# XBI (State Street SPDR S&P Biotech ETF) State Street · Thematic ETFs · data as of Oct 28, 2026 Promise check: Not measured. Its theme exposure is measured once ETFIQ defines its theme company by company. https://etfiq.com/promise-index/ Over the year to Oct 28, 2026, XBI returned 41.2%. ## Key facts - XBI, already in the S&P 500: 13.2%, as of Oct 27, 2026. - XBI, active share vs the S&P 500: 98.4%, as of Oct 27, 2026. - XBI, top ten holdings: 17.8%, as of Oct 27, 2026. - XBI, total return, 1 year: +41.2%, as of Oct 28, 2026. - XBI, 12-month yield, capital gains included, on its starting price: 0.5%, as of Oct 28, 2026. - XBI, last payment (paid quarterly), ex-date Jun 22, 2026: $0.1381, as of Jun 22, 2026. - XBI, net assets: $10.3bn (the issuer’s own daily fund list, as of Oct 27, 2026). - XBI, expense ratio: 0.35% (485BPOS XBRL, Oct 24, 2025). ## XBI over each window to Oct 28, 2026 | Window | Total return | S&P 500 (SPY) | | --- | --- | --- | | 1 month | +0.6% | +0.9% | | 3 months | +6.5% | +6.1% | | 6 months | +22.3% | +9.1% | | Year to date | +29.3% | +14.1% | | 1 year | +41.2% | +13.6% | | 3 years | +147.2% | +95.0% | | 5 years | +27.0% | +79.8% | | 10 years | +181.0% | +325.8% | | Since launch | +914.8% | +791.2% | | Since launch, annualised | +11.8% | – | ## XBI key stats - 52-week high, daily closes to Oct 28, 2026: $169.55 on Aug 19, 2026 (computed by ETFIQ from Tiingo daily prices) - 52-week low, daily closes to Oct 28, 2026: $108.04 on Nov 4, 2025 (computed by ETFIQ from Tiingo daily prices) - Close on Oct 28, 2026, within that range: $157.51, 80% of the way from the low to the high (computed by ETFIQ from Tiingo daily prices) - Holdings: 165 - Top ten holdings weight: 17.8% ## XBI trading - Not scored. - Premium to NAV at the Oct 27 close: +0.04%; 95% of days within ±0.06%. - The full trading page: https://etfiq.com/funds/xbi/trading/ ## Every published field | Field | Value | Source | | --- | --- | --- | | Theme | Biotech | ETFIQ, editorial | | First traded | Feb 6, 2006 | ETFIQ | | Already in the S&P 500, by weight | 13.2% | ETFIQ | | Outside the S&P 500, by weight | 87% | ETFIQ | | Active share vs the S&P 500 | 98.4% | ETFIQ | | Already in the Nasdaq-100, by weight | 8.6% | ETFIQ | | Active share vs the Nasdaq-100 | 97.4% | ETFIQ | | Top ten holdings weight | 17.8% | ETFIQ | | Holdings | 165 | ETFIQ | | Holdings published for | Oct 27, 2026 | the issuer’s daily file | | Holdings as of the close of | Oct 27, 2026 | the issuer’s daily file | | Top holdings | MODERNA INC 2.2%, TWIST BIOSCIENCE CORP 1.9%, NATERA INC 1.8%, BIOGEN INC 1.8%, HALOZYME THERAPEUTICS INC 1.8%, UNITED THERAPEUTICS CORP 1.7%, AMGEN INC 1.7%, ABBVIE INC 1.7%, SPYRE THERAPEUTICS INC 1.7%, EXELIXIS INC 1.6% | ETFIQ | | Net assets | $10.3bn | the issuer’s own daily fund list, as of Oct 27, 2026 | | Benchmark | Its own holdings, as of Oct 27, 2026; its shareholder report compares it with the S&P 500 Index, but its daily returns fit IVV's at R-squared 0.22 over the year to Oct 28, 2026 (251 days), under the 0.35 it needs to return to it | ETFIQ, from its filings | | Below its all-time high | −8.9% | ETFIQ | | Expense ratio | 0.35% | 485BPOS XBRL, Oct 24, 2025 | | Fee for the part that differs from the S&P 500, active expense ratio | 0.36% | ETFIQ | | Closest funds by holdings overlap | BBP 46%, IBBQ 43%, IBB 43%, WDNA 36%, BBC 31% | ETFIQ | ## Money in and out, to Oct 22, 2026 | Window | Dates | Net flow | | --- | --- | --- | | 1 week | Oct 21, 2026 to Oct 22, 2026 | +$234m | | 1 month | Sep 28, 2026 to Oct 22, 2026 | +$576m | | 3 months | Jul 28, 2026 to Oct 22, 2026 | +$623m | | Year to date | Jan 2, 2026 to Oct 22, 2026 | +$894m | | 1 year | Oct 28, 2025 to Oct 22, 2026 | +$1.4bn (of which a round trip: −$73.1m) | Computed by ETFIQ from the change in shares outstanding times the previous day’s NAV. Every day and month: . Method: https://etfiq.com/methodology/flows ## Questions ### How much of XBI is in S&P 500 companies? By its holdings published by its issuer for Oct 27, 2026, 13% of XBI by weight is stocks the S&P 500 already holds. Its active share against the index is 98%, so that share is the part doing something different. ### What does XBI hold? 165 positions as published by its issuer for Oct 27, 2026, with the top ten at 18% of the fund. The largest are MODERNA INC at 2.2%, TWIST BIOSCIENCE CORP at 1.9%, NATERA INC at 1.8%. ### Has XBI beaten the S&P 500? Over the year to Oct 28, 2026 XBI returned +41.2% with distributions reinvested, against +13.6% for the S&P 500, so it finished ahead of the index by 27.6 points. ### What does XBI cost? The prospectus expense ratio is 0.35% a year. Because 98% of the fund differs from the S&P 500, the fee on that differing part works out at 0.36%. ## Cite this page ETFIQ, XBI, thematic ETFs, data as of Oct 28, 2026. https://etfiq.com/funds/xbi Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at . HTML: https://etfiq.com/funds/xbi · JSON: https://etfiq.com/funds/xbi.json