# IBBQ (Invesco Nasdaq Biotechnology ETF)

Invesco · Thematic ETFs · data as of Sep 11, 2026

IBBQ holds 249 stocks, and 62% of its weight is outside the S&P 500.

## Key facts

- IBBQ, already in the S&P 500: 38.1%, as of Sep 11, 2026.
- IBBQ, active share vs the S&P 500: 99.0%, as of Sep 11, 2026.
- IBBQ, top ten holdings: 44.4%, as of Sep 11, 2026.
- IBBQ, total return, 1 year: +43.5%, as of Sep 11, 2026.
- IBBQ, net assets: $67m (SEC filing, whole fund, as filed for May 31, 2026).
- IBBQ, expense ratio: 0.19% (485BPOS XBRL, Dec 18, 2025).

## IBBQ over each window to Sep 11, 2026

| Window | Total return | S&P 500 | Gap to S&P 500 | Gap to Nasdaq-100 |
| --- | --- | --- | --- | --- |
| 3 months | +16.7% | +3.3% | +13.4 pts | +17.5 pts |
| 6 months | +21.4% | +16.0% | +5.4 pts | +0.7 pts |
| 1 year | +43.5% | +17.5% | +26.0 pts | +20.5 pts |
| 3 years | +72.6% | +77.9% | −5.3 pts | −22.5 pts |
| Since launch | +41.1% | +93.4% | −52.3 pts | −75.0 pts |

## Every published field

| Field | Value | Source |
| --- | --- | --- |
| Theme | Biotech and genomics | ETFIQ, editorial |
| Launched | Jun 11, 2021 | ETFIQ |
| Already in the S&P 500, by weight | 38.1% | ETFIQ |
| Active share vs the S&P 500 | 99.0% | ETFIQ |
| Already in the Nasdaq-100, by weight | 33.5% | ETFIQ |
| Active share vs the Nasdaq-100 | 97.4% | ETFIQ |
| Top ten holdings weight | 44.4% | ETFIQ |
| Holdings | 249 | ETFIQ |
| Holdings as of | Sep 10, 2026 | the issuer’s daily file |
| Top holdings | Vertex Pharmaceuticals Inc 8.1%, Amgen Inc 8.1%, Gilead Sciences Inc 7.6%, Regeneron Pharmaceuticals Inc 5.5%, Moderna Inc 3.7%, Revolution Medicines Inc 2.9%, Alnylam Pharmaceuticals Inc 2.2%, Biogen Inc 2.1%, Illumina Inc 2.1%, Roivant Sciences Ltd 2.0% | ETFIQ |
| Net assets | $67m | SEC filing, whole fund, as filed for May 31, 2026 |
| Below its all-time high | −6.4% | ETFIQ |
| Expense ratio | 0.19% | 485BPOS XBRL, Dec 18, 2025 |
| Fee for the part that differs from the S&P 500, active expense ratio | 0.19% | ETFIQ |
| Closest funds by holdings overlap | BBH 53%, PBE 38%, BBP 35%, BMED 34%, FBT 33% | ETFIQ |

## Questions

### How much of IBBQ is in S&P 500 companies?

By its holdings published by its issuer for Sep 10, 2026, 38% of IBBQ by weight is stocks the S&P 500 already holds. Its active share against the index is 99%, so that share is the part doing something different.

### What does IBBQ hold?

249 positions as published by its issuer for Sep 10, 2026, with the top ten at 44% of the fund. The largest are Vertex Pharmaceuticals Inc at 8.1%, Amgen Inc at 8.1%, Gilead Sciences Inc at 7.6%.

### Has IBBQ beaten the S&P 500?

Over the year to Sep 11, 2026 IBBQ returned +43.5% with distributions reinvested, against +17.5% for the S&P 500, so it finished ahead of the index by 26.0 points.

### What does IBBQ cost?

The prospectus expense ratio is 0.19% a year. Because 99% of the fund differs from the S&P 500, the fee on that differing part works out at 0.19%.


## Cite this page

ETFIQ, IBBQ, data as of Sep 11, 2026. https://etfiq.com/funds/IBBQ
Free to use with attribution; the underlying files are at https://etfiq.com/data/.

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