000 Growth ETF | 0.57% | Sep 30, 2026 | Equity |
| AFSM | First Trust Active Factor Small Cap ETF | 0.56% | Nov 3, 2026 | Equity |
| JHSC | John Hancock Multifactor Small Cap ETF | 0.55% | Jun 30, 2026 | Equity |
| IBB | iShares Biotechnology ETF | 0.54% | Nov 3, 2026 | Equity |
| IWO | iShares Russell 2000 Growth ETF | 0.54% | Nov 3, 2026 | Equity |
| FSEG | Fidelity Enhanced Small Cap Growth ETF | 0.52% | Jun 30, 2026 | Equity |
| IVOG | Vanguard S&P Mid-Cap 400 Growth ETF | 0.49% | Sep 30, 2026 | Equity |
| FLDZ | TrueShares Patriot Defense ETF | 0.48% | Jun 30, 2026 | Equity |
| IJK | iShares S&P Mid-Cap 400 Growth ETF | 0.47% | Nov 3, 2026 | Equity |
| MDYG | State Street SPDR S & P 400 Mid Cap Growth ETF | 0.47% | Nov 3, 2026 | Equity |
| USMF | WisdomTree U.S. Multifactor Fund | 0.46% | Jun 30, 2026 | Equity |
| TMFX | Motley Fool Next Index ETF | 0.45% | Aug 31, 2026 | Equity |
| FNY | First Trust Mid Cap Growth AlphaDEX Fund | 0.41% | Nov 3, 2026 | Equity |
| PSC | Principal U.S. Small-Cap ETF | 0.40% | Jun 30, 2026 | Equity |
| FTXH | First Trust Nasdaq Pharmaceuticals ETF | 0.40% | Nov 3, 2026 | Equity |
| USVM | VictoryShares US Small Mid Cap Value Momentum ETF | 0.39% | Jun 30, 2026 | Equity |
| DWAS | Invesco Dorsey Wright SmallCap Momentum ETF | 0.36% | Nov 3, 2026 | Equity |
| SMMV | iShares MSCI USA Small-Cap Min Vol Factor ETF | 0.34% | Nov 3, 2026 | Equity |
| IQSM | NYLIM Candriam U.S. Mid Cap Equity ETF | 0.33% | Jul 31, 2026 | Equity |
| BBSC | JPMorgan BetaBuilders U.S. Small Cap Equity ETF | 0.32% | Nov 3, 2026 | Equity |
| MFMO | Motley Fool Momentum Factor ETF | 0.32% | Aug 31, 2026 | Equity |
| BFOR | Barron's 400 ETF | 0.32% | Aug 31, 2026 | Equity |
| RESM | Columbia Research Enhanced Small Cap ETF | 0.30% | Jun 30, 2026 | Equity |
| MFIG | Motley Fool Innovative Growth Factor ETF | 0.30% | Aug 31, 2026 | Equity |
| RSSL | Global X Russell 2000 ETF | 0.29% | Jul 31, 2026 | Equity |
| VTWO | Vanguard Russell 2000 ETF | 0.29% | Sep 30, 2026 | Equity |
| SEIS | SEI Select Small Cap ETF | 0.28% | Jun 30, 2026 | Equity |
| TNXT | T. Rowe Price Innovation Leaders ETF | 0.28% | Jun 30, 2026 | Equity |
| MSSM | Morgan Stanley Pathway Small-Mid Cap Equity ETF | 0.28% | Aug 31, 2026 | Equity |
| IWM | iShares Russell 2000 ETF | 0.27% | Nov 3, 2026 | Equity |
| SQLT | iShares MSCI USA Small-Cap Quality Factor ETF | 0.27% | Nov 3, 2026 | Equity |
| XJH | iShares ESG Select Screened S&P Mid-Cap ETF | 0.27% | Nov 3, 2026 | Equity |
| QVMM | Invesco S&P MidCap 400 QVM Multi-factor ETF | 0.26% | Nov 3, 2026 | Equity |
| TPSC | Timothy Plan US Small Cap Core ETF | 0.26% | Jun 30, 2026 | Equity |
| ISCG | iShares Morningstar Small-Cap Growth ETF | 0.26% | Nov 3, 2026 | Equity |
| IVOO | Vanguard S&P Mid-Cap 400 ETF | 0.26% | Sep 30, 2026 | Equity |
| RUSC | Russell Investments U.S. Small Cap Equity ETF | 0.26% | Jun 30, 2026 | Equity |
| VBK | Vanguard Morningstar Small-Cap Growth ETF | 0.25% | Sep 30, 2026 | Equity |
| VFMO | Vanguard U.S. Momentum Factor ETF | 0.25% | Sep 30, 2026 | Equity |
