# IDNA (iShares Genomics Immunology and Healthcare ETF)

iShares · Thematic ETFs · data as of Sep 11, 2026

IDNA holds 53 stocks, and 76% of its weight is outside the S&P 500.

## Key facts

- IDNA, already in the S&P 500: 23.8%, as of Sep 11, 2026.
- IDNA, active share vs the S&P 500: 99.1%, as of Sep 11, 2026.
- IDNA, top ten holdings: 45.6%, as of Sep 11, 2026.
- IDNA, total return, 1 year: +65.8%, as of Sep 11, 2026.
- IDNA, net assets: $256m (the issuer own daily fund list, as of Sep 11, 2026).
- IDNA, expense ratio: 0.47% (485BPOS XBRL, Nov 21, 2025).

## IDNA over each window to Sep 11, 2026

| Window | Total return | S&P 500 | Gap to S&P 500 | Gap to Nasdaq-100 |
| --- | --- | --- | --- | --- |
| 3 months | +28.4% | +3.3% | +25.1 pts | +29.2 pts |
| 6 months | +32.8% | +16.0% | +16.8 pts | +12.1 pts |
| 1 year | +65.8% | +17.5% | +48.3 pts | +42.8 pts |
| 3 years | +77.3% | +77.9% | −0.6 pts | −17.8 pts |
| Since launch | +62.2% | +193.9% | −131.7 pts | −245.8 pts |

## Every published field

| Field | Value | Source |
| --- | --- | --- |
| Theme | Biotech and genomics | ETFIQ, editorial |
| Launched | Jun 13, 2019 | ETFIQ |
| Already in the S&P 500, by weight | 23.8% | ETFIQ |
| Active share vs the S&P 500 | 99.1% | ETFIQ |
| Already in the Nasdaq-100, by weight | 7.4% | ETFIQ |
| Active share vs the Nasdaq-100 | 99.2% | ETFIQ |
| Top ten holdings weight | 45.6% | ETFIQ |
| Holdings | 53 | ETFIQ |
| Holdings as of | Sep 10, 2026 | the issuer’s daily file |
| Top holdings | MODERNA 8.9%, TWIST BIOSCIENCE 5.7%, REVOLUTION MEDICINES 4.2%, BAYER AG 4.2%, GENMAB 4.1%, REGENERON PHARMACEUTICALS 3.9%, INCYTE CORP 3.7%, MERCK & CO INC 3.7%, TAKEDA PHARMACEUTICAL 3.7%, VERTEX PHARMACEUTICALS 3.6% | ETFIQ |
| Net assets | $256m | the issuer own daily fund list, as of Sep 11, 2026 |
| Below its all-time high | −28.0% | ETFIQ |
| Expense ratio | 0.47% | 485BPOS XBRL, Nov 21, 2025 |
| Fee for the part that differs from the S&P 500, active expense ratio | 0.47% | ETFIQ |
| Closest funds by holdings overlap | GNOM 26%, IBBQ 22%, BBH 22%, WDNA 21%, FBT 21% | ETFIQ |

## Questions

### How much of IDNA is in S&P 500 companies?

By its holdings published by its issuer for Sep 10, 2026, 24% of IDNA by weight is stocks the S&P 500 already holds. Its active share against the index is 99%, so that share is the part doing something different.

### What does IDNA hold?

53 positions as published by its issuer for Sep 10, 2026, with the top ten at 46% of the fund. The largest are MODERNA at 8.9%, TWIST BIOSCIENCE at 5.7%, REVOLUTION MEDICINES at 4.2%.

### Has IDNA beaten the S&P 500?

Over the year to Sep 11, 2026 IDNA returned +65.8% with distributions reinvested, against +17.5% for the S&P 500, so it finished ahead of the index by 48.3 points.

### What does IDNA cost?

The prospectus expense ratio is 0.47% a year. Because 99% of the fund differs from the S&P 500, the fee on that differing part works out at 0.47%.


## Cite this page

ETFIQ, IDNA, data as of Sep 11, 2026. https://etfiq.com/funds/idna
Free to use with attribution; the underlying files are at https://etfiq.com/data/.

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