{"url":"https://etfiq.com/compare/themes/idna-vs-xbi","section":"compare","title":"IDNA vs XBI: which is really different? | ETFIQ","description":"IDNA and XBI hold 20% of their weight in the same names, and IDNA returned +73.5% over the year. Returns and overlap to Oct 9, 2026.","as_of":"Oct 9, 2026","structured_data":[{"@type":"FAQPage","mainEntity":[{"@type":"Question","name":"Do IDNA and XBI hold the same stocks?","acceptedAnswer":{"@type":"Answer","text":"By their latest filings, 20% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share."}},{"@type":"Question","name":"Which is more different from the S&P 500, IDNA or XBI?","acceptedAnswer":{"@type":"Answer","text":"IDNA has 25% of its weight in S&P 500 names and XBI has 13%, so IDNA differs more from the index."}},{"@type":"Question","name":"Which is cheaper, IDNA or XBI?","acceptedAnswer":{"@type":"Answer","text":"IDNA charges 0.47% a year and XBI charges 0.35%, so XBI is cheaper. Fees come from each fund's prospectus."}}]},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"ETFIQ","item":"https://etfiq.com/"},{"@type":"ListItem","position":2,"name":"Thematic ETFs","item":"https://etfiq.com/themes/"},{"@type":"ListItem","position":3,"name":"IDNA vs XBI","item":"https://etfiq.com/compare/themes/idna-vs-xbi"}]},{"@type":"WebPage","name":"IDNA vs XBI: which is really different?","description":"IDNA and XBI hold 20% of their weight in the same names, and IDNA returned +73.5% over the year. Returns and overlap to Oct 9, 2026.","url":"https://etfiq.com/compare/themes/idna-vs-xbi","dateModified":"2026-10-10","abstract":"IDNA and XBI hold 20% of their weight in the same names, and IDNA returned +73.5% over the year.","publisher":{"@id":"https://etfiq.com/#org"},"isPartOf":{"@id":"https://etfiq.com/#website"},"speakable":{"@type":"SpeakableSpecification","cssSelector":[".verdict",".faq"]}},{"@type":"Dataset","name":"ETFIQ comparison of IDNA and XBI","description":"IDNA and XBI hold 20% of their weight in the same names, and IDNA returned +73.5% over the year. Returns and overlap to Oct 9, 2026.","dateModified":"2026-10-10","creator":{"@id":"https://etfiq.com/#org"},"isAccessibleForFree":true,"url":"https://etfiq.com/compare/themes/idna-vs-xbi","license":"https://etfiq.com/license/","publisher":{"@id":"https://etfiq.com/#org"},"inLanguage":"en","creativeWorkStatus":"Published","distribution":[{"@type":"DataDownload","encodingFormat":"application/json","contentUrl":"https://etfiq.com/data/thematic.json"}],"variableMeasured":["Weight overlap with the S&P 500","Active share","Holdings","Top ten share of the fund","Total return","Fee for the differing part","Expense ratio"],"keywords":["exchange-traded funds","ETF","Thematic ETFs","fund data","SEC filings"]}],"characters":7670,"truncated":true,"content":"ETFIQ / Thematic ETFs / Head to head / IDNA vs XBI \n ETFIQ etfiq.com \u00b7 independent ETF data \n\n Data as of Oct 9, 2026 .\n\n IDNA vs XBI: which is really different?\n\n IDNA and XBI hold 20% of their weight in the same names, and IDNA returned +73.5% over the year.\n Copy this for sharing \n \n XBI costs 0.12 points a year less; their one-year returns differ by 28.5 points; XBI is far larger, $9.9bn against $320m.\n IDNA and XBI at a glance. As of Oct 9, 2026. Source: ETFIQ. IDNA XBI \n Expense ratio 0.47% 0.35% \n Net assets, IDNA as of Oct 9, 2026 and XBI as of Oct 8, 2026 $320m $9.9bn \n Total return, ","source":"ETFIQ, independent ETF data. Recomputed nightly from public filings and prices.","publisher":{"@id":"https://etfiq.com/#org","name":"ETFIQ","url":"https://etfiq.com"},"license":"https://etfiq.com/license/","license_text":"Figures ETFIQ computes are free to use with attribution: ETFIQ (etfiq.com). Issuer data stays under its owner's terms.","citation":"ETFIQ, IDNA against XBI, data as of Oct 9, 2026. https://etfiq.com/compare/themes/idna-vs-xbi","a":{"ticker":"IDNA","name":"iShares Genomics Immunology and Healthcare ETF","issuer":"iShares","desk":"themes","as_of":"2026-10-09","verdict":"IDNA holds 52 stocks, and 75% of its weight is outside the S&P 500.","url":"https://etfiq.com/funds/idna","key_facts":[{"label":"Already in the S&P 500","value":"25.4%","as_of":"2026-10-09","source":null},{"label":"Active share vs the S&P 500","value":"99.1%","as_of":"2026-10-09","source":null},{"label":"Top ten holdings","value":"48.1%","as_of":"2026-10-09","source":null},{"label":"Total return, 1 year","value":"+73.5%","as_of":"2026-10-09","source":null},{"label":"Net assets","value":"$320m","as_of":"2026-10-09","source":"the issuer\u2019s own daily fund list, as of Oct 9, 2026"},{"label":"Expense ratio","value":"0.47%","as_of":"2026-10-09","source":"485BPOS XBRL, Nov 21, 2025"}]},"b":{"ticker":"XBI","name":"State Street(R) SPDR(R) S&P(R) Biotech ETF","issuer":"State Street","desk":"themes","as_of":"2026-10-09","verdict":"XBI holds 165 stocks, and 87% of its weight is outside the S&P 500.","url":"https://etfiq.com/funds/xbi","key_facts":[{"label":"Already in the S&P 500","value":"12.7%","as_of":"2026-10-09","source":null},{"label":"Active share vs the S&P 500","value":"98.4%","as_of":"2026-10-09","source":null},{"label":"Top ten holdings","value":"16.9%","as_of":"2026-10-09","source":null},{"label":"Total return, 1 year","value":"+45.0%","as_of":"2026-10-09","source":null},{"label":"Net assets","value":"$9.9bn","as_of":"2026-10-09","source":"the issuer\u2019s own daily fund list, as of Oct 8, 2026"},{"label":"Expense ratio","value":"0.35%","as_of":"2026-10-09","source":"485BPOS XBRL, Oct 24, 2025"}]},"overlap_pct":20,"full_text_at":"https://etfiq.com/compare/themes/idna-vs-xbi"}