| SMOX | HORIZON SMALL/MID CAP CORE EQUITY ETF | 0.25% | Aug 31, 2026 | Equity |
| IJH | iShares Core S&P Mid-Cap ETF | 0.24% | Nov 3, 2026 | Equity |
| SPMD | State Street SPDR Portfolio S&P 400 Mid Cap ETF | 0.24% | Nov 3, 2026 | Equity |
| MDY | SPDR S&P MidCap 400 ETF Trust | 0.23% | Nov 3, 2026 | Equity |
| JPSE | JPMorgan Diversified Return U.S. Small Cap Equity ETF | 0.23% | Nov 3, 2026 | Equity |
| DFAS | U.S. Small Cap Portfolio: ETF Class Shares | 0.23% | Jul 31, 2026 | Equity |
| FSCC | Federated Hermes MDT Small Cap Core ETF | 0.23% | Aug 31, 2026 | Equity |
| BKMC | BNY Mellon US Mid Cap Core Equity ETF | 0.21% | Jul 31, 2026 | Equity |
| FSMD | Fidelity Small-Mid Multifactor ETF | 0.21% | Jul 31, 2026 | Equity |
| PWS | Pacer WealthShield ETF | 0.21% | Jul 31, 2026 | Equity |
| FFF | Founders 100 ETF | 0.21% | Jun 30, 2026 | Equity |
| GSSC | GS ActiveBeta U.S. Small Cap Equity ETF | 0.20% | Aug 31, 2026 | Equity |
| SXQG | ETC 6 Meridian Quality Growth ETF | 0.20% | Aug 31, 2026 | Equity |
| SCHA | Schwab U.S. Small-Cap ETF | 0.20% | Aug 31, 2026 | Equity |
| FNX | First Trust Mid Cap Core AlphaDEX Fund | 0.19% | Nov 3, 2026 | Equity |
| PTMC | Pacer Trendpilot US Mid Cap ETF | 0.17% | Jul 31, 2026 | Equity |
| SMDX | Intech S&P Small-Mid Cap Diversified Alpha ETF | 0.17% | Jul 31, 2026 | Equity |
| EZM | WisdomTree U.S. MidCap Fund | 0.16% | Jun 30, 2026 | Equity |
| ISCB | | 0.14% | Jul 31, 2026 | Equity |
| FAD | First Trust Multi Cap Growth AlphaDEX Fund | 0.13% | Nov 3, 2026 | Equity |
| FSML | FRANKLIN SMALL CAP ENHANCED ETF | 0.12% | Jun 30, 2026 | Equity |
| VB | Vanguard Morningstar Small-Cap ETF | 0.11% | Sep 30, 2026 | Equity |
| VXF | Vanguard Extended Market ETF | 0.11% | Sep 30, 2026 | Equity |
| FHLC | Fidelity MSCI Health Care Index ETF | 0.10% | Jul 31, 2026 | Equity |
| CVMC | Calvert US Mid-Cap Core Responsible Index ETF | 0.10% | Jun 30, 2026 | Equity |
| MSML | iShares MSCI USA Small-Cap ETF | 0.10% | Nov 3, 2026 | Equity |
| VHT | Vanguard Health Care ETF | 0.10% | Sep 30, 2026 | Equity |
| JMEE | JPMorgan Small & Mid Cap Enhanced Equity ETF | 0.09% | Nov 3, 2026 | Equity |
| KOMP | State Street SPDR S&P Kensho New Economies Composite ETF | 0.08% | Nov 3, 2026 | Equity |
| AVMC | Avantis U.S. Mid Cap Equity ETF | 0.08% | Nov 2, 2026 | Equity |
| GTPE | Goldman Sachs MSCI World Private Equity Return Tracker ETF | 0.08% | Aug 31, 2026 | Equity |
| JHMM | John Hancock Multifactor Mid Cap ETF | 0.08% | Jun 30, 2026 | Equity |
| ESML | iShares ESG Aware MSCI USA Small-Cap ETF | 0.07% | Nov 3, 2026 | Equity |
| WSML | iShares MSCI World Small-Cap ETF | 0.06% | Nov 3, 2026 | Equity |
| AVIE | Avantis Inflation Focused Equity ETF | 0.05% | Nov 2, 2026 | Equity |
| PRFZ | Invesco RAFI US 1500 Small-Mid ETF | 0.05% | Nov 3, 2026 | Equity |
| FESM | Fidelity Enhanced Small Cap Core ETF | 0.04% | Jun 30, 2026 | Equity |
| DFAC | U.S. Core Equity 2 Portfolio ETF Class Shares | 0.03% | Jul 31, 2026 | Equity |
| ONEQ | Fidelity Nasdaq Composite Index ETF | 0.02% | Aug 31, 2026 | Equity |
| DCOR | US Core Equity 1 Portfolio ETF Class Shares | 0.02% | Jul 31, 2026 | Equity |
