# PBPH (Portfolio Building Block World Pharma and Biotech Index ETF)

not established · Thematic ETFs · data as of Sep 11, 2026

PBPH holds 51 stocks, and 43% of its weight is outside the S&P 500.

## Key facts

- PBPH, already in the S&P 500: 56.8%, as of Sep 11, 2026.
- PBPH, active share vs the S&P 500: 95.0%, as of Sep 11, 2026.
- PBPH, top ten holdings: 62.7%, as of Sep 11, 2026.
- PBPH, total return, since launch: +11.0%, as of Sep 11, 2026.
- PBPH, net assets: $36m (SEC filing, whole fund, as filed for Jan 31, 2026).
- PBPH, expense ratio: 0.13% (485BPOS XBRL, Oct 27, 2025).

## PBPH over each window to Sep 11, 2026

| Window | Total return | S&P 500 | Gap to S&P 500 | Gap to Nasdaq-100 |
| --- | --- | --- | --- | --- |
| 3 months | +7.1% | +3.3% | +3.8 pts | +7.9 pts |
| 6 months | +9.2% | +16.0% | −6.9 pts | −11.5 pts |
| Since launch | +11.0% | +14.2% | −3.2 pts | −6.8 pts |

## Every published field

| Field | Value | Source |
| --- | --- | --- |
| Theme | Biotech and genomics | ETFIQ, editorial |
| Launched | Nov 25, 2025 | ETFIQ |
| Already in the S&P 500, by weight | 56.8% | ETFIQ |
| Active share vs the S&P 500 | 95.0% | ETFIQ |
| Already in the Nasdaq-100, by weight | 14.7% | ETFIQ |
| Active share vs the Nasdaq-100 | 97.4% | ETFIQ |
| Top ten holdings weight | 62.7% | ETFIQ |
| Holdings | 51 | ETFIQ |
| Holdings as of | Jan 31, 2026 | SEC N-PORT |
| Top holdings | ELI LILLY & CO 14.7%, JOHNSON & JOHNSON 9.1%, ABBVIE INC 6.5%, ROCHE HOLDING AG-GENUSSCHEIN 5.3%, NOVARTIS AG-REG 5.0%, MERCK & CO. INC. 4.7%, ASTRAZENECA PLC 4.6%, NOVO NORDISK A/S-B 4.4%, AMGEN INC 4.3%, GILEAD SCIENCES INC 4.1% | ETFIQ |
| Net assets | $36m | SEC filing, whole fund, as filed for Jan 31, 2026 |
| Below its all-time high | −6.7% | ETFIQ |
| Expense ratio | 0.13% | 485BPOS XBRL, Oct 27, 2025 |
| Fee for the part that differs from the S&P 500, active expense ratio | 0.14% | ETFIQ |
| Closest funds by holdings overlap | GDOC 37%, THNR 34%, BMED 32%, AGNG 32%, CANC 31% | ETFIQ |

## Questions

### How much of PBPH is in S&P 500 companies?

By its holdings filed for Jan 31, 2026, 57% of PBPH by weight is stocks the S&P 500 already holds. Its active share against the index is 95%, so that share is the part doing something different.

### What does PBPH hold?

51 positions as filed for Jan 31, 2026, with the top ten at 63% of the fund. The largest are ELI LILLY & CO at 14.7%, JOHNSON & JOHNSON at 9.1%, ABBVIE INC at 6.5%.

### Has PBPH beaten the S&P 500?

Over the year to Sep 11, 2026 PBPH returned +11.0% with distributions reinvested, against +14.2% for the S&P 500, so it finished behind the index by 3.2 points.

### What does PBPH cost?

The prospectus expense ratio is 0.13% a year. Because 95% of the fund differs from the S&P 500, the fee on that differing part works out at 0.14%.


## Cite this page

ETFIQ, PBPH, data as of Sep 11, 2026. https://etfiq.com/funds/PBPH
Free to use with attribution; the underlying files are at https://etfiq.com/data/.

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