| AVLC | Avantis U.S. Large Cap Equity ETF | 0.02% | Nov 2, 2026 | Equity |
| IUSG | iShares Core S&P U.S. Growth ETF | 0.02% | Nov 3, 2026 | Equity |
| TILT | Northern Trust Morningstar US Market Factor Tilt ETF | 0.02% | Jul 31, 2026 | Equity |
| MMTM | State Street SPDR S&P 1500 Momentum Tilt ETF | 0.02% | Nov 3, 2026 | Equity |
| CVLC | Calvert US Large-Cap Core Responsible Index ETF | 0.02% | Jun 30, 2026 | Equity |
| RWK | Invesco S&P MidCap 400 Revenue ETF | 0.02% | Nov 3, 2026 | Equity |
| DFAU | Dimensional US Core Equity Market ETF | 0.01% | Jul 31, 2026 | Equity |
| ESGV | Vanguard ESG U.S. Stock ETF | 0.01% | Sep 30, 2026 | Equity |
| SCHB | Schwab U.S. Broad Market ETF | 0.01% | Aug 31, 2026 | Equity |
| DFSU | Dimensional US Sustainability Core 1 ETF | 0.01% | Jul 31, 2026 | Equity |
| GUSA | Goldman Sachs MarketBeta U.S. 1000 Equity ETF | 0.01% | Aug 31, 2026 | Equity |
| SPTM | State Street SPDR Portfolio S&P 1500 Composite Stock Market ETF | 0.01% | Nov 3, 2026 | Equity |
| VTI | Vanguard Morningstar Total Stock Market ETF | 0.01% | Sep 30, 2026 | Equity |
| VTHR | Vanguard Russell 3000 ETF | 0.01% | Sep 30, 2026 | Equity |
| AVUS | Avantis U.S. Equity ETF | 0.01% | Nov 3, 2026 | Equity |
| DFUS | Dimensional U.S. Equity Market ETF | 0.01% | Jul 31, 2026 | Equity |
| ITOT | iShares Core S&P Total U.S. Stock Market ETF | 0.01% | Nov 3, 2026 | Equity |
| IWV | iShares Russell 3000 ETF | 0.01% | Nov 3, 2026 | Equity |
| VLU | State Street SPDR S&P 1500 Value Tilt ETF | 0.01% | Nov 3, 2026 | Equity |
| VT | Vanguard Total World Stock Index ETF | 0.01% | Sep 30, 2026 | Equity |
| EBI | Longview Advantage ETF | Krystal Biotech Inc (ticker KRYS, listed in US) is matched in every holdings book ETFIQ publishes, by its ticker and name. A share of the fund is the weight its issuer published, as of the Holdings filed date. Shares, preferred shares and debt are told by each fund’s N-PORT asset type. A fund holding only the company’s debt or preferred shares is listed under them, not counted as holding its shares. Options, swaps, futures and cash do not count as holding a company: a call option on a share is not the share. Funds whose book is gross exposure, not a portfolio, are left out.

Each row shows the date the fund last filed.

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### Questions people ask

Which ETFs hold Krystal Biotech Inc? 120 thematic and core ETFs hold Krystal Biotech Inc, by holdings dated Jun 30, 2026 to Nov 4, 2026. The largest positions are HELX at 6.33% of the fund on Jun 30, 2026, FFTY at 2.06% of the fund on Jul 31, 2026 and WDNA at 1.96% of the fund on Jun 30, 2026. 2 income and other funds on it are listed apart.

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Source: ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.
Cite: ETFIQ, ETFs holding Krystal Biotech Inc, data as of Nov 5, 2026. https://etfiq.com/holdings/krys/
Licence: https://etfiq.com/license/ Data ETFIQ computes is free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.
HTML: https://etfiq.com/holdings/krys/